CENTOGENE Reports Second Quarter and First Half 2022 Financial Results
Centogene N.V. (Nasdaq: CNTG) reported unaudited financial results for Q2 and H1 2022, showing a 21.6% increase in revenues to €11.2 million. The Diagnostics segment saw an 18.3% rise to €7.5 million, while the Pharma segment increased 29% to €3.7 million. Despite a net loss of €11.9 million in Q2, the loss improved by 11.9% YoY. Total revenues for H1 were €21.4 million, up 12.6%. The company anticipates 2022 revenue growth between 9% to 13%, reaching €46.5 to €48.2 million.
- Second quarter revenues up 21.6% to €11.2 million.
- Diagnostics segment revenue increased by 18.3% to €7.5 million.
- Pharma segment revenue grew by 29% to €3.7 million.
- Adjusted EBITDA increased 289% in Q2 to €3.5 million.
- Cash and cash equivalents up to €33.5 million from €17.8 million.
- Net loss from continuing operations of €11.9 million in Q2.
- H1 net loss of €23.1 million, despite YoY improvement.
CAMBRIDGE, Mass. and ROSTOCK, Germany and BERLIN, Dec. 22, 2022 (GLOBE NEWSWIRE) -- Centogene N.V. (Nasdaq: CNTG), the essential life science partner for data-driven answers in rare and neurodegenerative diseases, today announced unaudited financial results for the second quarter and first half ended June 30, 2022 and updated its fiscal year 2022 financial outlook. The quarterly and half year results are compared to the same periods in the prior year, unless otherwise specified, and reflect revisions as described below.
Second Quarter 2022 - Financial Highlights
- Overall revenues increased by
21.6% year-over-year to€11.2 million - Diagnostics segment revenues increased by
18.3% year-over-year to€7.5 million - Pharmaceutical segment (“Pharma”) revenues increased by
29% year-over-year to€3.7 million - Net loss from continuing operations of
€11.9 million in the second quarter of 2022, an improvement of11.9% compared to net loss from continuing operations of€13.5 million in the second quarter of 2021. (Excludes discontinued operations reflecting the Covid-19 testing business exited first quarter of 2022.) - Total segment adjusted EBITDA (reflecting the Diagnostics and Pharma segment) of
€3.5 million was recorded in the second quarter of 2022, an improvement of289% compared to€0.9 million in the second quarter of 2021.
First Half 2022 - Financial Highlights
- Overall revenues increased by
12.6% year-over-year to€21.4 million - Diagnostics segment revenues increased by
15.3% year-over-year to€14.5 million , mainly driven by34.7% growth in test requests received for higher value Whole Exome Sequencing (WES) and Whole Genome Sequencing (WGS). - Pharma revenues increased by
7.1% year-over-year to€6.9 million , mainly driven by increased activity in the clinical studies of our pharmaceutical partners. - Net loss from continuing operations of
€23.1 million in the first half of 2022, an improvement of16.9% compared to net loss from continuing operations of€27.8 million in the first half of 2021. - Total segment adjusted EBITDA (reflecting the Diagnostics and Pharma segment) of
€5.3 million in the first half of 2022, an improvement of60.6% compared to€3.3 million in the first half of 2021, mainly reflecting gross margin improvements in both segments. - Cash and cash equivalents were
€33.5 million as of June 30, 2022, compared to€17.8 million as of December 31, 2021.
Kim Stratton, Chief Executive Officer at CENTOGENE stated, “The current year is part of a transition at CENTOGENE, with renewed focus on the Core Business and exit of the COVID business. We are delivering on our goals in the Diagnostics segment, continuing to show double digit growth (+
Commenting on the financial performance, Miguel Coego, Chief Financial Officer of CENTOGENE noted, “The second quarter has been another period of improvements in efficiencies and business operations, including managing margins and corporate expenses. The reporting of our results was delayed due to a lengthier than anticipated review of reimbursements in the U.S. for diagnostic tests done by a third party service provider. The overall revenue impact were revisions of approximately
Recent Business Highlights
Corporate
- Added ~24,000 individuals to the CENTOGENE Biodatabank in the second quarter of 2022; with nearly 700,000 patients total represented from over 120 highly diverse countries, estimated over
70% of whom are of non-European descent. - Authored 38 peer-reviewed scientific publications in the first half of 2022, focusing on advanced multiomic diagnostics and generating critical insights into an array of diseases, including rare genetic and neurological diseases, such as Parkinson’s disease, Gaucher disease, and Niemann-Pick disease.
