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Compass Pathways Plc - CMPS STOCK NEWS

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Overview of Compass Pathways Plc

Compass Pathways Plc (Nasdaq: CMPS) is a biotechnology company dedicated to transforming mental health care through evidence-based innovation. Headquartered in London, UK, with additional offices in New York and San Francisco, Compass is pioneering the development of psilocybin-based therapies for patients suffering from treatment-resistant depression (TRD) and other severe mental health conditions. The company's mission is to accelerate patient access to groundbreaking treatments by integrating advances in neuroscience, psychopharmacology, psychotherapy, and digital health platforms.

Core Business and Innovation

At the heart of Compass Pathways' business model is COMP360, a proprietary, high-purity crystalline formulation of synthetic psilocybin. This investigational therapy is designed to be administered in conjunction with psychological support, creating a holistic treatment model for mental health conditions that do not respond to conventional therapies. COMP360 has received Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA) and Innovative Licensing and Access Pathway (ILAP) designation in the UK, underscoring its potential to address significant unmet needs in mental health care.

The company is advancing COMP360 through rigorous clinical trials, including the largest randomized, controlled, double-blind psilocybin treatment program ever conducted. Phase 2 studies have demonstrated promising results, with significant improvements in depressive symptoms for TRD patients. In addition to TRD, Compass is exploring the efficacy of COMP360 for other conditions such as post-traumatic stress disorder (PTSD) and anorexia nervosa, further broadening its therapeutic potential.

Industry Context and Market Position

Compass Pathways operates within the rapidly evolving field of psychedelic-assisted therapies, a niche segment of the broader mental health care and biotechnology industries. This sector is gaining traction as traditional treatments often fail to address the complex needs of patients with severe mental health conditions. The company's focus on TRD positions it within a high-demand market segment where millions of patients lack effective treatment options.

Unlike competitors who may focus solely on drug development, Compass is building a comprehensive ecosystem to support the delivery of psychedelic therapies. This includes developing scalable care pathways, training healthcare providers, and collaborating with leading mental health organizations to ensure responsible and effective treatment deployment. These efforts differentiate Compass as a holistic innovator in the mental health space.

Strategic Partnerships and Collaborations

Compass Pathways has established a robust network of research collaborations to refine and scale its treatment models. Recent partnerships include agreements with organizations like Journey Clinical, Mindful Health Solutions, and Greenbrook TMS. These collaborations focus on areas such as therapist training, patient care pathways, and healthcare reimbursement processes, ensuring that COMP360 can be integrated seamlessly into existing healthcare systems if approved.

For example, Compass is working with Journey Clinical to explore innovative care pathways for TRD patients, leveraging Journey's extensive network of licensed therapists and expertise in psychedelic-assisted psychotherapy. Similarly, its collaboration with Mindful Health Solutions aims to address challenges in patient care delivery and therapist training, further solidifying Compass's position as a leader in the field.

Commitment to Evidence-Based Mental Health Innovation

Compass Pathways is deeply committed to advancing the scientific understanding of psychedelic therapies. Its clinical programs are designed to meet the highest standards of rigor and transparency, ensuring that the safety and efficacy of COMP360 are thoroughly evaluated. By combining cutting-edge research with a patient-centric approach, Compass is setting a new standard for mental health care innovation.

The company's vision extends beyond individual treatments to encompass a broader transformation of the mental health care landscape. By addressing both the therapeutic and systemic challenges of mental health care, Compass aims to create a world where mental well-being is accessible to all.

Conclusion

Compass Pathways Plc represents a pioneering force in the mental health care industry, blending scientific innovation with a holistic approach to patient care. Through its development of COMP360 and its strategic focus on scalability and collaboration, the company is poised to redefine the treatment paradigm for severe mental health conditions. As the demand for effective mental health solutions continues to grow, Compass Pathways stands at the forefront of this transformative field, offering hope to millions of patients worldwide.

