bioMérieux Launches GENE-UP® TYPER,an Innovative Diagnostic Solution for Food Industries to Rapidly Analyze the Root Causeof Contamination of Listeria monocytogenes
bioMérieux has launched GENE-UP® TYPER, a real-time PCR solution for rapid pathogen detection and root cause analysis in the food industry. The innovative diagnostic solution helps food manufacturers quickly identify the source of Listeria monocytogenes contamination.
The system combines a specific assay with the AUGMENTED-DX web application, powered by machine learning and a comprehensive genomic database. After pathogen detection and strain isolation, DNA is extracted and amplified, generating analytical results that define unique strain identifiers and group identical strains into clusters. This enables tracking contamination sources and improving production process control.
The solution was developed in collaboration with Mérieux NutriSciences, which will retain co-exclusive rights for testing services. GENE-UP® TYPER LMO, the first assay targeting Listeria monocytogenes, is now available worldwide for food manufacturers.
bioMérieux ha lanciato GENE-UP® TYPER, una soluzione di PCR in tempo reale per la rapida rilevazione di patogeni e l'analisi delle cause radice nell'industria alimentare. Questa innovativa soluzione diagnostica aiuta i produttori alimentari a identificare rapidamente la fonte della contaminazione da Listeria monocytogenes.
Il sistema combina un saggio specifico con l'applicazione web AUGMENTED-DX, alimentata dall'apprendimento automatico e da un ampio database genomico. Dopo la rilevazione del patogeno e l'isolamento del ceppo, il DNA viene estratto e amplificato, generando risultati analitici che definiscono identificatori unici dei ceppi e raggruppano ceppi identici in cluster. Questo consente di tracciare le fonti di contaminazione e migliorare il controllo del processo produttivo.
La soluzione è stata sviluppata in collaborazione con Mérieux NutriSciences, che manterrà diritti co-esclusivi per i servizi di test. GENE-UP® TYPER LMO, il primo saggio mirato a Listeria monocytogenes, è ora disponibile in tutto il mondo per i produttori alimentari.
bioMérieux ha lanzado GENE-UP® TYPER, una solución de PCR en tiempo real para la detección rápida de patógenos y el análisis de la causa raíz en la industria alimentaria. Esta innovadora solución diagnóstica ayuda a los fabricantes de alimentos a identificar rápidamente la fuente de contaminación por Listeria monocytogenes.
El sistema combina un ensayo específico con la aplicación web AUGMENTED-DX, impulsada por el aprendizaje automático y una amplia base de datos genómica. Después de la detección del patógeno y el aislamiento de la cepa, el ADN se extrae y amplifica, generando resultados analíticos que definen identificadores únicos de cepas y agrupan cepas idénticas en grupos. Esto permite rastrear las fuentes de contaminación y mejorar el control del proceso de producción.
La solución se desarrolló en colaboración con Mérieux NutriSciences, que mantendrá derechos co-exclusivos para los servicios de prueba. GENE-UP® TYPER LMO, el primer ensayo dirigido a Listeria monocytogenes, ya está disponible en todo el mundo para los fabricantes de alimentos.
bioMérieux는 식품 산업에서 신속한 병원체 탐지 및 근본 원인 분석을 위한 실시간 PCR 솔루션인 GENE-UP® TYPER를 출시했습니다. 이 혁신적인 진단 솔루션은 식품 제조업체가 Listeria monocytogenes 오염의 원인을 신속하게 식별하는 데 도움을 줍니다.
이 시스템은 특정 분석과 기계 학습 및 포괄적인 유전체 데이터베이스로 구동되는 웹 애플리케이션 AUGMENTED-DX를 결합합니다. 병원체 탐지 및 균주 분리 후, DNA가 추출 및 증폭되어 고유한 균주 식별자를 정의하고 동일한 균주를 클러스터로 그룹화하는 분석 결과를 생성합니다. 이를 통해 오염원의 추적 및 생산 과정의 제어 개선이 가능합니다.
이 솔루션은 Mérieux NutriSciences와 협력하여 개발되었으며, 시험 서비스에 대한 공동 독점 권리를 유지합니다. GENE-UP® TYPER LMO, Listeria monocytogenes를 목표로 하는 첫 번째 분석이 이제 전 세계 식품 제조업체를 위해 제공됩니다.
bioMérieux a lancé GENE-UP® TYPER, une solution de PCR en temps réel pour la détection rapide des pathogènes et l'analyse des causes profondes dans l'industrie alimentaire. Cette solution diagnostique innovante aide les fabricants alimentaires à identifier rapidement la source de contamination par Listeria monocytogenes.
Le système combine un test spécifique avec l'application web AUGMENTED-DX, alimentée par l'apprentissage automatique et une base de données génomique complète. Après la détection du pathogène et l'isolement de la souche, l'ADN est extrait et amplifié, générant des résultats analytiques qui définissent des identifiants de souche uniques et regroupent des souches identiques en clusters. Cela permet de suivre les sources de contamination et d'améliorer le contrôle du processus de production.
