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About Clearmind Medicine Inc. (CMND)
Clearmind Medicine Inc. (Nasdaq: CMND, FSE: CWY0) is a clinical-stage psychedelic pharmaceutical biotechnology company pioneering the development of novel psychedelic-derived therapeutics to address widespread and underserved health challenges. With a focus on non-hallucinogenic compounds, Clearmind aims to transform the treatment landscape for conditions such as alcohol use disorder (AUD), binge behavior, and other mental health disorders.
Innovative Therapeutic Solutions
The company’s flagship therapeutic, MEAI (5-methoxy-2-aminoindane), is a groundbreaking psychoactive molecule designed to regulate binge behaviors, including alcohol consumption, while providing a mild euphoric experience. MEAI-based treatments, such as CMND-100, are currently undergoing clinical trials to evaluate their safety, tolerability, and efficacy. Clearmind’s Phase I/IIa clinical trials, conducted in collaboration with leading institutions like Yale School of Medicine and Johns Hopkins University, underscore its commitment to rigorous scientific validation.
Expanding Intellectual Property Portfolio
Clearmind boasts an extensive and growing intellectual property (IP) portfolio, comprising 31 granted patents across 19 patent families, with protections secured in key jurisdictions such as the U.S., Europe, China, and India. This robust IP strategy covers innovative compounds, combination therapies, and delivery methods, ensuring the company’s competitive edge in the psychedelic pharmaceutical space. Recent patents include novel combinations of MEAI with N-Acylethanolamines and other compounds to enhance therapeutic efficacy and safety.
Collaborative Approach
Collaboration is central to Clearmind’s innovation strategy. The company partners with academic institutions like the Hebrew University of Jerusalem through Yissum Research Development Company and pharmaceutical firms such as SciSparc Ltd. These partnerships enable the development of next-generation psychedelic therapies targeting complex conditions like post-traumatic stress disorder (PTSD), opioid use disorder (OUD), and more.
Market Potential and Social Impact
Clearmind operates within the rapidly growing psychedelic therapeutics market, driven by increasing recognition of psychedelics’ potential in mental health treatment. The global market for AUD and PTSD treatments alone represents billions in unmet demand. Clearmind’s innovative solutions, such as its MEAI-based alcohol alternative developed in collaboration with Dr. Glitter Pty Ltd, aim to address these gaps by offering safer, non-addictive alternatives to traditional treatments.
Commitment to Safety and Accessibility
Clearmind’s therapeutic pipeline emphasizes safety and accessibility. By focusing on non-hallucinogenic psychedelic compounds, the company seeks to minimize risks while maximizing therapeutic benefits. This approach aligns with its mission to improve quality of life for patients worldwide, particularly those struggling with addiction and mental health disorders.
Future Outlook
As a pioneer in the psychedelic pharmaceutical industry, Clearmind Medicine Inc. is well-positioned to lead the next wave of innovation in mental health and addiction treatment. Its strategic focus on intellectual property, clinical validation, and collaborative partnerships underscores its potential to revolutionize the field and deliver transformative solutions to global healthcare challenges.
Clearmind Medicine Inc. (NASDAQ: CMND) has filed three provisional patent applications with the USPTO in collaboration with SciSparc Ltd. to develop innovative psychedelic-based treatments. The patents encompass combinations of LSD, psilocybin, DMT, and the active ingredient of CannAmide™, aimed at enhancing efficacy and safety for mental health therapies. Clearmind boasts 23 patents across seven families, positioning itself strongly in the psychedelic sector. The company's strategy focuses on providing safer, more effective treatments for mental health disorders and expanding their intellectual property portfolio.
Clearmind Medicine Inc. (NASDAQ: CMND) will attend the 2023 OurCrowd Global Investor Summit on February 15 in Jerusalem. CEO Dr. Adi Zuloff-Shani will discuss the company’s recent Nasdaq IPO with David Huberman from Greenberg Traurig. This session, titled “IPOs in a Down Market,” aims to provide insights into the IPO process and the challenges faced in the current economic climate. Clearmind focuses on developing psychedelic-derived therapeutics to address significant health issues, holding seven patent families, and aims to expand its intellectual property portfolio.
