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Bionano Genomics, Inc. (Nasdaq: BNGO) is a pioneering company in the life sciences instrumentation sector, dedicated to advancing genome biology understanding through innovative solutions. The company is renowned for its development and marketing of the Saphyr™ system, an ultra-sensitive platform designed for structural variation detection. This system enables researchers and clinicians to accelerate diagnostics and therapeutic target discovery, streamlining studies on chromosomal changes.
Bionano's core mission is to transform genomic analysis through optical genome mapping (OGM) solutions, diagnostic services, and software. Their flagship product, Saphyr™, offers unmatched capabilities in structural variation discovery and the ability to construct comprehensive genome assemblies. This technology is crucial for applications in cancer research, human disease studies, agricultural bioengineering, and genome discovery.
Recent achievements include the detection of unique structural variations and gene fusions in blood cancer samples, underscoring OGM's potential as a complement to traditional sequencing methods. Bionano's OGM technology has shown superior sensitivity and resolution in various studies, highlighting its utility in pediatric leukemia and other cancers.
The company operates globally with significant revenue from the Americas, and it generates product revenue from the sales of OGM and Ionic Purification systems and consumables. Bionano also offers diagnostic testing for neurodevelopmental disabilities through its Lineagen, Inc. d/b/a Bionano Laboratories business and industry-leading genome analysis software that integrates next-generation sequencing and microarray data.
Partnerships with AI-driven companies like Diagens further enhance Bionano's offerings, aiming to improve reproductive health and other clinical applications. Additionally, Bionano continuously upgrades its VIA software and Bionano Solve pipeline to provide researchers with precise and sensitive genomic research tools.
For more information, visit Bionano Genomics and its associated websites, www.bionanolaboratories.com and www.purigenbio.com.
Bionano Genomics (BNGO) has announced a conference call and live webcast to discuss its Q1 2022 financial results on May 5, 2022, at 4:30 p.m. ET. This event aims to highlight the company's recent corporate progress in genome analysis solutions, which support researchers and clinicians in biology and medicine. Bionano's offerings include Optical Genome Mapping (OGM) solutions, diagnostic testing through Lineagen, and BioDiscovery software for genomic data analysis.
TwinStrand Biosciences has appointed Goran Pljevaljcic, Ph.D., as Chief Commercial Officer. He brings over 20 years of experience in the genomics industry, including significant roles at Bionano Genomics (NASDAQ: BNGO). This leadership change aims to strengthen the company's commercial strategy as it expands its high-resolution duplex sequencing offerings, which enhance the detection of low-frequency genomic variants. Dr. Pljevaljcic's expertise is expected to accelerate the deployment of these technologies for clinical applications, improving healthcare outcomes.
Bionano Genomics, Inc. (Nasdaq: BNGO) recently announced the issuance of two new US patents, No. 11,291,999 and No. 11,292,713, by the United States Patent and Trademark Office on April 5, 2022. The ‘999 patent focuses on a novel apparatus for minimizing biopolymer aggregation in nanochannels, enhancing DNA loading cycles. The ‘713 patent expands patent protection for optical genome mapping technology, detailing methods for detecting genomic variants. These patents bolster Bionano's intellectual property portfolio, supporting its goal of advancing genomic insights in clinical research.
Bionano Genomics, Inc. (BNGO), has launched a new integrated genomic scar analysis feature for homologous recombination deficiency (HRD) in its N×Clinical 6.2 software release. This capability allows for a comprehensive, automated analysis of tumor biomarkers from next-generation sequencing and microarray data. It aims to improve therapeutic response stratification across various tumor types. The software can measure genomic instability through three genomic scars, enhancing HRD assessment and supporting clinical trials. Bionano is also collaborating with Friends of Cancer Research on HRD biomarker research.
Bionano Genomics (BNGO) announced a new study showcasing the effectiveness of its optical genome mapping (OGM) technology in characterizing genomic variations in B-cell acute lymphoblastic leukemia (B-ALL). Conducted by University Hospitals Leuven, the study involved 12 subjects and utilized various methods, including OGM and single-cell analysis, to identify genetic variations associated with B-ALL. CEO Erik Holmlin emphasized the growing applications of OGM in cancer research and its potential to complement traditional cytogenetic methods. This advancement underscores OGM's viability as a tool in targeted therapy selection.
Bionano Genomics (BNGO) announces participation in the American Association for Cancer Research (AACR) Annual Meeting from April 8-13, 2022, in New Orleans. The company will showcase its optical genome mapping (OGM) solutions, NxClinical software, and laboratory services. Notable presentations include research on genomic structural variations and homologous recombination deficiency (HRD) analysis. Bionano will also introduce NxClinical version 6.2, enhancing HRD analysis capabilities. This participation aims to demonstrate the potential impact of their solutions in cancer research.
Bionano Genomics (BNGO) announced the 2022 China Symposium, scheduled for March 26, featuring 9 presentations from leading Chinese researchers on optical genome mapping (OGM) applications. Topics include human fertility, prenatal genetics, hematological disorders, and solid tumors. Key speakers include Bionano’s CEO Erik Holmlin and CMO Alka Chaubey, who will discuss highlights from the 2022 global symposium. This event underscores Bionano's global commitment to genomic discovery and expanding its community in China.
Bionano Genomics, known for its innovations in optical genome mapping, has announced that CEO Erik Holmlin will present at the 2022 Maxim Virtual Growth Conference. This event will take place on March 30, 2022, at 12:30 PM PT/3:30 PM ET. The conference can be accessed via the M-Vest platform, where participants can register and view the presentation. Bionano aims to transform genome analysis through its Saphyr® system and NxClinical™ software, addressing critical questions in biology and medicine.
Bionano Genomics is participating in the ACMG Annual Clinical Genetics Meeting from March 23–26, 2022, showcasing its complete product portfolio for the first time. Attendees will include combined teams exhibiting Optical Genome Mapping Solutions, Testing Services, and Software. Six scientific posters will discuss advancements in clinical genetics research, particularly for rare undiagnosed genetic diseases. Bionano aims to support genetic clinicians and researchers with enhanced solutions, promoting discovery and improving diagnostics for patients with genetic disorders.
Bionano Genomics (BNGO) announced the validation of its optical genome mapping (OGM) technology in detecting structural variants (SVs) in hematological neoplasms. The study, involving 59 samples, showed OGM's 98.7% sensitivity and 100% specificity, outperforming traditional methods like karyotyping and FISH. OGM also detected additional chromosomal aberrations in cases where traditional methods failed. Researchers suggested OGM as a potential first-tier test in clinical settings, enhancing the identification of new therapeutic targets. The study reflects increasing evidence for OGM's efficacy in routine use.