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Blueprint Medicines Corp - BPMC STOCK NEWS

Welcome to our dedicated page for Blueprint Medicines news (Ticker: BPMC), a resource for investors and traders seeking the latest updates and insights on Blueprint Medicines stock.

Blueprint Medicines Corporation (Nasdaq: BPMC) is a leading biopharmaceutical company focused on developing highly selective and potent kinase therapies to treat genomically defined diseases. With a deep understanding of the genetic blueprint of cancer and other kinase-driven diseases, Blueprint Medicines leverages its proprietary chemical compounds to craft therapies for new and challenging targets.

Blueprint Medicines boasts a robust pipeline, spearheaded by AYVAKIT (avapritinib), a drug designed for the treatment of systemic mastocytosis (SM) and other related disorders. AYVAKIT has secured approvals in the U.S. and Europe, marking significant strides in offering therapeutic solutions for patients with advanced SM, indolent systemic mastocytosis (ISM), and highly specific mutations in gastrointestinal stromal tumors.

Among its promising pipeline, Blueprint Medicines is developing several innovative candidates, including BLU-808, aimed at treating mast cell disorders like chronic urticaria and sleep disruptions, and BLU-222, focusing on breast cancer treatment. The company consistently demonstrates its commitment to transforming patient care through groundbreaking research and development.

Recent achievements highlight the company's growth trajectory. In Q3 2023, Blueprint reported strong revenue growth following AYVAKIT's successful launch for ISM, supported by its favorable clinical profile. The European Medicines Agency has recently given a positive opinion for AYVAKYT, extending its indication to ISM patients, reflecting the company's continued expansion in global markets.

Blueprint Medicines remains dedicated to advancing its clinical pipeline, optimizing operational efficiency, and securing strategic partnerships to harness market potential. The company is committed to delivering innovative therapies, offering hope and improved outcomes for patients worldwide.

  • Core Business: Development of selective kinase therapies for genomically defined diseases.
  • Key Products: AYVAKIT/AYVAKYT for systemic mastocytosis and gastrointestinal stromal tumors.
  • Current Projects: Development of BLU-808, BLU-222, and other therapies targeting mast cell disorders and various cancers.
  • Recent Achievements: Strong revenue growth, positive EMA opinion, expansion in Europe.
  • Partnerships: Collaborations with global healthcare agencies and ongoing clinical trials.
Rhea-AI Summary

Blueprint Medicines reported strong Q2 2024 results, with AYVAKIT net product revenues of $114.1 million, representing over 185% year-over-year growth. The company raised its full-year 2024 AYVAKIT revenue guidance to $435-$450 million, up from $390-$410 million. Total revenues were $138.2 million for Q2 2024.

Key highlights include:

  • Initiated Phase 1 healthy volunteer trial of wild-type KIT inhibitor BLU-808
  • Presented positive combination safety data for CDK2 inhibitor BLU-222
  • Expects to initiate registration-enabling HARBOR Part 2 study of elenestinib in indolent systemic mastocytosis later this year

Blueprint Medicines reported a net loss of $50.0 million for Q2 2024, compared to $132.8 million in Q2 2023. The company's cash position as of June 30, 2024, was $868.5 million.

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Blueprint Medicines (NASDAQ: BPMC) has announced its plans to report second quarter 2024 financial results on Thursday, August 1, 2024. The company will host a live conference call and webcast at 8:00 a.m. ET to present the results and provide a corporate update. Interested parties can access the call by dialing 833-470-1428 (domestic) or 404-975-4839 (international) with the conference ID 299779. A webcast will also be available on the company's website under the Investors & Media section. The archived webcast will remain accessible for 30 days following the call.

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Blueprint Medicines (NASDAQ: BPMC) announced presentations at the EAACI and EHA annual meetings showcasing the durable clinical benefits of AYVAKIT® (avapritinib) for systemic mastocytosis (SM). Seven presentations, including four oral sessions, will highlight data across different studies like PIONEER, PATHFINDER, and PRISM. Key findings include sustained efficacy and safety of AYVAKIT, improved quality of life for patients, and significant overall response rates. The PRISM survey underscores the substantial impact of SM on patients' lives, emphasizing the urgency to diagnose and treat the condition. The presentations will be available on the company’s website.

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Blueprint Medicines announced updated Phase 1 data for their CDK2 inhibitor, BLU-222, in combination with ribociclib and fulvestrant, for HR+/HER2- breast cancer. The study showed BLU-222 was well-tolerated with no dose-limiting toxicities. Updated data indicate significant biomarker reductions correlated with BLU-222 exposure. Early results suggest clinical activity, including one unconfirmed partial response. Detailed findings will be presented at the 2024 ASCO Annual Meeting.

