Announces Closing of $5.0 Million Registered Direct Offering and Concurrent Private Placement
Biodexa Pharmaceuticals PLC (Nasdaq: BDRX) has closed a $5.0 million registered direct offering and concurrent private placement. The company raised approximately $4.2 million in net proceeds after expenses. The offering included:
1. 5,050,808 American Depositary Shares (ADS) and 278,975 pre-funded warrants at $0.94 per ADS
2. Unregistered Series J and K warrants to purchase up to 5,329,783 ADSs each
3. Amendment of existing warrants' exercise price to $1.00 per share
Funds will be used for development programs, including a $17 million CPRIT grant match and initiating a Phase 3 trial of eRapa for FAP. Ladenburg Thalmann & Co. Inc. acted as the sole placement agent.
Biodexa Pharmaceuticals PLC (Nasdaq: BDRX) ha completato un'offerta diretta registrata di 5,0 milioni di dollari e una contestuale collocazione privata. L'azienda ha raccolto circa 4,2 milioni di dollari in proventi netti dopo le spese. L'offerta ha incluso:
1. 5.050.808 American Depositary Shares (ADS) e 278.975 warrant prefinanziati a 0,94 dollari per ADS
2. Warrant non registrati di serie J e K per l'acquisto fino a 5.329.783 ADS ciascuno
3. Modifica del prezzo di esercizio dei warrant esistenti a 1,00 dollaro per azione
I fondi saranno utilizzati per programmi di sviluppo, incluso un finanziamento CPRIT di 17 milioni di dollari e l'avvio di un trial di Fase 3 di eRapa per FAP. Ladenburg Thalmann & Co. Inc. ha agito come unico agente di collocamento.
Biodexa Pharmaceuticals PLC (Nasdaq: BDRX) ha cerrado una oferta directa registrada de 5.0 millones de dólares y una colocación privada concurrente. La compañía recaudó aproximadamente 4.2 millones de dólares en ingresos netos después de gastos. La oferta incluyó:
1. 5,050,808 American Depositary Shares (ADS) y 278,975 garantías prefinanciadas a 0.94 dólares por ADS
2. Garantías no registradas de las series J y K para comprar hasta 5,329,783 ADS cada una
3. Modificación del precio de ejercicio de las garantías existentes a 1.00 dólar por acción
Los fondos se utilizarán para programas de desarrollo, incluyendo un subsidio de CPRIT de 17 millones de dólares y el inicio de un ensayo de Fase 3 de eRapa para FAP. Ladenburg Thalmann & Co. Inc. actuó como agente de colocación exclusivo.
Biodexa Pharmaceuticals PLC (Nasdaq: BDRX)가 500만 달러 규모의 등록 직접 공모 및 동시 사모를 마감했습니다. 회사는 비용을 제외하고 약 420만 달러의 순수익을 올렸습니다. 이번 공모에는 다음이 포함되었습니다:
1. 5,050,808개의 미국 예탁 주식(ADS) 및 278,975개의 선행 자금 조달 보증서가 0.94 달러이며
2. 각각 5,329,783개의 ADS를 구매할 수 있는 등록되지 않은 J 및 K 시리즈 보증서
3. 기존 보증서의 행사 가격을 1.00 달러로 수정
모금된 자금은 1700만 달러 CPRIT 보조금 매칭 및 FAP에 대한 eRapa의 3상 시험 시작을 포함한 개발 프로그램에 사용될 예정입니다. Ladenburg Thalmann & Co. Inc.는 유일한 배치 대행사로 활동했습니다.
Biodexa Pharmaceuticals PLC (Nasdaq: BDRX) a clôturé une offre directe enregistrée de 5,0 millions de dollars et une placement privé simultané. La société a collecté environ 4,2 millions de dollars de produits nets après dépenses. L'offre a inclus :
1. 5 050 808 American Depositary Shares (ADS) et 278 975 bons préfinancés à 0,94 dollar par ADS
2. Bons non enregistrés des séries J et K pour acheter jusqu'à 5 329 783 ADS chacun
3. Modification du prix d'exercice des bons existants à 1,00 dollar par action
Les fonds seront utilisés pour des programmes de développement, y compris une subvention de correspondance CPRIT de 17 millions de dollars et le lancement d'un essai de Phase 3 de eRapa pour FAP. Ladenburg Thalmann & Co. Inc. a agi en tant qu'agent de placement exclusif.