- Announced the appointment of Mary Sheahan as a member ad interim of the Supervisory Board, to be confirmed at the Company’s next General Meeting of Shareholders; it is planned that Ms. Sheahan will assume the role of Chair of the Audit Committee.
- Strengthened our Core Business focus with key additions to the team including appointment of CFO and expansion of Pharma leadership team bringing significant sector and commercial expertise.
- Closed the
$20 million second tranche of secured loan from Oxford Finance, with funding expected before the end of the year.
Pharma
- 45 active collaborations as of June 30, 2022; 12 contracts were signed in the first half of 2022; 10 of which with existing customers.
- Launched the Biodata Network, a portfolio of data-driven partnering solutions for biopharma and research institutions; collaborating with BC Platforms to increase access to tranche of 80,000 genetic sequences via Global Data Partner Network, BCRQUEST.com.
- Expanded partnership with Agios Pharmaceuticals for clinical development of PYRUKYND® (mitapivat) to treat children with rare blood disease.
- Leading three observational studies for patient finding and market access in collaboration with our pharma partners in rare and neurodegenerative disorders.
Diagnostics
- Reported order intake of approximately 16,300 test requests in our diagnostics segment in the second quarter of 2022, representing an increase of approximately
17% as compared to 13,900 test requests in the second quarter of 2021. - Published study in the European Journal of Human Genetics revealing the power of multiomic testing in diagnosing and accelerating treatments for patients with Inherited Metabolic Disorders (IMDs).
- Awarded a three-year tender for genetic testing in Malta by the Ministry for Health.
- Launched the latest version of CentoArray, a genome-wide analysis optimized for best cytogenetic disease coverage and designed to represent the latest clinical and genetic insights; cytogenic variations known to cause a broad range of developmental disorders, primarily neurodevelopmental and congenital anomalies.
- Received CE-mark for CentoCloud, making it one of the only decentralized SaaS and clinical decision support platforms compliant with European IVD regulatory framework.
- Contributed to Europe-wide efforts to update guidelines for WGS in rare disease diagnostics.
Second Quarter and First Half 2022 Financial Summary
Our total revenues for the second quarter and first half of 2022 were
Revenues from our pharmaceutical segment were
Revenues from our pharmaceutical segment were
During the first half of 2022, we entered into twelve new collaborations and successfully completed twelve collaborations resulting in a total of 45 active collaborations at June 30, 2022, compared to 45 active collaborations at December 31, 2021 and 53 active collaborations as of June 30, 2021. Revenues from our new collaborations totalled
Revenues from our diagnostics segment were
The increase in revenues was primarily related to an increase in test requests for WES and WGS during the second quarter of 2022. Total revenues from WES and WGS for the second quarter of 2022 amounted to
Total revenues from WES and WGS for the first half of 2022 amounted to
Cost of sales decreased by
As a result of the above factors, our gross profit increased by
Research and development expenses increased by
General administrative expenses decreased by
Selling expenses for the second quarter and first half of 2022 were
There were no impairment expenses for financial assets incurred for the second quarter and first half of 2022 as compared to
Other operating income decreased by
Other operating expenses which relate to currency losses increased by
The increase in currency losses in the second quarter and first half of 2022 mainly relates to transactions denominated in USD that have been impacted by the devaluation of the EUR against the USD in the three and six months period.
The change in net financial costs by
As a result of the factors described above, our loss before taxes from continuing operations for the second quarter and first half of 2022 was
Adjusted EBITDA from our pharmaceutical segment for the second quarter and first half of 2022 was
Adjusted EBITDA from our diagnostics segment for the second quarter and first half of 2022, was
Revision of previously issued financial statements
During the preparation of unaudited condensed consolidated financial statements as of and for the three months ended March 31, 2022, the Group identified unadjusted differences related to certain property, plant and equipment and lease liabilities balances on the consolidated statement of financial position and cost of sales and other operating income amounts in the statements of comprehensive loss as of and for the year ended December 31, 2021. The unadjusted differences were related to COVID segment which was discontinued as of March 31, 2022.
During the preparation of the unaudited financial results for the second quarter ended June 30, 2022, the Group identified unadjusted differences related to revenue recognized and impairment losses for the years ended December 31, 2021, December 31, 2020 and December 31, 2019 and trade receivables outstanding as of December 31, 2021, 2020 and 2019 for the Diagnostics segment.