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Blueprint Medicines announced the granting of non-qualified stock options and restricted stock units to new employees under their 2020 Inducement Plan. The options have an exercise price of $94.86 per share and will vest over time based on continued employment.

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Blueprint Medicines reported strong first quarter 2024 results, generating $92.5 million in AYVAKIT net product revenues and raising full-year revenue guidance to $390-$410 million. The company is on track to submit an IND for BLU-808 in Q2 to strengthen its presence in allergy and inflammation. Blueprint Medicines continues to advance its pipeline, with key developments in mast cell disorders and HR+/HER2- breast cancer. Financially, the company anticipates growth in global product revenues, decreased operating expenses, and a strong cash position.

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Blueprint Medicines (NASDAQ: BPMC) will report its first quarter 2024 financial results on May 2, 2024, through a live conference call and webcast. Investors can access the call through dial-in or webcast to receive the corporate update.
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Blueprint Medicines (NASDAQ: BPMC) announced a webcast series featuring Dr. Mariana Castells, a mast cell expert, discussing the potential of mast cells in treating allergic and inflammatory diseases. The webcast will highlight Blueprint's research strategy and approach to modulating mast cells.
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Blueprint Medicines (Nasdaq: BPMC) granted non-qualified stock options and restricted stock units to three new employees under its 2020 Inducement Plan. The options have an exercise price of $96.42 per share, vesting over time based on continued employment. The RSUs also vest annually, subject to the employees' continued employment.
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Blueprint Medicines Corporation (Nasdaq: BPMC) granted stock options and restricted stock units to new employees under its 2020 Inducement Plan. The options have an exercise price of $95.12 per share, vesting over time, while the RSUs vest annually, subject to continued employment.
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FAQ

What is the current stock price of Blueprint Medicines (BPMC)?

The current stock price of Blueprint Medicines (BPMC) is $96.57 as of February 28, 2025.

What is the market cap of Blueprint Medicines (BPMC)?

The market cap of Blueprint Medicines (BPMC) is approximately 5.7B.

What is Blueprint Medicines Corporation's primary focus?

Blueprint Medicines Corporation focuses on developing highly selective and potent kinase therapies for the treatment of genomically defined diseases.

What is AYVAKIT?

AYVAKIT (avapritinib) is a kinase inhibitor approved for the treatment of various forms of systemic mastocytosis (SM) and specific mutations in gastrointestinal stromal tumors.

What recent achievements has Blueprint Medicines made?

Recent achievements include strong revenue growth following AYVAKIT’s launch for indolent systemic mastocytosis (ISM) and a positive opinion from the European Medicines Agency for expanding AYVAKYT’s indications.

What are some key products in Blueprint Medicines' pipeline?

Key products in the pipeline include BLU-808 for mast cell disorders and BLU-222 for breast cancer treatment.

What sets Blueprint Medicines apart in drug development?

Blueprint Medicines stands out for its deep understanding of genetic drivers of disease and its proprietary library of novel chemical compounds, enabling the creation of kinase therapies targeting difficult-to-drug genomic subsets.

How does Blueprint Medicines contribute to patient care?

By focusing on genomically defined subsets of patients, Blueprint Medicines aims to create more efficient clinical development paths, improving the likelihood of successful outcomes and better patient care.

Where can I learn more about Blueprint Medicines’ clinical trials?

Information about ongoing or planned clinical trials can be found at blueprintclinicaltrials.com or clinicaltrials.gov.

How can I contact Blueprint Medicines for more information?

For more information, visit their website at www.BlueprintMedicines.com, or follow them on Twitter (@BlueprintMeds) and LinkedIn.

What are the company’s future plans for AYVAKIT?

Blueprint Medicines plans to continue expanding AYVAKIT's indications and market reach, particularly in Europe and the U.S., driven by its strong clinical profile and patient demand.

What are the primary therapeutic areas Blueprint Medicines is focusing on?

Blueprint Medicines is focusing on allergy/inflammation and oncology/hematology, with a strategic investment in therapeutic areas leveraging their core expertise and business infrastructure.
Blueprint Medicines Corp

Nasdaq:BPMC

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BPMC Stock Data

5.66B
63.00M
1.27%
104.9%
8.09%
Biotechnology
Pharmaceutical Preparations
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United States
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