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CollPlant Biotechnologies Ltd (NASDAQ: CLGN) is a pioneering company in regenerative and aesthetic medicine, specializing in the 3D bioprinting of tissues and organs and medical aesthetics. The company's core technology is its recombinant human collagen (rhCollagen), produced through proprietary plant-based genetic engineering. CollPlant's innovative products address diverse fields of tissue repair, aesthetics, and organ manufacturing, marking a new era in regenerative medicine.
CollPlant's flagship rhCollagen bioink product line is optimized for 3D bioprinting applications, including drug discovery, tissue testing, and the development of transplantable tissues and organs. The company's unique Vergenix™ line includes a soft tissue repair matrix for tendinopathy treatment and a wound repair matrix that promotes rapid healing of acute and chronic wounds.
In the medical aesthetics market, CollPlant is advancing its regenerative breast implants and dermal fillers. The company has formed strategic partnerships, including a notable collaboration with AbbVie for the development of dermal and soft tissue fillers, triggering milestone payments and potential future royalties.
Recent achievements include the initiation of pre-clinical trials for regenerative breast implants and progress in large-animal studies demonstrating tissue regeneration and safety. In addition, CollPlant's advanced bioinks are facilitating the bio-fabrication of human tissues and organs in collaboration with industry leaders.
Financially, CollPlant reported significant revenue increases due to milestone payments and product sales, although it continues to invest in research and development to maintain its leading position in the market. The company's cash and cash equivalents provide a robust runway for at least two years of operation, supporting ongoing and future projects.
CollPlant's commitment to sustainability is reflected in its plant-based production process and adherence to Environmental, Social, and Governance (ESG) principles. The company joined the United Nations Global Compact to further its sustainable corporate governance goals.
CollPlant (Nasdaq: CLGN) announced positive results from a large animal study of its recombinant human collagen (rhCollagen)-based 3D bioprinted regenerative breast implants. The study demonstrated successful tissue regeneration with no adverse reactions, positioning these implants as a safer alternative for the $2.5 billion global breast implant market. The company plans to initiate a follow-up study in 2023 with commercial-size implants to pave the way for human trials and commercialization, focusing on overcoming safety challenges associated with traditional silicone implants.
CollPlant (Nasdaq: CLGN) has launched Collink.3D™ 50L, a recombinant human collagen-based bioink in powder form, enhancing flexibility for a variety of 3D bioprinting applications such as drug discovery and tissue engineering. This product aims to provide biopharma and academic customers with an animal-free alternative that offers improved bio-functionality and safety. It expands CollPlant's existing portfolio of bioinks and is designed for easy reconstitution for specific applications. The new bioink seeks to streamline product development processes and reduce costs.
CollPlant Biotechnologies (Nasdaq: CLGN) reported Q3 2022 financial results, showing GAAP revenues of $109,000, a decline from $140,000 in Q3 2021. The net loss increased to $4.4 million, or $0.40 per share, compared to $3.1 million, or $0.29 per share, in the prior year. The company maintains a strong balance sheet with $33 million in cash. Key developments include partnerships with AbbVie and Tel Aviv University for dermal fillers and a 3D bioprinted intestine model. CollPlant's operating expenses rose due to increased R&D and personnel costs.
CollPlant (NASDAQ: CLGN) announced a collaboration with Tel Aviv University and Sheba Medical Center to co-develop a 'Gut-on-a-Chip' tissue model aimed at enhancing treatment for ulcerative colitis. The agreement entails that CollPlant will finance the development and secure exclusive rights for manufacturing and commercialization. This 3D bioprinted intestine model combines human recombinant collagen with innovative biomaterials, promising progress in personalized medicine and drug discovery while potentially reducing reliance on animal testing.
CollPlant (Nasdaq: CLGN) has launched Collink.3D™ 90, a recombinant human collagen-based bioink designed for versatile 3D bioprinting applications, including both soft and hard tissues. This product demonstrates increased mechanical properties and faster human cell migration compared to a widely used hydrogel. The introduction of this bioink aligns with the company's strategic goal to enhance its portfolio of rhCollagen-based bioinks for biopharma and academic markets, representing a significant expansion in the tissue engineering field.
CollPlant Biotechnologies (NASDAQ: CLGN), a leader in regenerative medicine, announced a presentation by Deputy CEO Eran Rotem at the Canaccord Genuity MedTech Forum on November 17, 2022, at 2:00 p.m. ET. The presentation will overview the company's innovative human-collagen based technologies aimed at tissue regeneration and organ manufacturing. CollPlant has established agreements with Allergan and 3D Systems for product development in dermal fillers and regenerative matrices. Attendees can request one-on-one meetings with the company during the event.
CollPlant Biotechnologies (Nasdaq: CLGN) will be presenting an overview at the Dawson James 7th Annual Small Cap Growth Conference in Jupiter, Florida. The presentation will be led by Deputy CEO & CFO Eran Rotem on October 12 from 14:00-14:25 PM ET. Investors attending can request one-on-one meetings through conference coordinators. CollPlant specializes in regenerative and aesthetic medicine, focusing on 3D bioprinting technologies using proprietary recombinant human collagen to address tissue repair and organ manufacturing.
CollPlant (NASDAQ: CLGN) announced its participation at the International Conference on Biofabrication in Tuscany, Italy, from September 25 to 28, 2022. The company will present on "Recombinant Human Collagen-based Bioinks for Biofabrication and Modeling Applications" on September 28 during the symposium from 9:00 AM to 10:30 AM CET. CollPlant focuses on innovative solutions in tissue regeneration and organ manufacturing using its proprietary rhCollagen technology, and will feature an exhibition booth at the conference.
CollPlant Biotechnologies (Nasdaq: CLGN) announced participation in upcoming investor conferences. Deputy CEO and CFO Eran Rotem will engage with investors at the HC Wainwright 24th Annual Global Investment Conference on September 12-13 and the Alliance Global Partners MedTech Conference on September 21. CollPlant focuses on innovative collagen-based technologies for tissue regeneration and organ manufacturing. The company has also partnered with Allergan and 3D Systems to advance its product offerings in aesthetic and regenerative medicine.
CollPlant Biotechnologies (NASDAQ: CLGN) reported its Q2 2022 financial results, revealing a GAAP revenue of $66,000, down from $691,000 the previous year, primarily due to decreased BioInk and Vergenix product sales. The company reported a net loss of $4.3 million, or $0.39 per share. Notably, CollPlant is advancing its co-development agreement with AbbVie for dermal fillers and is on track for large animal studies of its 3D bioprinted regenerative breast implant. Cash and equivalents stood at $36 million as of June 30, 2022, reflecting a strong balance sheet.
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