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Cognition Therapeutics, Inc. - CGTX STOCK NEWS

Welcome to our dedicated page for Cognition Therapeutics news (Ticker: CGTX), a resource for investors and traders seeking the latest updates and insights on Cognition Therapeutics stock.

Cognition Therapeutics, Inc. (NASDAQ: CGTX) is a clinical-stage biopharmaceutical company based in Pittsburgh, Pennsylvania. Established in 2007, the company is dedicated to discovering and developing small-molecule therapeutics aimed at treating age-related degenerative diseases and disorders of the central nervous system and retina.

At the heart of Cognition Therapeutics' innovation is its proprietary biology and chemistry platforms, which are utilized to identify novel drug targets and create disease-modifying therapies. The company's flagship product candidate, CT1812, is an orally administered small-molecule antagonist designed to breach the blood-brain barrier. CT1812 binds selectively to the S2R complex, potentially offering a unique therapeutic approach for patients.

Current Projects and Achievements:

  • CT1812 is currently being evaluated in Phase 2 clinical trials for conditions such as Alzheimer’s disease, dementia with Lewy bodies (DLB), and dry age-related macular degeneration (dry AMD).
  • Recent 2023 milestones include completing enrollment for the SHINE Study in mild-to-moderate Alzheimer's disease and initiating new clinical studies for early Alzheimer's and dry AMD.
  • The SHIMMER study for mild-to-moderate DLB has also reached its target enrollment, with top-line results anticipated in the latter half of 2024.

The company has made significant strides in advancing its clinical programs. In 2023, the FDA approved the first disease-modifying biologics for Alzheimer’s disease, which has rejuvenated research and investment in this critical area. Cognition Therapeutics is leveraging this momentum in its ongoing research and clinical trials.

Financial Overview:

For the year ending December 31, 2023, Cognition Therapeutics reported cash and cash equivalents of approximately $29.9 million. Additional capital from a March 2024 offering has bolstered their financial position, providing the company with sufficient funds to support operations and capital expenditures through May 2025.

Research and development expenses for 2023 were $37.2 million, an increase from $30.3 million in 2022, reflecting higher costs associated with Phase 2 trials and personnel. General and administrative expenses remained relatively stable at $13.5 million.

The company continues to foster collaborations and partnerships to advance its scientific goals. Notably, the SHIMMER study is supported by a significant grant from the National Institute on Aging (NIA), totaling approximately $30 million.

For ongoing updates and detailed information about Cognition Therapeutics, visit their website at cogrx.com.

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Cognition Therapeutics, Inc. (CGTX) announced that its president and CEO will present at the TD Cowen 44th Annual Health Care Conference to discuss the company's pipeline progress and recent achievements.
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Cognition Therapeutics, Inc. (NASDAQ: CGTX) announced new findings that provide insight into the biology of Alzheimer's disease. The research, conducted by collaborators at the University of Edinburgh, revealed the role of the σ-2 receptor in regulating Aβ oligomer binding. The study utilized high-resolution microscopy techniques to analyze protein-protein interactions in brain samples from individuals with Alzheimer's disease. The results indicate that Aβ oligomers are proximate to certain receptor proteins on the synapse surface, which may form a complex. Additionally, the study confirmed that CT1812, Cognition's lead product candidate, causes the removal of Aβ oligomers from synapses, offering a potential new mechanism to fight Alzheimer's disease progression.
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Cognition Therapeutics, Inc. (Nasdaq: CGTX) announced the anticipation of topline data from Phase 2 SHINE trial in patients with mild-to-moderate Alzheimer's disease and Phase 2 SHIMMER trial in mild-to-moderate dementia with Lewy bodies in 2024.
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Cognition Therapeutics, Inc. (Nasdaq: CGTX) releases its seventh Conversations video podcast episode discussing the results from the Phase 2 SEQUEL study on CT1812's effects on synaptic function in Alzheimer’s Disease. Dr. Anthony Caggiano moderates a discussion with leading experts, highlighting the positive impact of CT1812 treatment on synaptic function in adults with mild-to-moderate Alzheimer’s disease, as presented at the CTAD conference.
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Cognition Therapeutics, Inc. (NASDAQ: CGTX) presents in vivo preclinical results at the Society for Neuroscience’s annual meeting, highlighting the role of sigma-2 receptor modulators in Alzheimer's and Parkinson’s diseases. The data reveals the effect of two chemically distinct σ-2 receptor modulators on gene and protein expression in mouse and rat models of the diseases. These findings support the continued discovery and development of candidates targeting this therapeutic area.
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Cognition Therapeutics, Inc. completed enrollment in the Phase 2 SHINE study of CT1812 for Alzheimer's disease, with top-line results expected in mid-2024. Initial results showed a slowing of cognitive decline and positive safety profile.
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Cognition Therapeutics, Inc. reported financial results for Q3 2023, with cash and cash equivalents of $33.0 million. The company initiated clinical site enrollment for the Phase 2 START trial for Alzheimer's disease and began dosing in the MAGNIFY trial for dry age-macular degeneration. The CEO expects to report topline results from the Phase 2 SHINE trial in mid-2024 and data from the Phase 2 SHIMMER trial in 2024.
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Cognition Therapeutics presents Phase 2 study design of START study at CTAD conference. The study assesses CT1812 in individuals with early Alzheimer’s disease. Combination therapies and the potential benefits of CT1812 are discussed. Clinical data supports CT1812's potential benefits. The START study is actively underway with screening at multiple clinical sites.
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Cognition Therapeutics presents EEG findings from Phase 2 SEQUEL study at CTAD conference
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Cognition Therapeutics releases video podcast on dry AMD treatment landscape
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FAQ