Management assessed the materiality of these unadjusted differences on the previously issued consolidated financial statements and concluded that the errors were not material to any period presented. The Group revised the relevant amounts for the previously issued financial statements. Refer to “Note 2 - Revision of previously issued financial statements” to our unaudited interim condensed consolidated financial statements for the three and six months ended June 30, 2022 and 2021 for further details.
2022 Financial Guidance
The Company expects to report 2022 annual revenue growth between
Earnings Cadence
The Company’s next financial report will be the FY 2022 results. Going forward, the Company plans to follow a semi-annual reporting cadence.
About CENTOGENE
CENTOGENE’s mission is to provide data-driven, life-changing answers to patients, physicians, and pharma companies for rare and neurodegenerative diseases. We integrate multiomic technologies with the CENTOGENE Biodatabank – providing dimensional analysis to guide the next generation of precision medicine. Our unique approach enables rapid and reliable diagnosis for patients, supports a more precise physician understanding of disease states, and accelerates and de-risks targeted pharma drug discovery, development, and commercialization.
Since our founding in 2006, CENTOGENE has been offering rapid and reliable diagnosis – building a network of approximately 30,000 active physicians. Our ISO, CAP, and CLIA certified multiomic reference laboratories in Germany utilize Phenomic, Genomic, Transcriptomic, Epigenomic, Proteomic, and Metabolomic datasets. This data is captured in our CENTOGENE Biodatabank, with nearly 700,000 patients represented from over 120 highly diverse countries, over
By translating our data and expertise into tangible insights, we have supported over 50 collaborations with pharma partners. Together, we accelerate and de-risk drug discovery, development, and commercialization in target & drug screening, clinical development, market access and expansion, as well as offering CENTOGENE Biodatabank Licenses and Insight Reports to enable a world healed of all rare and neurodegenerative diseases.
To discover more about our products, pipeline, and patient-driven purpose, visit www.centogene.com and follow us on LinkedIn.
Forward-Looking Statements
This press release contains “forward-looking statements” within the meaning of the U.S. federal securities laws. Statements contained herein that are not clearly historical in nature are forward-looking, and the words “anticipate,” “believe,” “continues,” “expect,” “estimate,” “intend,” “project,” and similar expressions and future or conditional verbs such as “will,” “would,” “should,” “could,” “might,” “can,” and “may,” are generally intended to identify forward-looking statements. Such forward-looking statements involve known and unknown risks, uncertainties, and other important factors that may cause CENTOGENE’s actual results, performance, or achievements to be materially different from any future results, performance, or achievements expressed or implied by the forward- looking statements. Such risks and uncertainties include, among others, negative economic and geopolitical conditions and instability and volatility in the worldwide financial markets, possible changes in current and proposed legislation, regulations and governmental policies, pressures from increasing competition and consolidation in our industry, the expense and uncertainty of regulatory approval, including from the U.S. Food and Drug Administration, our reliance on third parties and collaboration partners, including our ability to manage growth, execute our business strategy and enter into new client relationships, our dependency on the rare disease industry, our ability to manage international expansion, our reliance on key personnel, our reliance on intellectual property protection, fluctuations of our operating results due to the effect of exchange rates, our ability to streamline cash usage, our continued ongoing compliance with covenants linked to financial instruments, our requirement for additional financing, or other factors. For further information on the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to CENTOGENE’s business in general, see CENTOGENE’s risk factors set forth in CENTOGENE’s Form 20-F filed on March 31, 2022, with the Securities and Exchange Commission (the “SEC”) and subsequent filings with the SEC. Any forward-looking statements contained in this press release speak only as of the date hereof, and CENTOGENE’s specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events, or otherwise.
Media Contact:
Ben Legg
Corporate Communications
press@centogene.com
Lennart Streibel
Investor Relations
investor.relations@centogene.com
Centogene N.V.
