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C4 Therapeutics, Inc. - CCCC STOCK NEWS

Welcome to our dedicated page for C4 Therapeutics news (Ticker: CCCC), a resource for investors and traders seeking the latest updates and insights on C4 Therapeutics stock.

Company Overview

C4 Therapeutics, Inc. (NASDAQ: CCCC) is a clinical-stage biopharmaceutical company focused on harnessing targeted protein degradation to pioneer a new generation of medicines. Leveraging advanced drug discovery techniques, C4 Therapeutics seeks to address diseases that are resistant to conventional treatments by eliminating harmful proteins through the body’s natural ubiquitin-proteasome system. The company is recognized for its scientific ingenuity and its commitment to transforming patient care across difficult-to-treat oncology indications.

Innovative Technology and Platforms

The company’s core approach centers on selective and rapid protein degradation using proprietary platforms. The TORPEDO® platform enables the efficient design and optimization of small-molecule medicines. This platform, along with their advanced degrader technologies, facilitates precise targeting of pathogenic proteins and offers a novel mechanism of action that distinguishes their molecules from traditional inhibitors. By employing these cutting-edge tools, C4 Therapeutics is positioned to overcome challenges such as drug resistance and the targeting of previously "undruggable" proteins.

Clinical Pipeline

C4 Therapeutics has built a robust pipeline of oral degrader candidates that are advancing through clinical trials. Notable assets include:

  • Cemsidomide: An oral degrader targeting IKZF1/3 designed for potential application in hematologic malignancies such as multiple myeloma and non-Hodgkin’s lymphoma. Its innovative mechanism aims to improve patient outcomes by addressing key oncogenic transcription factors.
  • CFT1946: An orally bioavailable degrader targeting BRAF V600X mutant proteins, developed for solid tumors. This candidate is engineered to overcome common resistance mechanisms and has demonstrated promising preclinical and early clinical data.
  • CFT8919: Focused on targeting EGFR mutations, particularly the oncogenic L858R variant, this candidate is being developed to address non-small cell lung cancer. It exemplifies the company’s commitment to expanding its impact in both regional and global markets through strategic partnerships.

Collaborations and Strategic Partnerships

C4 Therapeutics enhances its technological and clinical capabilities through strategic collaborations with prominent industry players. Its partnerships with Biogen, Merck, MKDG, and Betta Pharmaceuticals underpin its expertise in drug discovery and clinical development. These alliances not only bolster the company’s scientific credibility but also provide additional validation of its targeted protein degradation approach.

Market Position and Value Proposition

In the competitive landscape of biopharmaceutical innovation, C4 Therapeutics distinguishes itself with a focused strategy on targeted protein degradation. The company offers a differentiated value proposition by aiming to rapidly eliminate disease-driving proteins, thereby potentially overcoming the limitations of standard small-molecule inhibitors. This approach underlines its commitment to developing therapies for patient populations with high unmet medical needs.

Scientific Rigor and Industry Expertise

Emphasizing transparency and scholarly integrity, C4 Therapeutics integrates rigorous scientific research with comprehensive clinical validation. Its communication strategy, supported by detailed clinical studies and data presentations at major scientific venues, reflects its deep expertise and reinforces the trustworthiness of its research methodologies.

Conclusion

C4 Therapeutics stands as a prime example of innovation in the realm of targeted protein degradation, bridging cutting-edge science with clinical application. For investors and industry analysts, the company’s strategic focus on developing orally bioavailable small-molecule degraders offers a unique insight into the evolving therapeutic landscape aimed at overcoming challenging diseases through novel mechanisms of action.

