Burning Rock to Present Data on Its Early Detection ELSA-seq at ESMO Asia Virtual Congress 2020
Burning Rock Biotech Limited (NASDAQ: BNR) announced that new data for its ELSA-seq test will be presented at the ESMO Asia Virtual Congress on November 20. The ELSA-seq test focuses on early cancer detection through targeted methylation sequencing, which analyzes epigenetic changes in cell-free DNA. The THUNDER pilot study aims to develop and validate this test, showcasing results from the THUNDER-II substudy, which covers various cancers including those in the lung and pancreas. Burning Rock's mission is to enhance precision oncology using advanced sequencing technologies.
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GUANGZHOU, China, Oct. 20, 2020 (GLOBE NEWSWIRE) -- Burning Rock Biotech Limited (NASDAQ: BNR, the “Company” or “Burning Rock”) today announced that new data for its early detection ELSA-seq test will be presented at the upcoming European Society for Medical Oncology (ESMO) Asia Virtual Congress, on Friday, November 20.
Early cancer detection can potentially offer clinical benefits, particularly for those without effective screening methods. As a pilot project, the THUNDER (the unintrusive detection of early-stage cancers) study has been designed for the development and validation of ELSA-seq, a blood-based targeted methylation sequencing test. By interrogating the epigenetic alterations from circulating cell-free DNA (cfDNA), ELSA-seq enabled sensitive detection and accurate localization of early-stage tumors (THUNDER-I), previously reported by a poster titled “Multiplatform analysis of early-stage cancer signatures in blood” at the American Association for Cancer Research (AACR) Special Conference on Advances in Liquid Biopsies in January 2020. Poster link here.
The mini oral presentation “Early detection and localization of multiple cancers using a blood-based methylation assay (ELSA-seq)” (abstract number 602/LBA3) will report results of the training and validation sets from the second THUNDER substudy (THUNDER-II), on malignancies developed in lung, liver, colon/rectum, esophagus, pancreas, and ovary.
About Burning Rock
Burning Rock Biotech Limited (NASDAQ: BNR), whose mission is to guard life via science, focuses on the application of next generation sequencing (NGS) technology in the field of precision oncology. Its business consists of i) NGS-based therapy selection testing for late-stage cancer patients, with the leading market share in China and over 185,000 tissue and liquid-based tests completed cumulatively, and ii) cancer early detection, which has moved beyond proof-of-concept R&D into the clinical validation stage.
For more information about Burning Rock, please visit: www.brbiotech.com.
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