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Carisma Therapeutics Announces Upcoming Presentations at SITC 2024

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Carisma Therapeutics Inc. (Nasdaq: CARM), a clinical-stage biopharmaceutical company, has announced its upcoming poster presentations at the Society for Immunotherapy of Cancer (SITC) 2024 in Houston, Texas, from November 6-10. The company will present two posters:

1. Pre-clinical efficacy of a novel anti-GPC3 in vivo CAR-M for hepatocellular carcinoma (Publication Number: 329)

2. A Phase 1, First-in-Human study of autologous monocytes engineered to express an anti-HER2 chimeric antigen receptor (CAR) in participants with HER2 overexpressing solid tumors (Publication Number: 659)

Both presentations are scheduled for Friday, November 8, 2024, at the Exhibit Halls A B George R. Brown Convention Center. The posters will be available on Carisma's website in the 'Publications' section following the start of the poster session.

Carisma Therapeutics Inc. (Nasdaq: CARM), una società biofarmaceutica in fase clinica, ha annunciato le sue prossime presentazioni di poster alla Società per l'Immunoterapia del Cancro (SITC) 2024 a Houston, Texas, dal 6 al 10 novembre. L'azienda presenterà due poster:

1. Efficacia pre-clinica di un nuovo CAR-M anti-GPC3 in vivo per il carcinoma epatocellulare (Numero di Pubblicazione: 329)

2. Uno studio di Fase 1, Primo negli Umani, di monociti autologhi ingegnerizzati per esprimere un recettore antigenico chimerico (CAR) anti-HER2 in partecipanti con tumori solidi che sovraesprimono HER2 (Numero di Pubblicazione: 659)

Entrambe le presentazioni sono programmate per venerdì 8 novembre 2024, presso i Padiglioni Espositivi A B del George R. Brown Convention Center. I poster saranno disponibili sul sito web di Carisma nella sezione 'Pubblicazioni' al termine della sessione poster.

Carisma Therapeutics Inc. (Nasdaq: CARM), una empresa biofarmacéutica en etapa clínica, ha anunciado sus próximas presentaciones de carteles en la Sociedad para la Inmunoterapia del Cáncer (SITC) 2024 en Houston, Texas, del 6 al 10 de noviembre. La compañía presentará dos carteles:

1. Eficacia preclínica de un novedoso CAR-M anti-GPC3 en vivo para el carcinoma hepatocelular (Número de Publicación: 329)

2. Un estudio de Fase 1, Primero en Humanos, de monócitos autólogos diseñados para expresar un receptor antigénico quimérico (CAR) anti-HER2 en participantes con tumores sólidos que sobreexpresan HER2 (Número de Publicación: 659)

Ambas presentaciones están programadas para el viernes 8 de noviembre de 2024, en los Salones de Exposición A B del Centro de Convenciones George R. Brown. Los carteles estarán disponibles en el sitio web de Carisma en la sección 'Publicaciones' tras el inicio de la sesión de carteles.

Carisma Therapeutics Inc. (Nasdaq: CARM)는 임상 단계의 생명공학 회사로, 텍사스주 휴스턴에서 11월 6일부터 10일까지 열리는 암 면역 치료 학회(SITC) 2024에서 포스터 발표를 할 예정이라고 발표했습니다. 이 회사는 두 개의 포스터를 발표할 것입니다:

1. 간세포암에 대한 새로운 항-GPC3 인 비보 CAR-M의 전임상 효능 (발표 번호: 329)

2. HER2 과발현 고형 종양 환자에서 항-HER2 키메라 항원 수용체(CAR)를 발현하도록 설계된 자가 단핵구의 1상, 최초의 인간 연구 (발표 번호: 659)

두 발표는 2024년 11월 8일 금요일에 조지 R. 브라운 컨벤션 센터의 A B 전시 홀에서 진행됩니다. 포스터는 포스터 세션 시작 후 Carisma의 웹사이트 '출판물' 섹션에서 확인할 수 있습니다.