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C4 Therapeutics, Inc. reports positive clinical data for CFT7455 in treating relapsed/refractory multiple myeloma and non-Hodgkin’s lymphomas. Encouraging PK and PD data for CFT1946 targeting solid tumors. Financially, revenue decreased in 2023 but the company remains well-capitalized with cash runway expected into 2027.
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C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC) announced its 2024 priorities, including multiple clinical updates, a 30% workforce reduction, and a cash runway into 2027. The company also reported unaudited cash, cash equivalents, and marketable securities totaling approximately $330 million as of January 5, 2024. C4T has received additional capital of approximately $107 million and will present at the 42nd Annual J.P. Morgan Healthcare Conference on January 11.
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C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC) announced the closing of a $25 million stock purchase agreement with Betta Pharmaceuticals Co. Ltd (300558.SZ), a leading pharmaceutical company in China. The investment was completed at $4.49 per share, representing a 25% premium over the 60-trading-day volume weighted average.
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C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC) will present at the 42nd Annual J.P. Morgan Healthcare Conference on January 11, 2024, to discuss advancements in targeted protein degradation science and the development of new small-molecule medicines.
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C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC) presents promising clinical data from Phase 1 trial of CFT7455 for multiple myeloma and non-Hodgkin’s lymphomas
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C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC) has entered into an exclusive license and collaboration agreement with Merck to develop degrader-antibody conjugates (DACs) for cancer treatment. C4T will receive a $10 million upfront payment and is eligible for milestone payments totaling approximately $600 million, as well as tiered royalties on future sales. Merck has the option to extend the collaboration to include three additional targets, potentially resulting in up to approximately $2.5 billion in potential payments across the entire collaboration.
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C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC) to present new Phase 1 dose escalation data for relapsed refractory multiple myeloma from the ongoing Phase 1/2 clinical trial of CFT7455, a MonoDAC™ degrader of IKZF1/3, for the potential treatment of relapsed/refractory multiple myeloma and relapsed/refractory non-Hodgkin’s lymphoma.
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C4 Therapeutics, Inc. (C4T) (Nasdaq: CCCC) appoints Owen Hughes, an accomplished life sciences executive, to its board of directors. Hughes brings nearly three decades of experience in investing, operations, and corporate governance. He is expected to leverage his expertise to strategically advance the company's portfolio of novel degrader medicines, potentially transforming disease treatment.
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C4 Therapeutics reported financial results for Q3 2023, with total revenue of $11.1 million, compared to $6.8 million in Q3 2022. The company's cash, cash equivalents, and marketable securities totaled $246.4 million as of September 30, 2023, providing runway into the second half of 2025. The ongoing Phase 1/2 trials of CFT7455 and CFT1946 will be prioritized, while CFT8634 will not advance due to insufficient single agent efficacy in synovial sarcoma and SMARCB1-null tumors. The company also provided updates on its other clinical trials and collaborations.
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FAQ

What is the current stock price of C4 Therapeutics (CCCC)?

The current stock price of C4 Therapeutics (CCCC) is $2.36 as of March 7, 2025.

What is the market cap of C4 Therapeutics (CCCC)?

The market cap of C4 Therapeutics (CCCC) is approximately 167.5M.

What is the primary focus of C4 Therapeutics?

C4 Therapeutics focuses on harnessing targeted protein degradation science to develop novel therapies for challenging diseases, particularly in oncology.

How does C4 Therapeutics' technology work?

The company employs proprietary platforms like TORPEDO® that efficiently design small-molecule degraders to eliminate disease-causing proteins through the natural ubiquitin-proteasome system.

What are the key assets in C4 Therapeutics' pipeline?

Key pipeline assets include cemsidomide for hematologic malignancies, CFT1946 for solid tumors driven by BRAF mutations, and CFT8919 targeting EGFR mutations in non-small cell lung cancer.

How do collaborations enhance the company’s capabilities?

Strategic partnerships with companies like Biogen, Merck, and Betta Pharmaceuticals validate C4 Therapeutics' technology and provide complementary expertise in drug development and clinical validation.

What competitive advantage does C4 Therapeutics offer?

By focusing on targeted protein degradation, the company aims to overcome drug resistance and address previously undruggable targets, positioning itself uniquely in the evolving therapeutic landscape.

How does C4 Therapeutics ensure scientific credibility?

The company maintains rigorous clinical studies, data-driven research, and transparent reporting at major scientific meetings, which underscores its expertise and commitment to patient care.
C4 Therapeutics, Inc.

Nasdaq:CCCC

CCCC Rankings

CCCC Stock Data

167.54M
57.89M
11.42%
91.58%
13.15%
Biotechnology
Biological Products, (no Disgnostic Substances)
Link
United States
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