Blueprint Medicines Corporation - BPMC STOCK NEWS

Blueprint Medicines Corporation (NASDAQ: BPMC) will host a live conference call on February 17, 2021, at 8:30 a.m. ET to discuss its fourth quarter and full year 2020 financial results along with corporate updates. Interested parties can access the call by dialing (855) 728-4793 for domestic calls or (503) 343-6666 for international calls, using conference ID 4844138. The event will also be available via a webcast on their Investors & Media section of their website. An archived version of the call will be accessible for 30 days following the event.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced the grant of non-qualified stock options and restricted stock units (RSUs) to eight new employees, totaling 15,226 shares of common stock and 7,613 RSUs, effective February 1, 2021. These grants are part of the 2020 Inducement Plan aimed at attracting new talent. The options have an exercise price of $98.57 per share, aligning with the stock's closing price on the grant date. Vesting for options and RSUs will occur over four years, contingent on continued employment.

Blueprint Medicines Corporation (NASDAQ: BPMC) has announced leadership changes in its R&D organization effective January 11, 2021. Dr. Becker Hewes succeeds Dr. Andy Boral as Chief Medical Officer, while Dr. Boral transitions to Executive Vice President, Clinical Development. Dr. Hewes has 20 years of experience in oncology and will oversee various clinical aspects. Additionally, Dr. Marion Dorsch will resign as Chief Scientific Officer effective March 1, 2021. The company looks to enhance its focus on precision medicine and expand its R&D capabilities.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced key milestones and goals for 2021. The company achieved four regulatory approvals in 2020, including breakthrough therapy designation for AYVAKIT for systemic mastocytosis. They aim to accelerate the global adoption of AYVAKIT and GAVRETO while advancing new therapies including BLU-263 and candidates for EGFR-driven non-small cell lung cancer. The company expects to maintain a self-sustaining financial profile, bolstered by existing cash and anticipated product revenues.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced on January 5, 2021, that its Compensation Committee granted non-qualified stock options for 7,675 shares and 3,837 restricted stock units (RSUs) to three new employees, effective January 1, 2021. This is part of the 2020 Inducement Plan, designed to attract new talent. The options have an exercise price of $112.15 per share, the closing price on December 31, 2020, and will vest over four years, while the RSUs will vest over four annual increments. These actions reflect the company's strategy to enhance its workforce.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced the submission of a supplemental new drug application (sNDA) for AYVAKIT™ (avapritinib) to the FDA, targeting adult patients with advanced systemic mastocytosis (SM). The application seeks priority review, potentially resulting in a six-month evaluation period. AYVAKIT is designed to inhibit D816V mutant KIT, the primary driver of systemic mastocytosis. The clinical data show promising response rates and overall survival benefits for patients. Blueprint Medicines aims to be the first to offer a precision therapy addressing this rare disease.

Blueprint Medicines Corporation (NASDAQ: BPMC) recently presented significant data at the 62nd American Society of Hematology Annual Meeting, focusing on systemic mastocytosis (SM). Their investigational therapy, AYVAKIT, is notable for achieving a 75% overall response rate and a 36% complete remission rate in advanced SM patients. The company plans to submit a supplemental new drug application to the FDA for AYVAKIT this month. Additionally, new diagnostic tools highlighted the urgent need for improved SM diagnosis, underscoring the severe impact of this rare disease on patient quality of life.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced the granting of non-qualified stock options for 16,354 shares and 8,174 restricted stock units (RSUs) to eight new employees, effective December 1, 2020. This grant is part of the 2020 Inducement Plan, adhering to NASDAQ Listing Rule 5635(c)(4). The stock options have an exercise price of $105.65 per share, matching the closing price on the grant date. Vesting schedules for both options and RSUs are detailed, ensuring employee retention as they vest based on continued employment.

Blueprint Medicines Corporation (NASDAQ: BPMC) has received FDA approval for GAVRETO™ (pralsetinib), a targeted therapy for patients with RET-altered thyroid cancers. This accelerated approval includes adult and pediatric patients with advanced RET-mutant medullary thyroid cancer and RET fusion-positive thyroid cancer. GAVRETO is a once-daily oral therapy designed to selectively target RET alterations in various tumors. The approval is based on efficacy data from the Phase 1/2 ARROW trial, which showed a 60% overall response rate in RET-mutant MTC patients.