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Bionomics Limited American Depository Shares (symbol: BNOX) is a global clinical-stage biopharmaceutical company dedicated to developing novel treatments for serious diseases. The company's primary focus lies in treating central nervous system (CNS) disorders such as anxiety, depression, and Alzheimer's disease, as well as various forms of cancer.
Bionomics boasts a highly productive drug discovery platform, including its proprietary Multicore® chemistry capability, which fuels its diverse pipeline of drug candidates. The company's portfolio ranges from early-stage to advanced clinical development programs, positioning Bionomics as a leader in innovative drug discovery.
A key strength of Bionomics is its strategic partnerships with large pharmaceutical companies. These collaborations enable Bionomics to expedite the development and market introduction of its drug candidates, allowing the company to concentrate on its core strength of innovative research and discovery.
Among its recent achievements, Bionomics is progressing its Phase 2b trial of BNC210, a promising treatment for Post-Traumatic Stress Disorder (PTSD). The trial aims to evaluate the safety and efficacy of 900 mg BNC210 administered twice daily as monotherapy for PTSD. The trial involves 212 participants across 27 sites in the United States and 7 sites in the United Kingdom.
Financially, Bionomics generates all of its revenue from Australia, with a robust growth phase backed by substantial research and development investments. The company is committed to providing better treatment options for diseases with unmet medical needs, driven by a team of experts dedicated to making a difference in patients' lives.
For the latest updates and detailed information about Bionomics Limited, please visit their official website at www.bionomics.com.au.
Bionomics (BNOX) has received approval from the Supreme Court of New South Wales for its re-domiciliation from Australia to the United States. Under the approved scheme, Neuphoria Therapeutics, a Delaware , will become Bionomics' ultimate parent company. The scheme became legally effective upon court order lodgment with Australian Securities & Investments Commission.
Bionomics' ADSs will continue trading on Nasdaq until the implementation date of December 23, 2024. Shareholders holding shares as of 5:00pm Sydney time on December 17, 2024 will receive scheme consideration. Neuphoria shares are expected to begin trading on Nasdaq under the symbol NEUP on December 24, 2024 or shortly thereafter.
Bionomics (BNOX) shareholders have approved the company's proposed re-domiciliation from Australia to the United States through a Scheme of Arrangement. Under this scheme, Neuphoria Therapeutics Inc., a Delaware , will become Bionomics' ultimate parent company. The shareholder vote showed strong support with 96% of votes cast in favor and 87% of shareholders present voting in favor.
The implementation remains subject to several conditions, including approval from the Supreme Court of New South Wales and maintenance of the independent expert's favorable conclusion. If all conditions are met, the implementation is expected around December 24, 2024, with Neuphoria shares beginning trading on Nasdaq under the symbol NEUP on or shortly after that date.
Bionomics (NASDAQ: BNOX) has published positive Phase 2 ATTUNE study results for BNC210 in PTSD patients in NEJM Evidence. The study showed significant improvements in PTSD symptom severity at Week 12, with efficacy observed as early as Week 4. Key findings include improvements in the Clinician-Administered PTSD Scale (CAPS-5) scores, depressive symptoms, and sleep quality.
BNC210, positioned as a non-psychedelic, non-sedating, and non-habit-forming treatment, demonstrated a manageable safety profile. Common adverse events included headache, nausea, fatigue, and hepatic enzyme elevations, occurring in 66.7% of BNC210 patients versus 53.8% in the placebo group. The company plans to initiate a Phase 3 study in H2 2025 and is currently conducting a Phase 3 AFIRM-1 study in social anxiety disorder with results expected in Q3 2025.
Bionomics (BNOX) has announced its upcoming presentation at the 63rd Annual Meeting of the American College of Neuropsychopharmacology (ACNP) in Phoenix, AZ, from December 8-11, 2024. The company will present results from their Phase 2 ATTUNE trial of BNC210 in post-traumatic stress disorder during the inaugural 'Promising Targets' session.
