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Biora Therapeutics, Inc. (Nasdaq: BIOR) is a pioneering biotechnology company focused on revolutionizing therapeutic delivery methods. Headquartered in San Diego, Biora Therapeutics is at the forefront of developing innovative oral biotherapeutics designed to transform patient care. The company is primarily working on two advanced platforms: the NaviCap™ targeted oral delivery platform and the BioJet™ systemic oral delivery platform.
The NaviCap™ platform is tailored for the precise delivery of therapeutics directly to disease sites within the gastrointestinal (GI) tract. This approach aims to enhance treatment outcomes for patients with inflammatory bowel disease (IBD) by increasing therapeutic levels in the affected tissues while minimizing systemic absorption. Notably, Biora's BT-600, a drug-device combination that uses the NaviCap™ device to deliver a unique liquid formulation of tofacitinib, is being developed for the treatment of ulcerative colitis. The positive results from clinical trials highlight the platform's potential to deliver medication specifically to the colon, potentially leading to higher drug efficacy and reduced toxicity.
The BioJet™ platform is designed to replace traditional injections with needle-free, oral delivery of large molecules. This systemic oral delivery system promises to improve chronic disease management by making drug administration more patient-friendly and efficient. The BioJet™ device, roughly the size of a multivitamin, autonomously delivers liquid drugs directly into the small intestine, ensuring optimal drug absorption and bioavailability without the need for complex reformulation.
Financially, Biora Therapeutics has demonstrated resilience and strategic progress. For the fourth quarter of 2023, the company reported a net loss of $15.4 million, a significant improvement from the previous quarter's loss of $73.5 million. This reduction was primarily due to non-recurring charges in the third quarter. Furthermore, the company's operating expenses decreased to $13.3 million in Q4 2023 from $23.3 million in Q3 2023. Biora also successfully raised approximately $6 million through a stock offering, which will support ongoing clinical trials and platform development.
Recent achievements include the issuance of a new patent by the U.S. Patent and Trademark Office, strengthening Biora's intellectual property portfolio for the BioJet™ platform. The company is actively pursuing collaborations and partnerships to further advance its innovative platforms and bring new treatments to market.
With a clear focus on improving patient outcomes and a robust pipeline of innovative products, Biora Therapeutics is poised to make significant strides in the biotechnology sector.
For more information, visit bioratherapeutics.com or follow the company on LinkedIn and Twitter.
Biora Therapeutics, Inc. (Nasdaq: BIOR) will report financial results and provide a corporate update for Q1 2024 on May 15, 2024. The company focuses on therapeutic delivery and will host a webcast and conference call after the market close. Investors can access the call online for 60 days.
Biora Therapeutics, Inc. (Nasdaq: BIOR) will present clinical data on the device function of the NaviCap™ Oral Delivery Platform at Digestive Disease Week 2024. The presentation will include results of human device function studies in healthy volunteers and patients with UC. The abstract will be presented by Shaoying Nikki Lee, PhD, Director of Clinical and Translational Science at Biora Therapeutics, Inc.
Biora Therapeutics, Inc. (Nasdaq: BIOR) announces the completion of dosing for multiple-ascending dose cohorts in the clinical trial of BT-600 for potential treatment of ulcerative colitis. Final results expected in late Q2 2024. The trial evaluated daily doses of BT-600 for seven days at 5 mg and 10 mg tofacitinib or placebo in healthy adult participants. Positive interim results from the single-ascending dose portion have been previously shared.
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