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Chemomab Therapeutics Ltd. American Depositary Share - CMMB STOCK NEWS

Welcome to our dedicated page for Chemomab Therapeutics Ltd. American Depositary Share news (Ticker: CMMB), a resource for investors and traders seeking the latest updates and insights on Chemomab Therapeutics Ltd. American Depositary Share stock.

Chemomab Therapeutics Ltd. (Nasdaq: CMMB) is a clinical-stage biotechnology company focused on the development of innovative therapeutics to treat fibro-inflammatory diseases with significant unmet medical needs. The company's proprietary platform centers on CM-101, a first-in-class monoclonal antibody that targets the protein CCL24, a key regulator of inflammatory and fibrotic pathways in several severe diseases.

CM-101 has demonstrated potential in disrupting the underlying biology of fibrosis through a novel mechanism of action. The company is actively advancing CM-101 through multiple Phase 2 clinical trials aimed at treating rare and life-threatening conditions such as primary sclerosing cholangitis (PSC), non-alcoholic steatohepatitis (NASH), and systemic sclerosis (SSc). In recognition of its innovative approach, CM-101 has been granted Orphan Drug designation in both the U.S. and the European Union, and it recently received Fast Track designation from the FDA for PSC treatment.

Chemomab has reported encouraging preliminary results from these trials, which indicate that CM-101 is safe and effective in interfering with fibrotic and inflammatory pathways. The company has secured robust intellectual property protections for CM-101, with patents granted or pending in major territories worldwide, ensuring proprietary rights for the treatment of multiple indications until at least 2038.

Recent highlights from Chemomab include:

  • Completion of patient enrollment in the Phase 2 PSC trial, with topline data expected mid-2024.
  • Granting of new patents in Brazil, Israel, and Europe that further protect the use of CM-101 in treating liver diseases and other conditions.
  • Publication of peer-reviewed studies validating the role of CCL24 in driving PSC and SSc pathologies, and the potential of CM-101 as a therapeutic intervention.
  • Presentations at major scientific conferences including EASL 2024 and the Gordon Research Conference, showcasing novel translational assays and proteomic profiling studies that support the efficacy of CM-101.

As Chemomab continues to advance its clinical programs and expand its scientific understanding of fibro-inflammatory diseases, it remains committed to addressing the urgent need for effective treatments in these challenging medical areas.

Rhea-AI Summary
Chemomab Therapeutics Ltd. (Nasdaq: CMMB) reports on its study analyzing serum samples and clinical data from systemic sclerosis (SSc) patients, revealing high serum CCL24 levels associated with severe manifestations of the disease, including pulmonary arterial hypertension (PAH). The company's first-in-class monoclonal antibody, CM-101, is designed to neutralize CCL24 and normalize CCL24-driven fibro-inflammatory disease processes.
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Chemomab Therapeutics Ltd. (Nasdaq: CMMB) has been granted Fast Track designation by the FDA for CM-101, a first-in-class monoclonal antibody designed to treat primary sclerosing cholangitis (PSC), a fibrotic liver disease. The Phase 2 SPRING trial is advancing towards completion of enrollment with the top-line readout expected in 2H 2024. CM-101's unique dual anti-fibrotic and anti-inflammatory activity has demonstrated potential disease-modifying effects in preclinical and early clinical studies.
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Chemomab Therapeutics Ltd. (Nasdaq: CMMB) reported on proteomic analyses of Phase 2a liver fibrosis clinical data and oral presentation of proteomic analyses in PSC patients at AASLD's The Liver Meeting® 2023. The data showed consistent and significant improvements in liver-related pathology pathways after treatment with CM-101, a monoclonal antibody designed to neutralize CCL24, a key driver of inflammatory and fibrotic processes underlying PSC and other disorders.
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Chemomab Therapeutics Ltd. (Nasdaq: CMMB) reported strong progress in advancing the CM-101 Phase 2 PSC trial towards completion of enrollment, on track for topline readout in the second half of 2024. The company reiterated that cash reserves are sufficient to fund operations through the end of 2024, with decreasing quarterly cash burn expected to continue.
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Chemomab Therapeutics Ltd. (Nasdaq: CMMB) received a notice from the Nasdaq Listing Qualifications Department stating that the company is not currently in compliance with the $1.00 minimum bid price requirement for continued listing of its American Depositary Shares (ADSs) on the Nasdaq Capital Market. The company has until May 6, 2024, to regain compliance by having the closing bid price of its ADSs meet or exceed $1.00 per ADS for at least 10 consecutive business days. The company's ADSs will continue to trade on the Nasdaq Capital Market under the symbol 'CMMB'.
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Chemomab Therapeutics Ltd. will release its third quarter 2023 financial results and a business update on November 9, 2023 at 8:00 am Eastern Time. Investors can contact the company at IR@chemomab.com for further discussion.
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Chemomab Therapeutics to present at major U.S. scientific conferences in November
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Chemomab Therapeutics announces positive developments for CM-101 in the treatment of primary sclerosing cholangitis (PSC). Phase 2 SPRING trial progressing with topline data expected in H2 2024. CM-101 demonstrates dual anti-fibrotic and anti-inflammatory activity. Positive results from Phase 2a trial in NASH patients. Promising potential as a disease-modifying therapy for PSC.
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FAQ