Rhea-AI Summary
Compass Pathways plc (Nasdaq: CMPS) and Hackensack Meridian Health have announced a research collaboration agreement to inform the delivery model design of investigational COMP360 psilocybin treatment for treatment-resistant depression. The collaboration aims to improve health outcomes and patient experiences. COMP360 is Compass's proprietary formulation of synthetic psilocybin, administered with psychological support. Hackensack Meridian Health, a leading not-for-profit healthcare organization, will leverage its extensive experience in treating depression to inform how new mental health treatments may be accessed by patients in the future.
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Compass Pathways plc (Nasdaq: CMPS) and Greenbrook TMS Inc. (NASDAQ: GBNH) have entered into a three-year research collaboration to explore scalable, commercial delivery models for COMP360 psilocybin treatment upon FDA approval. COMP360 has been designated a 'Breakthrough Therapy' by the FDA for treatment-resistant depression (TRD). The collaboration aims to improve patient care experience and therapist needs, as well as investigate the potential use of digital tools within Greenbrook TMS's care pathways.
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Compass Pathways plc (Nasdaq: CMPS) announced positive initial safety findings for investigational COMP360 psilocybin treatment in a phase 2 clinical trial for post-traumatic stress disorder (PTSD). The 24-hour data readout showed that COMP360 was well-tolerated with no serious adverse events. The study is being conducted in the UK and US, with safety and efficacy data expected to be announced in spring 2024.
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Compass Pathways plc (Nasdaq: CMPS) has appointed Teri Loxam as Chief Financial Officer (CFO), effective March 2024. Teri brings deep strategic experience from publicly traded companies in the pharmaceutical and biotechnology sectors. She will be based in the company’s New York City office.
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Compass Pathways plc (Nasdaq: CMPS) announced the publication of a paper in JAMA Psychiatry demonstrating the potential for investigational COMP360 psilocybin treatment in treatment-resistant bipolar type II disorder. The study conducted by Dr. Scott Aaronson at Sheppard Pratt, Baltimore, and funded by Compass, showed that all participants had lower MADRS scores with a mean change from baseline of -24.0 points at week 3, with 12 participants meeting the response criteria and 11 meeting the remission criteria. The study also reported no increase in the suicidality score, no manic symptoms, and no unexpected adverse events or difficulties with the dosing sessions reported throughout the study.
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Compass Pathways plc (Nasdaq: CMPS) announced the initiation of the UK component of its phase 3 program of investigational COMP360 psilocybin treatment in treatment-resistant depression (TRD). The research will take place in multiple sites in the UK, including at the Centre for Mental Health Research and Innovation in London, developed in partnership with South London and Maudsley NHS Foundation Trust and the Institute of Psychiatry, Psychology & Neuroscience at King’s College London. The phase 3 program is the largest randomized, controlled, double-blind psilocybin treatment clinical program ever conducted and follows promising results from Compass’s phase 2b study of COMP360 psilocybin treatment.
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COMPASS Pathways reports financial results for Q3 2023, with a cash position of $248.0 million as of September 30, 2023. The COMP360 phase 3 program is ongoing, and top-line data for COMP005 is expected in summer 2024. The company also expects top-line data for its phase 2 study in PTSD by the end of this year. COMPASS secured up to $285 million in private placement financing. The CEO expressed confidence in the clinical programs and pre-commercial work for a potential new drug application filing with the FDA.
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COMPASS Pathways announces CFO departure and appointment of interim CFO
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COMPASS Pathways appoints Daphne Karydas to its Board of Directors
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COMPASS Pathways announces results of AI study on psilocybin treatment in depression
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FAQ

What is the current stock price of Compass Pathways Plc (CMPS)?

The current stock price of Compass Pathways Plc (CMPS) is $3.54 as of March 10, 2025.

What is the market cap of Compass Pathways Plc (CMPS)?

The market cap of Compass Pathways Plc (CMPS) is approximately 334.1M.

What does Compass Pathways Plc do?

Compass Pathways develops psilocybin-based therapies, such as its proprietary COMP360, to treat treatment-resistant depression and other mental health conditions.

What is COMP360?

COMP360 is Compass Pathways' proprietary, high-purity crystalline formulation of synthetic psilocybin designed for use with psychological support in treating mental health conditions.

What makes Compass Pathways unique in the mental health industry?

Compass integrates psilocybin therapy with psychological support, develops scalable care models, and collaborates with mental health organizations to ensure effective and responsible treatment delivery.

What is treatment-resistant depression (TRD)?

TRD is a subset of major depressive disorder where patients do not respond adequately to existing treatment options, creating a significant need for innovative therapies like COMP360.

What regulatory designations has COMP360 received?

COMP360 has been designated a Breakthrough Therapy by the U.S. FDA and received Innovative Licensing and Access Pathway (ILAP) designation in the UK.

How does Compass Pathways collaborate with other organizations?

Compass partners with mental health organizations like Journey Clinical and Mindful Health Solutions to refine care pathways, train therapists, and explore scalable delivery models for COMP360.

What clinical trials is Compass Pathways conducting?

Compass is conducting phase 3 trials for COMP360 in treatment-resistant depression and phase 2 trials for conditions like PTSD and anorexia nervosa.

Where is Compass Pathways headquartered?

Compass Pathways is headquartered in London, UK, with offices in New York and San Francisco.

What challenges does Compass Pathways face?

Challenges include regulatory approval, public acceptance of psychedelic therapies, and scaling delivery models for widespread adoption.

What is Compass Pathways' long-term vision?

The company aims to transform mental health care by making evidence-based, innovative treatments like COMP360 widely accessible, fostering a world of mental well-being.
Compass Pathways Plc

Nasdaq:CMPS

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CMPS Stock Data

334.09M
79.62M
16.4%
45.16%
4.66%
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