Biodexa Pharmaceuticals PLC (Nasdaq: BDRX) hat eine registrierte Direktplatzierung in Höhe von 5,0 Millionen Dollar und eine gleichzeitige private Platzierung abgeschlossen. Das Unternehmen hat nach Abzug der Kosten etwa 4,2 Millionen Dollar an Nettogewinn erzielt. Die Platzierung umfasste:
1. 5.050.808 American Depositary Shares (ADS) und 278.975 vorab finanzierte Warrants zu 0,94 Dollar pro ADS
2. Unregistrierte Warrants der Serien J und K zum Kauf von bis zu 5.329.783 ADS jeweils
3. Änderung des Ausübungspreises bestehender Warrants auf 1,00 Dollar pro Aktie
Die Mittel werden für Entwicklungsprogramme verwendet, darunter ein 17 Millionen Dollar CPRIT Zuschuss und den Start einer Phase-3-Studie von eRapa für FAP. Ladenburg Thalmann & Co. Inc. fungierte als alleiniger Platzierungsagent.
- Raised $4.2 million in net proceeds to fund development programs
- Secured final match payment for a $17 million CPRIT grant
- Initiating Phase 3 clinical trial of eRapa in Familial Adenomatous Polyposis (FAP)
- Potential dilution of existing shareholders due to new share issuance
- Issuance of multiple warrants may lead to future dilution if exercised
- Amendment of existing warrants' exercise price to $1.00 may impact future financing flexibility
Biodexa Pharmaceuticals has successfully raised $5.0 million through a registered direct offering and a concurrent private placement. From a financial standpoint, this influx of capital is significant for a clinical-stage company, providing vital funds to support ongoing and upcoming development programs. The net proceeds of $4.2 million will help fund the company’s match payment for a substantial $17 million grant from the Cancer Prevention Research Institute of Texas (CPRIT) and initiate Phase 3 clinical trials of eRapa in Familial Adenomatous Polyposis (FAP).
This strategic move demonstrates the company’s proactive efforts in securing necessary funds to advance its pipeline. However, investors should be mindful of the dilution effect on the existing shares given the large volume of new shares and warrants issued. It is also essential to consider the Series J and K warrants' exercise prices ($1.00), which might suggest an anticipated appreciation in share value by the company and its investors.
From a market perspective, Biodexa’s offering and subsequent private placement reflect a strong demand for its shares among institutional investors, indicating a positive sentiment toward the company’s future prospects. The involvement of Ladenburg Thalmann & Co. as the sole placement agent enhances the credibility of the offering, suggesting confidence in the company’s strategic direction and clinical programs.
Moreover, the company's decision to amend existing warrants' exercise prices to align with the new ones indicates a potential restructuring strategy aimed at maintaining investor interest and simplifying its financial instruments. This maneuver could strengthen investor relations by creating uniformity in warrant terms and fostering transparency.
Retail investors should note that these financial arrangements aim to fuel significant clinical advancements, potentially leading to breakthrough therapies in unmet medical needs areas. However, the execution of these clinical trials will be pivotal to realizing anticipated value increases.
For those focused on the medical and clinical side, the secured funds are earmarked for the advancement of critical projects such as the Phase 3 clinical trial of eRapa in Familial Adenomatous Polyposis (FAP). This focus on FAP, a condition with limited treatment options, could position Biodexa as a key player in the niche but high-impact area of cancer prevention and treatment.
The alignment with the Cancer Prevention Research Institute of Texas (CPRIT) not only brings substantial funding but also credibility and potential collaborative benefits. Investors should monitor the progress of these clinical trials closely, as successful outcomes could substantially uplift the company's valuation and open doors for further grants and collaborations.
However, it is important to recognize the inherent risks involved in clinical trials, particularly at Phase 3, where outcomes are less predictable. A cautious but optimistic view should be maintained regarding the clinical milestones Biodexa needs to achieve.
July 23, 2024
Biodexa Pharmaceuticals PLC
Announces Closing of
Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (Nasdaq: BDRX), an acquisition-focused clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs, today announced the closing of its previously announced registered direct offering of an aggregate of (i) 5,050,808 American Depositary Shares (the “Depositary Shares”) (each Depositary Share representing 400 of the Company’s ordinary shares, nominal value
The net proceeds from the offering were approximately
In a concurrent private placement, the Company also issued and sold unregistered Series J warrants to purchase up to an aggregate of 5,329,783 Depositary Shares (the “Series J Warrants”) and unregistered Series K warrants to purchase up to an aggregate of 5,329,783 Depositary Shares (the “Series K Warrants”).
The pre-funded warrants have an exercise price of
Ladenburg Thalmann & Co. Inc. acted as sole placement agent in connection with the offering.
In connection with the offering, the Company also agreed to amend the exercise price of existing Series E warrants to purchase an aggregate of 978,233 Depositary Shares, existing Series G warrants to purchase an aggregate of 2,443,995 Depositary Shares and existing Series H warrants to purchase an aggregate of 3,236,345 Depositary Shares that were previously issued in December 2023, May 2022 and May 2022, respectively, held by investors participating in the offering, such that the amended warrants now have an exercise price of
The Depositary Shares (or pre-funded warrants in lieu thereof) were offered pursuant to a shelf registration statement on Form F-3 (File No. 333-267932), which was declared effective by the United States Securities and Exchange Commission (“SEC”) on October 26, 2022. A prospectus supplement relating to the Depositary Shares and pre-funded warrants has been filed with the SEC and is available on the SEC’s website located at http://www.sec.gov. Electronic copies of the prospectus supplement relating to the registered direct offering, together with the accompanying prospectus, may be obtained, when available, from Ladenburg Thalmann & Co. Inc., Prospectus Department, 640 Fifth Avenue, 4th Floor, New York, New York 10019 or by email at prospectus@ladenburg.com.
