Welcome to our dedicated page for Bristol-Myers Squibb Co. news (Ticker: BMY), a resource for investors and traders seeking the latest updates and insights on Bristol-Myers Squibb Co. stock.
Bristol-Myers Squibb Co. (BMY) is a renowned American multinational pharmaceutical company headquartered in New York City. As one of the largest pharmaceutical companies globally, Bristol-Myers Squibb (BMS) consistently ranks on the Fortune 500 list. In fiscal 2022, the company achieved total revenue of $46.2 billion.
Bristol-Myers Squibb focuses on discovering, developing, and marketing drugs across various therapeutic areas, including cardiovascular, cancer, and immune disorders. A significant area of focus for BMS is immuno-oncology, where it has established itself as a leader in drug development. Approximately 70% of BMS's total sales are derived from the U.S. market, reflecting its higher dependence on this region compared to its peers.
Recent achievements and collaborations highlight BMS's commitment to innovation and partnerships. On May 22, 2024, BMS joined NeoPhore Limited's oversubscribed Series B extension round. This additional investment will enable NeoPhore to explore novel biology associated with the DNA mismatch repair (MMR) pathway in cancer, and further advance its pre-clinical studies. NeoPhore aims to generate next-generation immuno-oncology therapeutics to improve clinical outcomes for cancer patients.
Another noteworthy collaboration was announced on June 5, 2024, with I-Mab, a U.S.-based global biotech company. This partnership will evaluate the combination of givastomig, an investigational Claudin 18.2 x 4-1BB bispecific antibody, with BMS's immune checkpoint inhibitor, nivolumab, and chemotherapy. The study, a multi-national Phase 1, will focus on advanced Claudin 18.2-positive gastric and esophageal cancers. BMS will supply nivolumab, which is designed to enhance T-cell function and improve anti-tumor responses.
Additionally, on June 5, 2024, Envisagenics, an AI-driven biotechnology company, announced a Series B fundraising round with participation from BMS. This funding will be utilized to further develop Envisagenics' pipeline of novel preclinical oncology assets using their cloud-based AI drug discovery platform, SpliceCore®. This collaboration underscores BMS's continued investment in innovative technologies and therapeutics.
Bristol-Myers Squibb's mission is to discover, develop, and deliver innovative medicines that help patients prevail over serious diseases. Through strategic partnerships, cutting-edge research, and a commitment to therapeutic advancements, BMS continues to make significant strides in the biopharmaceutical industry.
Bristol Myers Squibb (NYSE:BMY) announced positive results from two trials demonstrating Sotyktu (deucravacitinib) efficacy in moderate-to-severe scalp psoriasis and real-world settings. The Phase 3b/4 PSORIATYK SCALP trial showed Sotyktu's superiority over placebo across all primary and secondary endpoints at Week 16. Notably, 48.5% of Sotyktu-treated patients achieved clear/almost clear scalp psoriasis compared to 13.7% on placebo.
The real-world RePhlect registry analysis revealed that six months of Sotyktu treatment was consistent with efficacy outcomes observed in previous clinical studies. Patients achieved significant decreases in disease severity measures, with 67.9% reaching PASI scores ≤3 and 64.1% achieving BSA ≤3%.
Sotyktu's safety profile in PSORIATYK SCALP was consistent with previous trials. These results reinforce Sotyktu as a potential oral standard of care for moderate-to-severe psoriasis, especially with scalp involvement.
PureTech Health announced that KarXT, now marketed as Cobenfy, has received FDA approval for treating schizophrenia in adults. This milestone triggers $29 million in payments to PureTech and unlocks potential future payments and royalties. Cobenfy, invented by PureTech, is the first new drug mechanism approved in over 50 years for schizophrenia treatment.
The approval validates PureTech's unique R&D model, which has now produced three FDA-approved therapeutics. PureTech has generated approximately $1.1 billion from its involvement with Karuna Therapeutics, which was recently acquired by Bristol Myers Squibb. This success enables PureTech to self-fund the advancement of several programs, including LYT-100 for idiopathic pulmonary fibrosis, with topline data expected by year-end.
Bristol Myers Squibb (NYSE: BMY) has received FDA approval for COBENFY™ (xanomeline and trospium chloride), a first-in-class oral medication for treating schizophrenia in adults. This groundbreaking approval marks the first new pharmacological approach to schizophrenia treatment in decades, targeting M1 and M4 receptors without blocking D2 receptors.
The approval is based on the EMERGENT clinical program, which demonstrated significant reductions in schizophrenia symptoms compared to placebo. In Phase 3 trials, COBENFY showed 9.6-point and 8.4-point reductions in PANSS total scores compared to placebo at week five.
