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Burning Rock to Present Data on Its Early Detection ELSA-seq at ESMO Asia Virtual Congress 2020

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Burning Rock Biotech Limited (NASDAQ: BNR) announced that new data for its ELSA-seq test will be presented at the ESMO Asia Virtual Congress on November 20. The ELSA-seq test focuses on early cancer detection through targeted methylation sequencing, which analyzes epigenetic changes in cell-free DNA. The THUNDER pilot study aims to develop and validate this test, showcasing results from the THUNDER-II substudy, which covers various cancers including those in the lung and pancreas. Burning Rock's mission is to enhance precision oncology using advanced sequencing technologies.

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GUANGZHOU, China, Oct. 20, 2020 (GLOBE NEWSWIRE) -- Burning Rock Biotech Limited (NASDAQ: BNR, the “Company” or “Burning Rock”) today announced that new data for its early detection ELSA-seq test will be presented at the upcoming European Society for Medical Oncology (ESMO) Asia Virtual Congress, on Friday, November 20.

Early cancer detection can potentially offer clinical benefits, particularly for those without effective screening methods. As a pilot project, the THUNDER (the unintrusive detection of early-stage cancers) study has been designed for the development and validation of ELSA-seq, a blood-based targeted methylation sequencing test. By interrogating the epigenetic alterations from circulating cell-free DNA (cfDNA), ELSA-seq enabled sensitive detection and accurate localization of early-stage tumors (THUNDER-I), previously reported by a poster titled “Multiplatform analysis of early-stage cancer signatures in blood” at the American Association for Cancer Research (AACR) Special Conference on Advances in Liquid Biopsies in January 2020. Poster link here.

The mini oral presentation “Early detection and localization of multiple cancers using a blood-based methylation assay (ELSA-seq)” (abstract number 602/LBA3) will report results of the training and validation sets from the second THUNDER substudy (THUNDER-II), on malignancies developed in lung, liver, colon/rectum, esophagus, pancreas, and ovary.

About Burning Rock

Burning Rock Biotech Limited (NASDAQ: BNR), whose mission is to guard life via science, focuses on the application of next generation sequencing (NGS) technology in the field of precision oncology. Its business consists of i) NGS-based therapy selection testing for late-stage cancer patients, with the leading market share in China and over 185,000 tissue and liquid-based tests completed cumulatively, and ii) cancer early detection, which has moved beyond proof-of-concept R&D into the clinical validation stage.

For more information about Burning Rock, please visit: www.brbiotech.com.

Safe Harbor Statement

This press release contains forward-looking statements. These statements constitute “forward-looking” statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and as defined in the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will,” “expects,” “anticipates,” “future,” “intends,” “plans,” “believes,” “estimates,” “target,” “confident” and similar statements. Burning Rock may also make written or oral forward-looking statements in its periodic reports to the SEC, in its annual report to shareholders, in press releases and other written materials and in oral statements made by its officers, directors or employees to third parties. Statements that are not historical facts, including statements about Burning Rock’s beliefs and expectations, are forward-looking statements. Such statements are based upon management’s current expectations and current market and operating conditions, and relate to events that involve known or unknown risks, uncertainties and other factors, all of which are difficult to predict and many of which are beyond Burning Rock’s control. Forward-looking statements involve risks, uncertainties and other factors that could cause actual results to differ materially from those contained in any such statements. All information provided in this press release is as of the date of this press release, and Burning Rock does not undertake any obligation to update any forward-looking statement as a result of new information, future events or otherwise, except as required under applicable law.

FAQ

What is the ELSA-seq test announced by Burning Rock Biotech?

The ELSA-seq test is a blood-based targeted methylation sequencing test for early cancer detection.

When will Burning Rock present its ELSA-seq data?

Burning Rock will present its ELSA-seq data at the ESMO Asia Virtual Congress on November 20.

What types of cancers does the THUNDER-II substudy focus on?

The THUNDER-II substudy focuses on malignancies in lung, liver, colon/rectum, esophagus, pancreas, and ovary.

What is the aim of the THUNDER study by Burning Rock?

The THUNDER study aims to develop and validate the ELSA-seq test for early-stage cancer detection.

What is Burning Rock Biotech's focus in oncology?

Burning Rock Biotech focuses on precision oncology, utilizing next-generation sequencing technology for therapy selection and early cancer detection.

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