Unaudited consolidated statements of comprehensive loss
(in EUR k)
| For the three months ended June 30 | For the six months ended June 30 | |||||||||||
| 2022 | 2021* (Revised) | 2022 | 2021* (Revised) | |||||||||
| Revenue | 11,198 | 9,209 | 21,389 | 19,002 | ||||||||
| Cost of sales | 6,586 | 6,617 | 13,036 | 12,825 | ||||||||
| Gross profit | 4,612 | 2,592 | 8,353 | 6,177 | ||||||||
| Research and development expenses | 4,457 | 4,053 | 9,071 | 8,388 | ||||||||
| General administrative expenses | 9,378 | 10,494 | 17,284 | 22,090 | ||||||||
| Selling expenses | 2,798 | 1,942 | 5,192 | 3,891 | ||||||||
| Impairment of financial assets | — | 544 | — | 615 | ||||||||
| Gain on reversal of financial asset impairment | 1,035 | — | 919 | — | ||||||||
| Other operating income | 657 | 1,276 | 1,390 | 1,642 | ||||||||
| Other operating expenses | 506 | 2 | 507 | 36 | ||||||||
| Operating loss | (10,835 | ) | (13,167 | ) | (21,392 | ) | (27,201 | ) | ||||
| Changes in fair value of warrants | 1,401 | — | 1,639 | — | ||||||||
| Interest and similar income | — | — | 1 | — | ||||||||
| Interest and similar expense | 2,278 | 175 | 3,137 | 434 | ||||||||
| Financial costs, net | (877 | ) | (175 | ) | (1,497 | ) | (434 | ) | ||||
| Loss before taxes from continuing operations | (11,712 | ) | (13,342 | ) | (22,889 | ) | (27,635 | ) | ||||
| Income tax expenses | 175 | 124 | 179 | 124 | ||||||||
| Loss for the period from continuing operations | (11,887 | ) | (13,466 | ) | (23,068 | ) | (27,759 | ) | ||||
| Net income from discontinued operations, net of tax | 1,539 | 5,110 | 6,140 | 14,338 | ||||||||
| Loss for the period | (10,348 | ) | (8,356 | ) | (16,928 | ) | (13,421 | ) | ||||
| Other comprehensive income/(loss), all attributable to equity holders of the parent | (71 | ) | (191 | ) | 23 | (70 | ) | |||||
| Total comprehensive loss | (10,419 | ) | (8,547 | ) | (16,905 | ) | (13,491 | ) | ||||
| Attributable to: | ||||||||||||
| Equity holders of the parent | (10,145 | ) | (8,559 | ) | — | (13,537 | ) | |||||
| Non‑controlling interests from continuing operations | — | — | (16,658 | ) | — | |||||||
| Non‑controlling interests from discontinued operations | (274 | ) | 12 | (247 | ) | 46 | ||||||
| (10,419 | ) | (8,547 | ) | (16,905 | ) | (13,491 | ) | |||||
| Net loss per share - Basic and diluted from (in EUR) | ||||||||||||
| Continuing operations | (0.44 | ) | (0.61 | ) | (0.88 | ) | (1.24 | ) | ||||
| Loss attributable to parent | (0.38 | ) | (0.38 | ) | (0.64 | ) | (0.60 | ) | ||||
*The comparative numbers have been re-presented as a result of the discontinued operations.
Centogene N.V.
Unaudited consolidated statements of financial position
(in EUR k)
| Assets | June 30, 2022 | Dec 31, 2021 | Jan 1 2021 | |||
| Revised | Revised | |||||
| Non‑current assets | ||||||
| Intangible assets | 7,576 | 9,194 | 12,407 | |||
| Property, plant and equipment* | 7,217 | 9,464 | 16,590 | |||
| Right-of-use assets | 17,059 | 18,904 | 22,120 | |||
| Other assets | 2,972 | 2,972 | 1,967 | |||
| 34,824 | 40,534 | 53,084 | ||||
| Current assets | ||||||
| Inventories | 2,154 | 3,869 | 11,405 | |||
| Trade receivables and contract assets* | 15,716 | 23,646 | 29,250 | |||
| Other assets | 3,954 | 5,453 | 8,286 | |||
| Cash and cash equivalents | 33,515 | 17,818 | 48,156 | |||
| 55,339 | 50,786 | 97,097 | ||||
| 90,163 | 91,320 | 150,181 |
| Equity and liabilities | June 30, 2022 | Dec 31, 2021 | Jan 1 2021 | ||||||
| Revised | Revised | ||||||||
| Equity | |||||||||
| Issued capital | 3,250 | 2,708 | 2,654 | ||||||
| Capital reserve | 144,027 | 133,897 | 125,916 | ||||||
| Accumulated deficit and other reserves* | (126,171 | ) | (109,414 | ) | (63,477 | ) | |||
| Non‑controlling interests | (54 | ) | 193 | 95 | |||||
| 21,052 | 27,384 | 65,188 | |||||||
| Non‑current liabilities | |||||||||
| Non‑current loans | 23,632 | — | 401 | ||||||
| Lease liabilities* | 13,770 | 15,394 | 17,677 | ||||||
| Deferred tax liabilities | 49 | 79 | 207 | ||||||
| Government grants | 7,305 | 8,028 | 8,950 | ||||||
| Other liabilities* | — | 1,018 | 640 | ||||||
| Warrants liability | 1,194 | — | — | ||||||
| 45,950 | 24,519 | 27,875 | |||||||
| Current liabilities | |||||||||
| Government grants | 1,351 | 1,368 | 1,342 | ||||||
| Current loans | 1,730 | 3,815 | 2,492 | ||||||
| Lease liabilities* | 2,713 | 3,330 | 3,528 | ||||||
| Trade payables | 4,757 | 11,252 | 31,736 | ||||||
| Liabilities from income taxes | 124 | 178 | 58 | ||||||
| Other liabilities* | 12,486 | 19,474 | 17,962 | ||||||
| 23,161 | 39,417 | 57,118 | |||||||
| 90,163 | 91,320 | 150,181 | |||||||
* Property, plant and equipment and lease liabilities as of December 31, 2021 and Trade receivables and contract assets and other liabilities as of December 31, 2021 and January 1, 2021 have been revised. Refer to Note 2 – Revision of previously issued financial statements.