La solution a été développée en collaboration avec Mérieux NutriSciences, qui conservera des droits co-exclusifs pour les services de test. GENE-UP® TYPER LMO, le premier test visant Listeria monocytogenes, est désormais disponible dans le monde entier pour les fabricants alimentaires.
bioMérieux hat GENE-UP® TYPER eingeführt, eine Echtzeit-PCR-Lösung zur schnellen Pathogenerkennung und Ursachenanalyse in der Lebensmittelindustrie. Die innovative Diagnoselösung hilft Lebensmittelherstellern, die Quelle der Listeria monocytogenes-Kontamination schnell zu identifizieren.
Das System kombiniert einen spezifischen Test mit der webbasierten Anwendung AUGMENTED-DX, die auf maschinellem Lernen und einer umfassenden genomischen Datenbank basiert. Nach der Pathogenerkennung und dem Isolieren des Stammes wird DNA extrahiert und amplifiziert, was analytische Ergebnisse erzeugt, die einzigartige Stammidentifikatoren definieren und identische Stämme in Cluster gruppieren. Dies ermöglicht das Verfolgen von Kontaminationsquellen und die Verbesserung der Produktionsprozesskontrolle.
Die Lösung wurde in Zusammenarbeit mit Mérieux NutriSciences entwickelt, die die Mitnutzungsrechte für Testdienstleistungen behält. GENE-UP® TYPER LMO, der erste Test, der auf Listeria monocytogenes abzielt, ist nun weltweit für Lebensmittelhersteller verfügbar.
- Launch of innovative diagnostic solution for food safety testing
- Machine learning and genomic database integration for enhanced accuracy
- Global availability of the GENE-UP® TYPER LMO assay
- Strategic partnership with Mérieux NutriSciences for testing services
- None.
Real-Time PCR* Solution Combines an Assay and a Web Application for Rapid Strain Characterization to Quickly Identify Root Cause Contamination Aiding in More Rapid Decision Making to Minimize Future Recurrence
MARCY-L'ÉTOILE,
Each year, an estimated 600 million people fall ill after consuming contaminated food, according to the World Health Organization (WHO)1. These incidents not only pose serious health risks but also lead to costly recalls and reputational damage for food industries. Despite strict monitoring and control measures, contamination can still occur. By using root cause analysis solutions, food industries can identify breakdowns in processes and implement effective corrective actions to better prevent future contaminations.
GENE-UP® TYPER is a real-time PCR solution for rapid strain characterization of microorganisms, for use on bioMérieux's GENE-UP® system. This easy-to-use automated food pathogen detection solution helps speed up the decision-making process by providing faster insights on strain identity.
After a pathogen is detected during routine testing and the strains are isolated in a sample, DNA is extracted and amplified with the GENE-UP® TYPER specific assay. The analytical result generated by the GENE-UP® instrument is then transferred to the AUGMENTED-DX web application. Powered by machine learning, which combines cutting-edge algorithms with years of expertise embedded in a comprehensive genomic database, GENE-UP® TYPER defines a unique address identifying the strain and groups identical strains into "clusters". The web application then progressively builds a history of the strain clusters present in the factory, allowing to trace back the source of contamination for an improved control of the production process.
"With more than 30 years of expertise in Industrial Applications, bioMérieux continues to heavily invest in disruptive science and technology to help the food processing industry keep pace with their rapidly changing environment. With GENE-UP® TYPER, we bring to the market an innovative solution capable of rapidly identifying root causes through genomics and data utilization, participating in the collective effort to make the world a healthier place and fight against food insecurity. With our partner Mérieux NutriSciences, we share the same intent of reshaping the landscape of food safety and set augmented quality standards", explains Yasha Mitrotti, Executive Vice President, Industrial Applications, bioMérieux.
This breakthrough and patented solution has been developed over years of research, with valuable contributions from Mérieux NutriSciences, a long-term partner of bioMérieux belonging to Institut Mérieux as well, and a global leader in food safety, quality and sustainability. Mérieux NutriSciences will retain co-exclusive rights to perform testing in key geographies for the outsourced testing services channel, ensuring the solution is available to all food and beverage processors, whether they operate an internal laboratory or outsource pathogen testing.
GENE-UP® TYPER LMO, the first assay targeting Listeria monocytogenes root causes using the GENE-UP® system, is now available worldwide for food manufacturers.
1 https://www.who.int/activities/estimating-the-burden-of-foodborne-diseases
* Polymerase Chain Reaction
ABOUT BIOMÉRIEUX
Pioneering Diagnostics
A world leader in the field of in vitro diagnostics since 1963, bioMérieux is present in 45 countries and serves more than 160 countries with the support of a large network of distributors. In 2023, revenues reached
bioMérieux provides diagnostic solutions (systems, reagents, software and services) which determine the source of disease and contamination to improve patient health and ensure consumer safety. Its products are mainly used for diagnosing infectious diseases. They are also used for detecting microorganisms in food, pharmaceutical and cosmetic products.
www.biomerieux.com.
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FAQ
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