Carisma Therapeutics Inc. (Nasdaq: CARM), une entreprise biopharmaceutique en phase clinique, a annoncé ses prochaines présentations d'affiches lors de la Société pour l'Immunothérapie du Cancer (SITC) 2024 à Houston, Texas, du 6 au 10 novembre. L'entreprise présentera deux affiches :

1. Efficacité préclinique d'un nouveau CAR-M anti-GPC3 in vivo pour le carcinome hépatocellulaire (Numéro de publication : 329)

2. Une étude de Phase 1, première chez l'homme, de monocites autologues conçues pour exprimer un récepteur anticorps chimérique (CAR) anti-HER2 chez des participants avec des tumeurs solides surexprimant HER2 (Numéro de publication : 659)

Les deux présentations sont programmées pour le vendredi 8 novembre 2024, dans les halls d'exposition A B du George R. Brown Convention Center. Les affiches seront disponibles sur le site Web de Carisma dans la section 'Publications' après le début de la session d'affiches.

Carisma Therapeutics Inc. (Nasdaq: CARM), ein biopharmazeutisches Unternehmen in der klinischen Entwicklungsphase, hat seine kommenden Posterpräsentationen auf der Gesellschaft für Immuntherapie bei Krebs (SITC) 2024 in Houston, Texas, vom 6. bis 10. November angekündigt. Das Unternehmen wird zwei Poster präsentieren:

1. Präklinische Wirksamkeit eines neuartigen in vivo CAR-M gegen GPC3 bei hepatocellulärem Karzinom (Publikationsnummer: 329)

2. Eine Phase-1-Studie, Erste beim Menschen, von autologen Monozyten, die darauf ausgelegt sind, einen anti-HER2 chimären Antigenrezeptor (CAR) bei Teilnehmern mit HER2-überexprimierenden soliden Tumoren zu exprimieren (Publikationsnummer: 659)

Beide Präsentationen sind für Freitag, den 8. November 2024, in den Ausstellungsräumen A B des George R. Brown Convention Centers geplant. Die Poster sind nach Beginn der Postersitzung auf der Website von Carisma im Abschnitt 'Veröffentlichungen' verfügbar.

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PHILADELPHIA, Oct. 4, 2024 /PRNewswire/ -- Carisma Therapeutics Inc. (Nasdaq: CARM) ("Carisma" or the "Company"), a clinical-stage biopharmaceutical company focused on discovering and developing innovative immunotherapies, today announced its upcoming poster presentations at the Society for Immunotherapy of Cancer (SITC), taking place in Houston, Texas, November 6 -10, 2024.

Details on the poster presentations at SITC 2024 are below:

Title: Pre-clinical efficacy of a novel anti-GPC3 in vivo CAR-M for hepatocellular carcinoma
Publication Number: 329
Session Date & Time: Friday, Nov. 8, 2024
Location: Exhibit Halls A B George R. Brown Convention Center

Title: A Phase 1, First-in-Human study of autologous monocytes engineered to express an anti-HER2 chimeric antigen receptor (CAR) in participants with HER2 overexpressing solid tumors
Publication Number: 659
Session Date & Time: Friday, Nov. 8, 2024
Location: Exhibit Halls A B George R. Brown Convention Center

The posters presented at SITC 2024 will be available online in the "Publications" section of Carisma's website at https://carismatx.com/technology/publications/ following the start of the poster session.

About Carisma Therapeutics

Carisma Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on utilizing our proprietary macrophage and monocyte cell engineering platform to develop transformative immunotherapies to treat cancer and other serious diseases. We have created a comprehensive, differentiated proprietary cell therapy platform focused on engineered macrophages and monocytes, cells that play a crucial role in both the innate and adaptive immune response. Carisma is headquartered in Philadelphia, PA. For more information, please visit www.carismatx.com.