What is the current stock price of Chemomab Therapeutics Ltd. American Depositary Share (CMMB)?

The current stock price of Chemomab Therapeutics Ltd. American Depositary Share (CMMB) is $2.13 as of January 3, 2025.

What is the market cap of Chemomab Therapeutics Ltd. American Depositary Share (CMMB)?

The market cap of Chemomab Therapeutics Ltd. American Depositary Share (CMMB) is approximately 41.2M.

What is Chemomab Therapeutics Ltd.?

Chemomab Therapeutics Ltd. is a clinical-stage biotechnology company that focuses on developing innovative therapeutics for fibro-inflammatory diseases with high unmet medical needs.

What is CM-101?

CM-101 is a first-in-class monoclonal antibody developed by Chemomab that targets the protein CCL24 to disrupt inflammatory and fibrotic pathways in severe diseases.

What diseases is CM-101 being tested for?

CM-101 is currently in Phase 2 clinical trials for primary sclerosing cholangitis (PSC), non-alcoholic steatohepatitis (NASH), and systemic sclerosis (SSc).

Has CM-101 received any special designations from regulatory authorities?

Yes, CM-101 has been granted Orphan Drug designation in the U.S. and the European Union, and it recently received Fast Track designation from the FDA for the treatment of PSC.

When are the results from the Phase 2 PSC trial expected?

The topline results from the Phase 2 trial for primary sclerosing cholangitis (PSC) are expected to be released by mid-2024.

What recent achievements has Chemomab announced?

Recent achievements include the completion of patient enrollment in the Phase 2 PSC trial, new patents granted in Brazil, Israel, and Europe, and positive findings published in peer-reviewed journals.

What makes CM-101 unique?

CM-101 targets the soluble protein CCL24, which plays a pivotal role in fibrosis and inflammation. Its dual mechanism of action makes it a novel therapeutic candidate for fibro-inflammatory diseases.

What is the significance of the new patents granted to Chemomab?

The new patents strengthen the intellectual property protections for CM-101, covering its use in treating liver diseases and other conditions, and extending proprietary rights until 2038.

Where has Chemomab presented its research?

Chemomab has presented its research at major scientific conferences, including EASL 2024 and the Gordon Research Conference, where it showcased translational assays and proteomic profiling studies.

How does CM-101 work?

CM-101 works by neutralizing CCL24, which disrupts the inflammatory and fibrotic pathways central to several fibro-inflammatory diseases, thereby offering potential therapeutic benefits.
Chemomab Therapeutics Ltd. American Depositary Share

Nasdaq:CMMB

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41.20M
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0.86%
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