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ContraFect Corporation (CFRX) is a pioneering biotechnology company dedicated to combating life-threatening infectious diseases, particularly those prevalent in hospital settings. Given the alarming rise of drug-resistant and newly-emerging pathogens, hospital-acquired infections have become the fourth leading cause of death in the United States, following heart disease, cancer, and stroke.
ContraFect's core business revolves around the development and commercialization of protein and antibody therapeutic products. The company leverages its innovative lysin and monoclonal antibody platforms to target conserved regions of bacteria and viruses. Lysins are enzymes produced during the life cycle of bacteriophages, which are viruses that infect and kill bacteria. This unique approach positions ContraFect at the forefront of antimicrobial therapy, especially against multi-drug resistant pathogens.
Recent achievements have solidified ContraFect's leadership in this critical field. The company has made significant strides in advancing its therapeutic candidates through various stages of clinical development. These efforts are underscored by strategic partnerships and collaborations aimed at accelerating the discovery, acquisition, and development of novel protein and antibody products.
Financially, ContraFect remains committed to transparency and growth. The latest quarterly results reflect the company's robust financial health and strategic investments in research and development. These investments are crucial for maintaining its competitive edge and ensuring the successful commercialization of its therapeutic products.
ContraFect's dedication to addressing life-threatening infectious diseases is evident in its ongoing projects and future plans. The company continues to explore new avenues for therapeutic discovery, aiming to deliver first-in-class treatments that can effectively manage and eradicate drug-resistant infections.
For more detailed updates, follow ContraFect on Twitter @ContraFectCorp and LinkedIn, or contact their investor relations team.
ContraFect Corporation (Nasdaq: CFRX), a late clinical-stage biotechnology company, announced that CEO Roger Pomerantz will participate in a fireside chat at the Maxim Group 2022 Virtual Growth Conference from March 28–30, 2022. The chat, scheduled for March 28 at 2:00 PM ET, will be led by Jason McCarthy, Ph.D. Investors can register to view the talk here. ContraFect focuses on developing direct lytic agents (DLAs) to combat antibiotic-resistant infections, with a notable candidate, exebacase, undergoing pivotal Phase 3 trials.
ContraFect Corporation (Nasdaq: CFRX) announced that Dr. Roger Pomerantz, the company's President and CEO, will participate in a fireside chat at the SVB Leerink 11th Annual Global Healthcare Conference occurring virtually from February 14-18, 2022. The chat is scheduled for February 17, 2022, at 10:00 AM ET. Investors can access a live webcast on ContraFect's website, which will also be available as an archive for a limited time. The company focuses on developing direct lytic agents to combat antibiotic-resistant infections, addressing a critical public health challenge.
ContraFect Corporation (Nasdaq: CFRX) has received a new contract award from the Cystic Fibrosis Foundation to explore the utility of exebacase in treating MRSA lung infections in cystic fibrosis patients. This 12-month program will assess the in vitro activity of the drug against bacterial specimens from patients. The prevalence of MRSA in cystic fibrosis has increased significantly, presenting a critical health risk. ContraFect retains global rights to exebacase and its therapeutic pipeline, focusing on addressing the urgent needs of antibiotic-resistant infections.
ContraFect Corporation (Nasdaq: CFRX) announced a significant case report showcasing its investigational drug exebacase as a potential adjunctive therapy for severe MRSA infections in pediatric patients. Published in Clinical Infectious Diseases, the report details a case involving a 5-month-old infant with life-threatening MRSA bacteremia. Following standard treatments, the patient received exebacase under FDA authorization, leading to sterile blood cultures and clinical improvement. This single case suggests the need for further studies to assess exebacase's efficacy in treating MRSA in children.
ContraFect Corporation (CFRX) announced its third quarter 2021 financial results, reporting a net loss of $5.3 million, or $(0.13) per share, compared to a net income of $3.4 million, or $0.12 per share, in Q3 2020. R&D expenses rose to $8.7 million from $4.7 million year-over-year due to increased clinical study costs. The company continues to focus on its Phase 3 DISRUPT study for exebacase, which targets Staph aureus bloodstream infections, with nearly 60 active clinical sites. Interim analysis is anticipated in H1 2022.
ContraFect Corporation (Nasdaq: CFRX) announced promising data for its direct lytic agents, lysin CF-370 and amurin peptide AM1, which exhibit in vitro activity against prevalent Gram-negative pathogens linked to lung infections in cystic fibrosis patients. Presented at the North American Cystic Fibrosis Conference, these agents show potential efficacy against multi-drug resistant strains, including Pseudomonas aeruginosa. With limited existing treatment options, the results highlight the need for innovative therapies in this patient population.
ContraFect Corporation (Nasdaq: CFRX), a biotechnology company, announces a poster presentation at the North American Cystic Fibrosis Conference (NACFC) from November 2-5, 2021. The poster, titled 'Direct Lytic Agents (DLAs), a Novel Family of Antimicrobial Agents, Exert Potent in vitro Bactericidal Activity Against Gram-negative Pathogens', focuses on DLAs' effectiveness against pathogens causing pulmonary infections in Cystic Fibrosis patients. The presentation by Dr. Raymond Schuch will detail the promise of DLAs in combating antibiotic-resistant infections. The poster will later be available on their website.
ContraFect Corporation (Nasdaq:CFRX) announced promising Phase 2 results of exebacase for treating Staphylococcus aureus bacteremia, presented at IDWeek 2021. The data indicates that 94.3% of patients receiving exebacase alongside standard antibiotics experienced symptom resolution, compared to 87.9% in the control group. Median time to resolution was significantly reduced to 3 days from 6 days. Exebacase may serve as a new treatment modality for serious bloodstream infections, including MRSA, where current options are limited. The company is advancing to a pivotal Phase 3 trial for further evaluation.
ContraFect Corporation (CFRX) announced the presentation of positive clinical data on exebacase at IDWeek 2021. A completed Phase 2 study demonstrated that exebacase significantly improved clinical responder rates by nearly 43 percentage points compared to standard-of-care antibiotics for Staphylococcus aureus bacteremia. Additionally, exebacase showed a 21 percentage point reduction in 30-day mortality. Exebacase is currently under evaluation in the pivotal Phase 3 DISRUPT study, potentially establishing it as a first-in-class treatment for this serious condition.
ContraFect Corporation (Nasdaq: CFRX) has announced that CEO Roger Pomerantz will participate in a fireside chat at the Cantor Global Virtual Healthcare Conference from September 27 to 30, 2021, specifically on September 29 at 11:20 AM ET. The event will be webcast live and archived for later access on the company’s website. ContraFect is focused on developing direct lytic agents for treating antibiotic-resistant infections, targeting pathogens like MRSA and P. aeruginosa, with its lead candidate, exebacase, currently in late-stage clinical trials.
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