BioRestorative Therapies Receives Notice of Allowance for Patent Application in Israel for its Metabolic Program

Rhea-AI Summary

BioRestorative Therapies (OTC: BRTX) announced a significant milestone on September 23, 2021, as the Israeli Patent Office granted a Notice of Allowance for its ThermoStem program patent application. This patent will safeguard the use of implantable scaffolds that incorporate human brown adipose tissue stem cells, potentially treating various degenerative and metabolic disorders. CEO Lance Alstodt expressed satisfaction with the broader protection provided by this allowance compared to existing US patents, highlighting the technology's therapeutic relevance.

Positive

• Issuance of a Notice of Allowance for the ThermoStem patent in Israel signifies potential market expansion.
• Broader patent protection than existing US patents may enhance competitive positioning.

Negative

• None.

MELVILLE, N.Y., Sept. 23, 2021 (GLOBE NEWSWIRE) -- BioRestorative Therapies, Inc. (“BioRestorative” or the “Company”) (OTC: BRTX), a life sciences company focused on stem cell-based therapies, today announced that the Israeli Patent Office has issued BioRestorative a Notice of Allowance for a patent application for its metabolic ThermoStem^® program. 

Once issued in Israel, the patent will provide patent protection for implantable scaffolds combined with human brown adipose tissue stem cells, which can be implanted into patients. The technology is applicable for potential therapeutic uses for treating a wide range of degenerative and metabolic disorders.

“We are pleased to have received this allowance since issued claims in this application provide even broader protection than is found in our issued US patents,” said Lance Alstodt, CEO of BioRestorative Therapies.

About BioRestorative Therapies, Inc.

BioRestorative Therapies, Inc. (www.biorestorative.com) develops therapeutic products using cell and tissue protocols, primarily involving adult stem cells. Our two core programs, as described below, relate to the treatment of disc/spine disease and metabolic disorders:

• Disc/Spine Program (brtxDISC^™): Our lead cell therapy candidate, BRTX-100, is a product formulated from autologous (or a person’s own) cultured mesenchymal stem cells collected from the patient’s bone marrow. We intend that the product will be used for the non-surgical treatment of painful lumbosacral disc disorders or as a complementary therapeutic to a surgical procedure. The BRTX-100 production process utilizes proprietary technology and involves collecting a patient’s bone marrow, isolating and culturing stem cells from the bone marrow and cryopreserving the cells. In an outpatient procedure, BRTX-100 is to be injected by a physician into the patient’s damaged disc. The treatment is intended for patients whose pain has not been alleviated by non-invasive procedures and who potentially face the prospect of surgery. We have received authorization from the Food and Drug Administration to commence a Phase 2 clinical trial using BRTX-100 to treat chronic lower back pain arising from degenerative disc disease.

• Metabolic Program (ThermoStem^®): We are developing a cell-based therapy candidate to target obesity and metabolic disorders using brown adipose (fat) derived stem cells to generate brown adipose tissue (“BAT”). BAT is intended to mimic naturally occurring brown adipose depots that regulate metabolic homeostasis in humans. Initial preclinical research indicates that increased amounts of brown fat in animals may be responsible for additional caloric burning as well as reduced glucose and lipid levels. Researchers have found that people with higher levels of brown fat may have a reduced risk for obesity and diabetes.

Forward-Looking Statements

This press release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events or results to differ materially from those projected in the forward-looking statements as a result of various factors and other risks, including, without limitation, those set forth in the Company's latest Form 10-K filed with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and the Company undertakes no obligation to update such statements.

CONTACT:
Email: ir@biorestorative.com

FAQ

What is the significance of the Israeli Patent Office's Notice of Allowance for BioRestorative (BRTX)?

The Notice of Allowance for the ThermoStem patent signifies enhanced protection for BioRestorative's technology, potentially allowing for broader applications in treating metabolic disorders.

When was the Notice of Allowance issued for BioRestorative's ThermoStem patent?

The Notice of Allowance was issued on September 23, 2021.

How does the ThermoStem program benefit BioRestorative (BRTX)?

The ThermoStem program aims to provide therapies using brown adipose tissue stem cells, addressing conditions like obesity and metabolic disorders.

What does BioRestorative's CEO say about the new patent allowance?

CEO Lance Alstodt noted that the issued claims provide broader protection than existing US patents, which could enhance the company's market position.