Clearmind Medicine Inc. (NASDAQ: CMND) will host a virtual investor conference titled “Psychedelics for Obesity” on February 28, 2023, at 8:30 AM EST. The event will highlight recent positive pre-clinical results for its drug candidate MEAI, aimed at treating obesity and metabolic syndrome. Professor Joseph Tam, leading the study from Hebrew University's Institute for Drug Research, will discuss these findings. CEO Dr. Adi Zuloff-Shani will outline the company's achievements and future goals. Clearmind focuses on developing psychedelic-derived therapeutics for significant health issues and is listed on NASDAQ under CMND.
Clearmind Medicine Inc. (NASDAQ: CMND) has announced promising results from a pre-clinical trial involving 2-Fluorodeschloroketamine (2-FDCK), an analogue of Ketamine, aimed at treating Major Depressive Disorder (MDD). Conducted in collaboration with Bar-Ilan University, the trial evaluated the effects of 2-FDCK on rodent models of depression. Results indicated superior efficacy of 2-FDCK over Ketamine, especially in chronic treatment settings. Clearmind's CEO highlighted the significance of these findings for patients with treatment-resistant depression, emphasizing the company's commitment to developing innovative psychedelic-derived therapeutics.
Clearmind Medicine (NASDAQ: CMND) announced its participation at Isranalytica 2023, a leading analytical chemistry conference. Professor Joseph Tam presented promising pre-clinical trial results for MEAI, its drug candidate aimed at treating obesity and metabolic syndrome. Tam's presentation titled "The Psychoactive Drug 5-Methoxy-2-aminoindane (MEAI) Ameliorates Obesity and its Metabolic Complications" showcased the drug's efficacy. CEO Dr. Adi Zuloff-Shani emphasized the importance of raising awareness within the scientific community to support future clinical programs. Clearmind focuses on developing psychedelic-derived therapeutics for untreated health issues.
Clearmind Medicine Inc. (Nasdaq, CSE: CMND) recently announced the successful completion of two innovative drug-discovery projects at the Hebrew University. These projects focus on developing novel psychedelic compounds aimed at enhancing therapeutic effects for under-treated health issues. Led by esteemed professors, the initiatives involved synthesizing synthetic molecules and evaluating psychedelic analogues for efficacy and safety. The promising results from these projects will allow Clearmind and Yissum to advance multiple new patent applications, expanding the company’s intellectual property portfolio. The firm remains committed to its mission of providing innovative solutions for mental health challenges.
Clearmind Medicine Inc. (CMND) announced promising pre-clinical results for its drug candidate MEAI, showing potential in treating substance addiction without affecting natural reward processes. Conducted at Bar Ilan University, the in-vivo studies revealed that MEAI, at a dose of 5mg/kg, significantly decreased cocaine craving, marking it as a potential first-of-its-kind treatment for cocaine addiction. The researchers confirmed that MEAI allows for the maintenance of natural rewards, distinguishing it from traditional addiction treatments. CEO Dr. Adi Zuloff-Shani emphasized the importance of these results in addressing cocaine addiction, which currently lacks dedicated therapies.
Clearmind Medicine Inc. (Nasdaq: CMND) has successfully manufactured batches of its MEAI-based molecule, CMND-100, for its first in-human clinical trial targeting Alcohol Use Disorder (AUD). This milestone indicates readiness to proceed with clinical testing. The drug was produced under Good Manufacturing Practices to meet FDA standards, aligning with the company's goal to develop psychedelic-derived therapeutics. Clearmind holds seven patent families and aims to expand its intellectual property portfolio as it advances its clinical program.
Clearmind Medicine Inc. (CMND) announced promising pre-clinical trial results for its drug candidate MEAI, aimed at treating obesity and metabolic syndrome. Conducted at the Hebrew University of Jerusalem, the trials demonstrated a 20% weight loss in rodents, improved insulin sensitivity, and reduced liver fat. MEAI treatment also decreased sucrose preference, indicating potential applications in addiction treatment. The global obesity drug market was valued at $1.9 billion in 2021, with further growth projected. Clearmind's progress underscores the drug's potential to address significant health issues.
Clearmind Medicine Inc. (NASDAQ:CMND) announces a new interview featuring CEO Dr. Adi Zuloff-Shani, discussing the company's innovative approach using non-hallucinogenic psychedelic compounds to address addiction and mental health issues. Clearmind's lead candidate, CMND-100, derived from MEAI, aims to treat alcohol use disorder and is set for clinical trials in early 2023. The company holds seven patent families and has received a patent for using MEAI as an alcohol substitute. The interview addresses the significant market need for effective treatments and outlines plans for an IND application to the FDA for clinical trials.
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