COBENFY's safety profile has been established in acute and long-term trials. Common adverse reactions include nausea, dyspepsia, and constipation. The drug does not carry atypical antipsychotic class warnings or a boxed warning.
Bristol Myers Squibb (NYSE: BMY) announced new data from the Phase 3 DAYBREAK trial for Zeposia (ozanimod) in treating relapsing forms of multiple sclerosis. The study demonstrated:
1. Sustained decreased rates of brain volume loss for up to 5 years of continuous treatment.
2. Low and stable rates of whole brain volume loss through Month 60.
3. Declining or stable incidence rates of treatment-emergent adverse events over 8+ years.
4. Consistent reductions in brain volume loss when switching from interferon beta-1a to Zeposia.
The data reinforces Zeposia's established safety and efficacy profile as an effective oral therapy for multiple sclerosis, particularly for newly diagnosed patients.
Bristol Myers Squibb (NYSE: BMY) released 10-year follow-up data from the CheckMate -067 Phase 3 trial showing continued long-term survival benefits of Opdivo® plus Yervoy® in advanced melanoma patients. At ten years, 43% of patients treated with the combination were still alive, compared to a 1-year survival rate of 25% a decade ago. Results showed a median overall survival (OS) of 71.9 months for the combination therapy, 36.9 months for Opdivo alone, and 19.9 months for Yervoy alone. These findings were presented at the ESMO Congress 2024 and published in The New England Journal of Medicine. The study included 945 patients, highlighting that durable clinical benefits were observed across subgroups, including those with BRAF mutant and wild-type tumors. Safety data showed no new adverse signals, and Grade 3/4 treatment-related adverse events were consistent with prior findings.
Bristol Myers Squibb (NYSE: BMY) has announced that it will release its third quarter 2024 financial results on Thursday, October 31, 2024. The company will host a conference call and live webcast at 8:00 a.m. ET on the same day to discuss the results and address questions from investors and analysts. Interested parties can listen to the webcast at http://investor.bms.com or register for the live call. A replay of the webcast and conference call will be available until November 14, 2024. This announcement provides investors and analysts with an opportunity to gain insights into BMY's financial performance and future outlook.
Bristol Myers Squibb (NYSE: BMY) has announced its latest dividend declarations. The Board of Directors has declared a quarterly dividend of $0.60 per share on the company's common stock, payable on November 1, 2024, to stockholders of record as of October 4, 2024. Additionally, a quarterly dividend of $0.50 per share has been declared on the company's convertible preferred stock, payable on December 2, 2024, to stockholders of record as of November 5, 2024. These dividend announcements demonstrate BMY's commitment to returning value to shareholders and maintaining its dividend program.
Bristol Myers Squibb (NYSE: BMY) announced it will present nearly 60 abstracts at the European Society for Medical Oncology (ESMO) Congress 2024 in Barcelona, Spain, from September 13-17.
Key highlights include:
- Data from the Phase 2 RELATIVITY-104 trial indicating the efficacy of nivolumab, relatlimab, and chemotherapy as a first-line treatment for stage IV or recurrent NSCLC.
- Plans to initiate Phase 3 RELATIVITY-1093 trial.
- Ten-year follow-up data from CheckMate-067 showing long-term survival benefits of Opdivo (nivolumab) plus Yervoy (ipilimumab) in advanced melanoma.
- Results from early-phase trials supporting BMS's diverse oncology portfolio and novel combinations across a wide range of solid tumors.
An investor webcast will be hosted on September 14 to discuss these advancements.
Bristol Myers Squibb (NYSE: BMY) employees are embarking on the Coast 2 Coast 4 Cancer (C2C4C) cycling event, aiming to raise $1 million for the V Foundation for Cancer Research. The 3,000-mile relay from Oregon to New Jersey involves teams cycling approximately 225 miles each over three days. Since 2014, C2C4C has raised over $12.7 million for cancer research in North America. Bristol Myers Squibb will match donations up to $500,000. The event has expanded globally, with rides in Europe, Japan, and Latin America, contributing to a total of $16 million USD donated worldwide for cancer research. Many participants have personal connections to cancer, riding in memory of loved ones or as survivors themselves.
Bristol Myers Squibb (NYSE: BMY) announced new long-term follow-up results from the EXPLORER-LTE study of CAMZYOS® (mavacamten) in patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM). The data, presented at the European Society of Cardiology Congress, showed consistent and sustained improvements in echocardiographic measures and symptoms after up to 3.5 years of treatment. Key findings include:
- Reductions in left ventricular outflow tract (LVOT) gradients and left atrial volume index
- Decreased NT-proBNP levels
- Improvement in NYHA class, with 66.3% of patients reaching class I at Week 180
- No new safety signals identified
The results reinforce CAMZYOS's established efficacy and safety profile as the first approved cardiac myosin inhibitor for symptomatic oHCM.
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