Blueprint Medicines Corporation - BPMC STOCK NEWS

Blueprint Medicines Corporation (NASDAQ: BPMC) announced a positive opinion from the European Medicines Agency's CHMP to expand the indication for AYVAKYT® (avapritinib) for adults with advanced systemic mastocytosis (ASM), SM-AHN, or mast cell leukemia after prior therapy. This decision, based on Phase 1 and Phase 2 trial results, could provide new treatment options for approximately 40,000 patients in Europe with this rare disease. A final decision by the European Commission is expected by early April 2022.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced key executive changes effective April 4, 2022. Philina Lee, Ph.D., will become Chief Commercial Officer, taking over from Christina Rossi, who will transition to Chief Operating Officer. Helen Ho, Ph.D., will expand her role to Chief Business Officer, overseeing Portfolio Strategy & Program Management. CEO Jeff Albers emphasized the importance of cultivating internal talent and succession planning for the company’s growth in the next 12-18 months. Lee has been pivotal in the launch of AYVAKIT® and GAVRETO®, while Ho has strengthened strategic partnerships.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced key goals for 2022, aiming to solidify its leadership in precision therapy. The company plans to expand treatment options for systemic mastocytosis, with regulatory submissions and new clinical trial data expected throughout the year. Financially, Blueprint Medicines reported approximately $52.9 million in global product revenues for AYVAKIT in 2021, marking a 150% increase. With over $1.0 billion in cash as of year-end 2021, the company is well-positioned for growth and aims for self-sustainable financial health.

Blueprint Medicines Corporation announced the granting of non-qualified stock options for 9,725 shares and 4,862 restricted stock units (RSUs) to seven new employees as part of its 2020 Inducement Plan, effective January 1, 2022. The exercise price for these options is set at $107.11 per share, matching the closing stock price from December 31, 2021. The RSUs will vest over four years, while the options will vest 25% after one year and monthly thereafter, contingent upon continued employment. This strategy aims to attract new talent to advance the company's precision therapies for cancer and rare diseases.

Blueprint Medicines Corporation (NASDAQ: BPMC) has announced the appointment of Kate Haviland as the new CEO, effective April 4, 2022, succeeding Jeff Albers, who will transition to Executive Chairman. The Board emphasized that this leadership change is a result of a long-term succession planning process aimed at ensuring continuity and strategic growth. Additionally, Christina Rossi has been promoted to COO, expanding her role in corporate affairs and portfolio strategy. Haviland has been with the company since 2016 and brings extensive experience in oncology and rare diseases.

Blueprint Medicines Corporation (NASDAQ: BPMC) has completed its acquisition of Lengo Therapeutics for $250 million in cash, with potential additional payments of $215 million based on regulatory and sales milestones. This acquisition includes LNG-451, an oral precision therapy aimed at treating non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion mutations. The IND application for LNG-451 was submitted to the FDA in December 2021, with plans to advance into clinical trials in early 2022.

Blueprint Medicines Corporation (NASDAQ: BPMC) has appointed Daniella Beckman to its board of directors. With over 20 years of experience in corporate strategy and finance within the biopharmaceutical sector, Beckman aims to bolster the company’s strategic direction. CEO Jeff Albers highlighted her expertise as a valuable addition as the company seeks growth in precision therapies. Beckman's prior finance roles include positions at Tango Therapeutics and Idenix Pharmaceuticals, enhancing her capability to guide BPMC's future endeavors.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced the granting of stock options and restricted stock units (RSUs) to thirteen new employees under its 2020 Inducement Plan, effective December 1, 2021. The grants included 39,862 stock options with an exercise price of $96.03 per share and 19,930 RSUs. These awards are to incentivize new hires as outlined by NASDAQ Listing Rule 5635(c)(4). The options will vest over four years, while the RSUs will vest over four years as well, contingent upon continued employment.

Blueprint Medicines Corporation (NASDAQ: BPMC) announced two significant Nature Medicine publications on the EXPLORER and PATHFINDER trials for AYVAKIT® (avapritinib), demonstrating its effectiveness in treating advanced systemic mastocytosis (SM). The studies included approximately 150 patients, showing a 75% overall response rate in both trials. AYVAKIT received FDA approval in June 2021. The data highlights improvements in patient symptoms and survival benefits, supporting Blueprint's commitment to advancing treatment for patients with this rare disorder.