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Bionano Genomics, Inc. (Nasdaq: BNGO) is a pioneering company in the life sciences instrumentation sector, dedicated to advancing genome biology understanding through innovative solutions. The company is renowned for its development and marketing of the Saphyr™ system, an ultra-sensitive platform designed for structural variation detection. This system enables researchers and clinicians to accelerate diagnostics and therapeutic target discovery, streamlining studies on chromosomal changes.
Bionano's core mission is to transform genomic analysis through optical genome mapping (OGM) solutions, diagnostic services, and software. Their flagship product, Saphyr™, offers unmatched capabilities in structural variation discovery and the ability to construct comprehensive genome assemblies. This technology is crucial for applications in cancer research, human disease studies, agricultural bioengineering, and genome discovery.
Recent achievements include the detection of unique structural variations and gene fusions in blood cancer samples, underscoring OGM's potential as a complement to traditional sequencing methods. Bionano's OGM technology has shown superior sensitivity and resolution in various studies, highlighting its utility in pediatric leukemia and other cancers.
The company operates globally with significant revenue from the Americas, and it generates product revenue from the sales of OGM and Ionic Purification systems and consumables. Bionano also offers diagnostic testing for neurodevelopmental disabilities through its Lineagen, Inc. d/b/a Bionano Laboratories business and industry-leading genome analysis software that integrates next-generation sequencing and microarray data.
Partnerships with AI-driven companies like Diagens further enhance Bionano's offerings, aiming to improve reproductive health and other clinical applications. Additionally, Bionano continuously upgrades its VIA software and Bionano Solve pipeline to provide researchers with precise and sensitive genomic research tools.
For more information, visit Bionano Genomics and its associated websites, www.bionanolaboratories.com and www.purigenbio.com.
Bionano Genomics (BNGO) will host a conference call and webcast on March 23, 2021, at 4:30 p.m. Eastern Time to discuss its fourth quarter and year-end financial results for 2020. The company will also highlight recent corporate advancements. Participants can join the call by dialing the provided toll-free or international numbers. Bionano provides genome analysis tools via its Saphyr system, aimed at enhancing genetic research and diagnostics.
Bionano Genomics (BNGO) announced that Praxis Genomics received DEX Z-codes from Palmetto MolDX for its complete menu of laboratory developed tests (LDTs) based on the Saphyr system. These codes enhance clarity for payers regarding molecular diagnostics tests and could accelerate claim payments. Praxis is the first CAP-accredited lab in the U.S. to offer LDTs based on whole genome analysis with Saphyr, potentially leading to Medicare and private insurance reimbursement for optical genome mapping (OGM) tests. Bionano aims to improve the Saphyr system's throughput to 17,000 samples annually by mid-2023.
Bionano Genomics (Nasdaq: BNGO) announced that its CEO, Erik Holmlin, will present virtually at the Cowen 41st Annual Health Care Conference on March 4, 2021, at 2:10 PM EST. The presentation will be accessible via a live webcast on Bionano's Investors section and will be archived for 30 days post-event. Bionano specializes in genome analysis tools, particularly through its Saphyr system, which aids in structural variation detection for genetic research.
Bionano Genomics (BNGO) announced its participation in the 2021 Advances in Genome Biology and Technology (AGBT) meeting, showcasing its Saphyr System for optical genome mapping. The virtual conference, held from March 1-3, will feature presentations from leading institutions, including Boston Children’s Hospital and Harvard Medical School, focusing on psychiatric disorders and cancer.
Key activities include a plenary talk on pediatric psychiatric disorders and various poster presentations. Bionano's CEO and CMO will also participate in a live interview during the conference.
Bionano Genomics announced a significant contribution of its optical genome mapping (OGM) technology to a study published in Science, unveiling thousands of large structural variant calls not captured by traditional methods. The study showcased 64 haplotype-resolved genomes, enhancing understanding of human genetic diversity. OGM identified 5,590 large structural variants, crucial for understanding genetic disorders. This advancement underscores OGM's role in genome analysis, urging researchers to integrate structural data for deeper insights into genetic variation.
Bionano Genomics announced the publication of a study from its Lineagen team that introduces a groundbreaking scoring algorithm called NeuroSCORE. This model evaluates nearly all protein-coding genes for their potential to cause central nervous system (CNS) disorders. By integrating this with the Saphyr platform, the company enhances its diagnostic capabilities. NeuroSCORE combines data from multiple databases, allowing for better identification of variants of unknown significance (VUS) and potentially discovering novel genes linked to conditions like autism spectrum disorder.
Bionano Genomics (Nasdaq: BNGO) will present at the BTIG MedTech, Digital Health, Life Science & Diagnostic Tools Conference on February 18, 2021, at 1:30 PM PST. CEO Erik Holmlin will participate in a fireside chat. A live webcast can be accessed on Bionano’s Investors website and will be archived for 30 days. Bionano specializes in genome analysis and diagnostic testing through its Saphyr system and Lineagen business, focusing on autism spectrum disorder and other neurodevelopmental disabilities.
Bionano Genomics has announced a significant study showcasing the effectiveness of its Saphyr system for analyzing solid tumors. Conducted by Dr. James Broach, the research demonstrated that Saphyr can detect structural variants (SVs) in various cancer types, including breast and lung cancers. The findings reveal the system's ability to isolate high-quality DNA and identify important cancer gene variants, potentially facilitating targeted therapies. This development opens new avenues for cancer diagnostics and treatment, enhancing Saphyr's role in oncology.
Bionano Genomics (Nasdaq: BNGO) has initiated a pilot program for its Saphyr system at the University Health Network's Laboratory Medicine Program in Toronto, Canada's largest hospital diagnostic lab. This program aims to enhance cancer diagnostics by employing optical genome mapping (OGM) to improve the detection of chromosomal abnormalities and reduce costs. With UHN performing 25 million tests annually, this collaboration represents a significant step forward in streamlining cytogenomic analysis and potentially transforming cancer diagnosis.
Bionano Genomics (Nasdaq: BNGO) announced the availability of presentation recordings from its recent Next-Generation Cytogenomics Symposium, held from January 11 to 15, where over 15,500 registrations were recorded. The event, featuring 33 presentations by Saphyr users, focused on optical genome mapping applications, including studies on genetic diseases and COVID-19. CEO Erik Holmlin highlighted the symposium's role in enhancing awareness of the Saphyr system, which aims to improve diagnostics and therapeutic targets. The recordings are accessible on Bionano's website and YouTube page.
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