The private placement of the Series J Warrants and Series K Warrants was made in a transaction not involving a public offering and the securities sold in the private placement have not been registered under the Securities Act of 1933, as amended (the “Securities Act”), or any state or other applicable jurisdiction’s securities laws, and may not be offered or sold in the United States absent registration or an applicable exemption from the registration requirements of the Securities Act and applicable state or other jurisdictions’ securities laws. Pursuant to the securities purchase agreement, the Company has agreed to file a registration statement with the SEC registering the resale of the ordinary shares underlying the Depositary Shares issuable upon the exercise of the Series J Warrants and Series K Warrants issued in the private placement.
This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any offer, solicitation or sale of these securities in any jurisdiction in which such offer, solicitation or sale would be unlawful. Any offering of the securities under the resale registration statement will only be made by means of a prospectus.
About the Cancer Prevention and Research Institute of Texas
CPRIT was created by the Texas Legislature and approved by a statewide vote in 2007 to lead the Lone Star State’s fight against cancer. In 2019, Texas voters again voted overwhelmingly to continue CPRIT with an additional
About Biodexa Pharmaceuticals PLC
Biodexa Pharmaceuticals PLC (listed on NASDAQ: BDRX) is a clinical stage biopharmaceutical company developing a pipeline of innovative products for the treatment of diseases with unmet medical needs. The Company’s lead development programs include eRapa, under development for Familial Adenomatous Polyposis and Non-Muscle Invasive Blader Cancer: tolimidone, under development as a for the treatment of type 1 diabetes; and MTX110, which is being studied in aggressive rare/orphan brain cancer indications.
eRapa is a proprietary oral tablet formulation of rapamycin, also known as sirolimus. Rapamycin is an mTOR (mammalian Target Of Rapamycin) inhibitor. mTOR has been shown to have a significant role in the signalling pathway that regulates cellular metabolism, growth and proliferation and is activated during tumorgenesis.
Tolimidone is an orally delivered, potent and selective inhibitor of Lyn kinase. Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues, liver, and adipose tissue. Tolimidone demonstrates glycemic control via insulin sensitization in animal models of diabetes and has the potential to become a first in class blood glucose modulating agent.
MTX110 is a solubilised formulation of the histone deacetylase (HDAC) inhibitor, panobinostat. This proprietary formulation enables delivery of the product via convection-enhanced delivery (CED) at chemotherapeutic doses directly to the site of the tumor, by-passing the blood-brain barrier and potentially avoiding systemic toxicity.
Biodexa is supported by three proprietary drug delivery technologies focused on improving the bio-delivery and bio-distribution of medicines. Biodexa’s headquarters and R&D facility is in Cardiff, UK. For more information visit www.biodexapharma.com.
Forward-Looking Statements
Certain statements in this announcement may constitute “forward-looking statements” within the meaning of legislation in the United Kingdom and/or United States. Such statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 and are based on management’s belief or interpretation. All statements contained in this announcement that do not relate to matters of historical fact should be considered forward-looking statements including, but not limited to, the anticipated net proceeds, and the anticipated use of proceeds therefrom, and projected cash runway. In certain cases, forward-looking statements can be identified by the use of words such as “plans”, “expects” or “does not anticipate”, or “believes”, or variations of such words and phrases or statements that certain actions, events or results “may”, “could”, “would”, “might” or “will be taken”, “occur” or “be achieved.” Forward-looking statements and information are subject to various known and unknown risks and uncertainties, many of which are beyond the ability of the Company to control or predict, that may cause their actual results, performance or achievements to be materially different from those expressed or implied thereby, and are developed based on assumptions about such risks, uncertainties and other factors set out herein.
Reference should be made to those documents that Biodexa shall file from time to time or announcements that may be made by Biodexa in accordance with the rules and regulations promulgated by the SEC, which contain and identify other important factors that could cause actual results to differ materially from those contained in any projections or forward-looking statements. These forward-looking statements speak only as of the date of this announcement. All subsequent written and oral forward-looking statements by or concerning Biodexa are expressly qualified in their entirety by the cautionary statements above. Except as may be required under relevant laws in the United States, Biodexa does not undertake any obligation to publicly update or revise any forward-looking statements because of new information, future events or events otherwise arising.
For more information, please contact:
Biodexa Pharmaceuticals PLC |
Stephen Stamp, CEO, CFO Tel: +44 (0)29 20480 180 www.biodexapharma.com |
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