The presentation, titled 'Randomized, Double-Blind Study of BNC210, a Negative Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor, in Posttraumatic Stress Disorder (PTSD): The Attune Trial,' will be delivered by Murray Stein, M.D., M.P.H. on December 8, 2024, at 3:00 pm. The presentation slides will be made available on the company's website under the Publications webpage after the meeting.
Bionomics (Nasdaq: BNOX) is urging shareholders to vote on their proposed re-domiciliation from Australia to the United States. The company's Board of Directors and an independent expert have unanimously determined that the re-domiciliation through the Scheme Implementation Agreement is in shareholders' best interests.
The voting deadlines are December 3, 2024, 10:00 am New York time for American Depositary Shares holders and December 10, 2024, 8:30 am Sydney time for ordinary shares holders. The Scheme Meeting will be held virtually on December 12, 2024, at 8:30 am Sydney time (December 11, 2024, 4:30 pm New York time).
Bionomics (BNOX) announced updates to its proposed re-domiciliation to the United States through a scheme of arrangement. Shareholders will receive shares in Neuphoria Therapeutics, a Delaware-incorporated company, at a revised exchange ratio: one Neuphoria common stock for every 2,160 Bionomics ordinary shares, or one for every 12 ADSs. Small Parcel Holders (fewer than 200,000 shares) can opt into a Sale Facility. The Scheme Meeting is scheduled for December 12, 2024, with the Scheme Booklet distribution expected around November 13, 2024. The Bionomics Board unanimously recommends shareholders vote in favor of the scheme.
Bionomics (BNOX), a clinical-stage biotech company focused on developing first-in-class allosteric ion channel modulators for CNS disorders, has announced its participation in the 15th CNS Summit. The event will take place from November 10-13, 2024, at the Encore Boston Hotel in Boston, MA.
Dr. Spyros Papapetropoulos, President and CEO, will deliver a company presentation during the Neuroscience Spotlight session on Tuesday, November 12 at 1:00 p.m. ET in the Picasso ballroom. The presentation will subsequently be available on Bionomics' website under the Events page in the Investors Center section.
Bionomics (Nasdaq: BNOX) has received a AUS$1M milestone payment from Carina Biotech for their partnered legacy oncology program BNC101. The payment is part of an exclusive worldwide license agreement signed in November 2020 for BNC101, a monoclonal antibody targeting LGR5. Under the agreement, Bionomics could receive up to AUS$118 million in development, regulatory, and commercial milestone payments. Additionally, Bionomics is entitled to royalties ranging from low to mid-single digits on net sales, plus a percentage of sublicensing revenues. The company also highlighted its partnership with Merck for CNS conditions, valued at ~US$500M.
Bionomics (BNOX), a clinical-stage biotech company focused on developing allosteric ion channel modulators for CNS disorders, announces its participation in the ThinkEquity Conference on October 30, 2024. The event will be held at the Mandarin Oriental Hotel in New York. Dr. Spyros Papapetropoulos, President and CEO, will present at 1:30 p.m. ET in the Lotus Suite West. The presentation will be available via live webcast, and management will conduct one-on-one meetings with investors. A replay will be accessible on the company's website under the Events page.
Bionomics (Nasdaq: BNOX), a clinical-stage biotechnology company focused on developing novel allosteric ion channel modulators for serious central nervous system (CNS) disorders, has been invited to present at the 2024 Maxim Healthcare Virtual Summit. The event, presented by Maxim Group , begins on October 15th, 2024, at 9:00 a.m. ET.
Dr. Spyros Papapetropoulos, President and CEO of Bionomics, will participate in a fireside chat with Maxim's Senior Analysts on October 16th at 10:30 a.m. ET. Interested parties can attend by signing up for M-Vest membership. This presentation provides an opportunity for Bionomics to showcase its progress in developing treatments for CNS disorders with high unmet medical needs.
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