What is the current stock price of Cognition Therapeutics (CGTX)?

The current stock price of Cognition Therapeutics (CGTX) is $0.6301 as of December 20, 2024.

What is the market cap of Cognition Therapeutics (CGTX)?

The market cap of Cognition Therapeutics (CGTX) is approximately 25.1M.

What does Cognition Therapeutics, Inc. specialize in?

Cognition Therapeutics specializes in discovering and developing small-molecule therapeutics for age-related degenerative diseases and central nervous system disorders.

What is CT1812?

CT1812 is Cognition Therapeutics' lead product candidate, designed to cross the blood-brain barrier and bind selectively to the S2R complex, with potential applications in treating Alzheimer's disease, DLB, and dry AMD.

What recent achievements has Cognition Therapeutics made?

Recent achievements include completing enrollment for the Phase 2 SHINE Study in Alzheimer’s disease, initiating new studies for early Alzheimer’s and dry AMD, and reaching target enrollment for the SHIMMER study in DLB.

How is Cognition Therapeutics funded?

Cognition Therapeutics is funded through a mix of private investments, public offerings, and grants. The company reported cash and cash equivalents of $29.9 million as of December 31, 2023, with additional capital from a March 2024 offering.

What are the company's main areas of research?

The company focuses on developing therapies for disorders of the central nervous system and retina, particularly targeting Alzheimer’s disease, dementia with Lewy bodies (DLB), and dry age-related macular degeneration (dry AMD).

Where is Cognition Therapeutics located?

Cognition Therapeutics is headquartered in Pittsburgh, Pennsylvania.

What are the financial highlights for Cognition Therapeutics in 2023?

In 2023, the company reported research and development expenses of $37.2 million and general and administrative expenses of $13.5 million. They have secured sufficient funds to support operations through May 2025.

How does CT1812 work?

CT1812 is designed to penetrate the blood-brain barrier and bind to the S2R complex, which is involved in regulating cellular processes disrupted in neurodegenerative diseases.

What are some key milestones expected in 2024?

Key milestones for 2024 include the top-line readout from the Phase 2 SHINE study in Alzheimer’s disease and the SHIMMER study in DLB.

How can I stay updated on Cognition Therapeutics’ progress?

You can stay updated by visiting the Cognition Therapeutics website at https://cogrx.com and following their latest news and press releases.

Cognition Therapeutics, Inc.

Nasdaq:CGTX

CGTX Rankings

CGTX Stock Data

25.08M
41.32M
0.54%
24.53%
2.03%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States of America
PITTSBURGH