Centogene N.V.
Unaudited interim condensed consolidated statements of cash flows
for the six months ended June 30, 2022 and 2021
(in EUR k)
| For the six months ended June 30 | ||||||
| 2022 | 2021 (Revised) | |||||
| Operating activities | ||||||
| Loss before taxes from continuing operations | (22,889 | ) | (27,635 | ) | ||
| Income before taxes from discontinued operations | 6,153 | 14,338 | ||||
| Loss before taxes | (16,736 | ) | (13,297 | ) | ||
| Adjustments to reconcile loss to cash flow from operating activities | ||||||
| Amortization and depreciation | 5,958 | 6,670 | ||||
| Interest income | (1 | ) | ||||
| Interest expense | 3,137 | 471 | ||||
| Expected credit loss allowances on trade receivables and contract assets | — | 675 | ||||
| Gain on revaluation of credit loss allowance on trade receivables and contract assets | (919 | ) | — | |||
| Gain on disposal of property, plant and equipment | (683 | ) | — | |||
| Share‑based payment (true up)/ expenses | (1,386 | ) | 4,276 | |||
| Fair value adjustments of warrants | (1,639 | ) | — | |||
| Tax expense | 192 | 124 | ||||
| Other non‑cash items | (580 | ) | 126 | |||
| Changes in operating assets and liabilities | ||||||
| Inventories | 1,715 | 2,124 | ||||
| Trade receivables and contract assets | 8,849 | 10,371 | ||||
| Other assets | 1,499 | 328 | ||||
| Trade payables | (6,495 | ) | (17,722 | ) | ||
| Other liabilities | (8,060 | ) | (1,975 | ) | ||
| Thereof cash flow (used in) continuing operating activities | (22,504 | ) | (16,603 | ) | ||
| Thereof cash flow from discontinued operating activities | 7,355 | 8,773 | ||||
| Net cash flow (used in) operating activities | (15,149 | ) | (7,830 | ) | ||
| Investing activities | ||||||
| Cash paid for investments in intangible assets | (151 | ) | (2,089 | ) | ||
| Cash paid for investments in property, plant and equipment | (843 | ) | (2,696 | ) | ||
| Cash received for disposal of property, plant and equipment | 779 | — | ||||
| Thereof cash flow (used in) continuing investing activities | (994 | ) | (2,397 | ) | ||
| Thereof cash flow from/(used in) discontinued investing activities | 779 | (2,388 | ) | |||
| Cash flow received/ (used in) investing activities | (215 | ) | (4,785 | ) | ||
| Financing activities | ||||||
| Cash received from issuance of shares | 12,058 | — | ||||
| Cash received from issuance of warrants | 2,833 | — | ||||
| Cash received from loans | 21,695 | 1,769 | ||||
| Cash repayments of loans | (148 | ) | (185 | ) | ||
| Cash repayments of lease liabilities | (2,241 | ) | (2,263 | ) | ||
| Interest received | 1 | |||||
| Interest paid | (3,137 | ) | (82 | ) | ||
| Thereof net cash flow from/(used in) continuing financing activities | 31,541 | (404 | ) | |||
| Thereof net cash flow (used in) discontinued financing activities | (481 | ) | (357 | ) | ||
| Net cash flow from/ (used in) financing activities | 31,061 | (761 | ) | |||
| Changes in cash and cash equivalents | 15,697 | (13,376 | ) | |||
| Cash and cash equivalents at the beginning of the period | 17,818 | 48,156 | ||||
| Cash and cash equivalents at the end of the period | 33,515 | 34,780 | ||||
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