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Bionano Genomics, Inc. (Nasdaq: BNGO) is a pioneering company in the life sciences instrumentation sector, dedicated to advancing genome biology understanding through innovative solutions. The company is renowned for its development and marketing of the Saphyr™ system, an ultra-sensitive platform designed for structural variation detection. This system enables researchers and clinicians to accelerate diagnostics and therapeutic target discovery, streamlining studies on chromosomal changes.
Bionano's core mission is to transform genomic analysis through optical genome mapping (OGM) solutions, diagnostic services, and software. Their flagship product, Saphyr™, offers unmatched capabilities in structural variation discovery and the ability to construct comprehensive genome assemblies. This technology is crucial for applications in cancer research, human disease studies, agricultural bioengineering, and genome discovery.
Recent achievements include the detection of unique structural variations and gene fusions in blood cancer samples, underscoring OGM's potential as a complement to traditional sequencing methods. Bionano's OGM technology has shown superior sensitivity and resolution in various studies, highlighting its utility in pediatric leukemia and other cancers.
The company operates globally with significant revenue from the Americas, and it generates product revenue from the sales of OGM and Ionic Purification systems and consumables. Bionano also offers diagnostic testing for neurodevelopmental disabilities through its Lineagen, Inc. d/b/a Bionano Laboratories business and industry-leading genome analysis software that integrates next-generation sequencing and microarray data.
Partnerships with AI-driven companies like Diagens further enhance Bionano's offerings, aiming to improve reproductive health and other clinical applications. Additionally, Bionano continuously upgrades its VIA software and Bionano Solve pipeline to provide researchers with precise and sensitive genomic research tools.
For more information, visit Bionano Genomics and its associated websites, www.bionanolaboratories.com and www.purigenbio.com.
Bionano Genomics (Nasdaq: BNGO) released a validation study showcasing the effectiveness of optical genome mapping (OGM) compared to traditional cytogenetic methods in analyzing hematological neoplasms. The study involved 69 samples and revealed a 100% first-pass rate for OGM, with a sensitivity of 98.7%, specificity of 100%, and accuracy of 99.2%. OGM also identified additional structural variants, aiding better tumor classification and therapy selection. CEO Erik Holmlin expressed optimism about OGM’s potential as a primary cytogenomic test for hematologic malignancies.
Bionano Genomics (Nasdaq: BNGO) will participate in the Association for Molecular Pathology (AMP) Annual Meeting and Expo 2022, showcasing optical genome mapping's (OGM) applications, including genetic disease and hematological malignancies. Key presentations include workshops on enhancing detection of pathogenic structural variants, and methodologies for homologous recombination deficiency assessment. The event will highlight OGM's integration with next-generation sequencing. The conference runs from November 1-5, 2022, in Phoenix, Arizona, underscoring OGM's growing recognition in molecular pathology.
Bionano Genomics (BNGO) will host a conference call and live webcast on November 3, 2022, at 4:30 p.m. ET to discuss its Q3 2022 financial results and corporate advancements. Investors can participate via a toll-free number or through a dedicated webcast link. The call will be accessible for replay on Bionano's investor relations website for 30 days following the event. Bionano Genomics focuses on genome analysis solutions, aiming to enhance diagnostics through its various platforms, including Lineagen and BioDiscovery.
Bionano Genomics, Inc. (BNGO) and Hamilton announced the commercial availability of the Long String VANTAGE, an automated system for high throughput isolation of ultra-high molecular weight (UHMW) DNA. This system improves the efficiency of optical genome mapping (OGM) using human blood samples, allowing labs to process up to 24 samples in an eight-hour workday. Shipping is expected to begin in Q1 2023 as part of ongoing collaboration for clinical applications. The development aims to enhance genomic analysis accuracy, reducing hands-on time and improving result consistency.
Bionano Genomics hosted its first "Meet the User" event on October 24, 2022, at its new CLIA-certified laboratories in San Diego. The event gathered over 50 participants from multiple countries, focusing on optical genome mapping (OGM). Attendees experienced hands-on demonstrations of the Saphyr system and NxClinical software, along with educational sessions on data analysis for rare diseases. Bionano aims to enhance OGM adoption and provided insights into their product roadmap, showcasing the growing interest in genomic solutions.
Bionano Genomics (BNGO) announced its participation in the ASHG Annual Meeting 2022, showcasing its optical genome mapping (OGM) technology. Key presentations include a multi-site clinical study of OGM's application in postnatal genetic disorders and significant advancements in molecular cytogenetics. The conference will feature a record 24 scientific presentations on OGM's utility in genetic disease research. Notably, Bionano will present new data from its partnership with Hamilton on the Long String VANTAGE system, enhancing ultra-high molecular weight DNA extraction processes.
Bionano Genomics (BNGO) announced a peer-reviewed study validating optical genome mapping (OGM) for noninvasive prenatal testing (NIPT) results. The research, conducted at Hangzhou Maternity and Child Care Hospital, found OGM effectively identifies complex chromosomal rearrangements (CCR) tied to recurrent pregnancy loss, with 70% of CCR carriers being phenotypically normal. The study demonstrated OGM's capability to reveal significant structural aberrations overlooked by traditional methods, improving prenatal diagnosis and genetic counseling, highlighting its potential for high-risk pregnancies.
Bionano Genomics (BNGO) announced its participation in the Spanish Society of Hematology (SEHH) 2022 Conference, taking place from October 6-8 in Barcelona. The company featured six scientific presentations showcasing the applications of its optical genome mapping (OGM) technology in hematologic malignancies like leukemias and lymphomas. These independent studies emphasize OGM's utility in cancer genomics and cytogenetic diagnosis, potentially positioning it as a vital tool for future cancer research.
Bionano Genomics (BNGO) announced a study revealing the efficacy of optical genome mapping (OGM) in investigating hepatocellular carcinoma (HCC). Published in Cancer Research, the research demonstrated OGM's capability to detect replication stress-induced structural variations (SVs) more effectively than whole genome sequencing (WGS). The study found that OGM identified 1.4 times more SVs than WGS, illustrating its potential in understanding oncogenesis mechanisms. CEO Erik Holmlin highlighted OGM's sensitivity for large SV detection, emphasizing its complementary role alongside WGS.
Bionano Laboratories and OptraHEALTH have announced a collaboration to integrate the HealthFAX AI platform to enhance genetic counseling services. This initiative aims to improve patient care by automating educational workflows and providing tailored information on genetic testing. The partnership is expected to increase efficiency and scale operations, allowing Bionano Laboratories to better serve patients seeking genetic diagnostics. Both companies emphasize the importance of reducing anxiety for families awaiting genetic test results through improved access to information and support.
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