Cautionary Note on Forward-Looking Statements

Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute "forward-looking statements" within the meaning of The Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements relating to Carisma's business, strategy, future operations, cash runway, the advancement of Carisma's product candidates and product pipeline, and clinical development of Carisma's product candidates, including expectations regarding timing of initiation and results of clinical trials. The words "anticipate," "believe," "contemplate," "continue," "could," "estimate," "expect," "goals," "intend," "may," "might," "outlook," "plan," "project," "potential," "predict," "target," "possible," "will," "would," "could," "should," and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words.

Any forward-looking statements are based on management's current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in, or implied by, such forward-looking statements. These risks and uncertainties include, but are not limited to, (i) Carisma's ability to realize the anticipated benefits of its pipeline reprioritization and corporate restructuring, (ii) Carisma's ability to obtain, maintain and protect its intellectual property rights related to its product candidates; (iii) Carisma's ability to advance the development of its product candidates under the timelines it anticipates in planned and future clinical trials and with its current financial and human resources; (iv) Carisma's ability to replicate in later clinical trials positive results found in preclinical studies and early-stage clinical trials of its product candidates; (v) Carisma's ability to realize the anticipated benefits of its research and development programs, strategic partnerships, research and licensing programs and academic and other collaborations; (vi) regulatory requirements or developments and Carisma's ability to obtain and maintain necessary approvals from the U.S. Food and Drug Administration and other regulatory authorities related to its product candidates; (vii) changes to clinical trial designs and regulatory pathways; (viii) risks associated with Carisma's ability to manage expenses; (ix) changes in capital resource requirements; (x) risks related to the inability of Carisma to obtain sufficient additional capital to continue to advance its product candidates and its preclinical programs; and (xi) legislative, regulatory, political and economic developments.

For a discussion of these risks and uncertainties, and other important factors, any of which could cause Carisma's actual results to differ from those contained in the forward-looking statements, see the "Risk Factors" set forth in the Company's Annual Report on Form 10-K for the year ended December 31, 2023, its Quarterly Report on Form 10-Q for the quarter ended June 30, 2024, as well as discussions of potential risks, uncertainties, and other important factors in Carisma's other recent filings with the Securities and Exchange Commission. Any forward-looking statements that are made in this press release speak as of the date of this press release. Carisma undertakes no obligation to revise the forward-looking statements or to update them to reflect events or circumstances occurring after the date of this press release, whether as a result of new information, future developments or otherwise, except as required by the federal securities laws.

Investors:
Shveta Dighe
Head of Investor Relations
investors@carismatx.com

Media Contact:
Julia Stern
(763) 350-5223
jstern@realchemistry.com

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/carisma-therapeutics-announces-upcoming-presentations-at-sitc-2024-302266909.html

SOURCE Carisma Therapeutics Inc.

FAQ

What presentations will Carisma Therapeutics (CARM) make at SITC 2024?

Carisma Therapeutics will present two posters at SITC 2024: one on pre-clinical efficacy of an anti-GPC3 CAR-M for hepatocellular carcinoma, and another on a Phase 1 study of autologous monocytes engineered to express an anti-HER2 CAR for HER2 overexpressing solid tumors.

When and where will Carisma Therapeutics (CARM) present at SITC 2024?

Carisma Therapeutics will present its posters on Friday, November 8, 2024, at the Exhibit Halls A B George R. Brown Convention Center in Houston, Texas, during the SITC 2024 conference taking place from November 6-10, 2024.

How can I access Carisma Therapeutics' (CARM) SITC 2024 poster presentations?

The posters presented at SITC 2024 will be available online in the 'Publications' section of Carisma's website at https://carismatx.com/technology/publications/ following the start of the poster session.

What are the publication numbers for Carisma Therapeutics' (CARM) SITC 2024 posters?

The publication numbers for Carisma Therapeutics' SITC 2024 posters are 329 for the anti-GPC3 CAR-M study and 659 for the Phase 1 study on autologous monocytes engineered to express an anti-HER2 CAR.

Carisma Therapeutics, Inc.

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