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Atea Pharmaceuticals, Inc. (NASDAQ: AVIR) is a clinical-stage biopharmaceutical company based in Boston, Massachusetts, dedicated to discovering, developing, and commercializing oral antiviral therapies aimed at treating severe viral diseases. Founded in 2012, Atea focuses on addressing unmet medical needs, particularly in serious viral infections caused by single-stranded RNA viruses.
The company's leading product candidate is AT-527 (bemnifosbuvir), an antiviral agent developed for treating COVID-19, caused by the SARS-CoV-2 virus. Currently, AT-527 is undergoing Phase 3 clinical trials. Additionally, the combination of bemnifosbuvir and ruzasvir, an oral NS5A inhibitor, is being developed for treating Hepatitis C Virus (HCV) and has shown promising results in Phase 2 trials. This combination therapy aims to provide a highly potent pan-genotypic antiviral treatment with a short treatment duration and fewer contraindications, particularly beneficial for HCV patients.
Beyond COVID-19 and HCV, Atea is also advancing other antiviral therapies in its pipeline, including AT-787 for Hepatitis C (under Phase 2 clinical trial), AT-752 for Dengue (under Phase 2 trial), and other candidates like AT-889 and AT-934 for Respiratory Syncytial Virus (currently under clinical trials).
Recent achievements include positive initial data from a Phase 2 study of bemnifosbuvir and ruzasvir for HCV, showing a 97% sustained virologic response rate at 12 weeks post-treatment. Furthermore, Atea has completed enrollment for the Phase 3 SUNRISE-3 trial for treating high-risk COVID-19 patients, with results expected in the second half of 2024.
Financially, Atea reported a solid cash position of $578.1 million as of December 31, 2023, enabling them to continue advancing their clinical programs. Collaborations and strategic partnerships play a crucial role in Atea’s progress, helping to broaden its scope and enhance its therapeutic offerings.
Investors and stakeholders can stay informed about Atea’s developments through their regular updates, financial reports, and participation in industry conferences. For more information, visit their official website at www.ateapharma.com.
Atea Pharmaceuticals (Nasdaq: AVIR) announced that CEO Jean-Pierre Sommadossi will present a corporate overview at the Jefferies Healthcare Conference on June 8, 2022, at 11:00 a.m. ET. A live webcast will be accessible on their website, and a replay will be available for 90 days. Atea is a clinical-stage biopharmaceutical company focused on developing oral antiviral therapies for serious diseases, including COVID-19 and HCV, utilizing its proprietary nucleos(t)ide prodrug platform. The company emphasizes its commitment to addressing unmet medical needs in severe viral infections.
Atea Pharmaceuticals (AVIR) announced new clinical results from the MORNINGSKY trial, indicating a 71% reduction in hospitalization for COVID-19 patients treated with bemnifosbuvir (AT-527) compared to placebo (p=0.047). The Phase 2 study in high-risk patients also showed no deaths among those treated with bemnifosbuvir. The company initiated a Phase 2 global study for AT-752 targeting dengue and is preparing for a combination study of bemnifosbuvir and ruzasvir for hepatitis C in 2H 2022. Atea reported a net loss of $42.1 million for Q1 2022.
Atea Pharmaceuticals (Nasdaq: AVIR) will host a live conference call on May 10, 2022, at 8:00 a.m. ET to share financial results for Q1 ended March 31, 2022, and provide a business update. Investors can access the call by dialing (800) 343-5172 domestically or (203) 518-9814 internationally, with conference ID AVIRQ122. A live audio webcast and slide presentation will be available on Atea's website.
Atea focuses on developing oral antiviral therapies for severe viral diseases, including COVID-19 and hepatitis C.
Atea Pharmaceuticals presented favorable nonclinical data for bemnifosbuvir (AT-527) at the SOT 61st Annual Meeting in San Diego. The company reported a nonclinical safety profile with no reproductive or developmental toxicity in animal models. This includes:
- No effects on fertility or reproduction in rats.
- No embryofetal abnormalities in rabbits at high doses.
- Low potential for QTc prolongation in both rats and monkeys.
CEO Jean-Pierre Sommadossi emphasized its suitability for clinical development against severe viral infections, including COVID-19 and hepatitis C.
Atea Pharmaceuticals (Nasdaq: AVIR) reported strong financial results for Q4 and the full year 2021, with collaboration revenue of $192.2 million and total revenue of $351.4 million, significantly up from $48.6 million in 2020. The net income was $117.1 million, compared to $20.7 million in the previous year. Atea is advancing three Phase 2 programs targeting COVID-19, hepatitis C, and dengue fever, and anticipates important milestones in 2022. With cash reserves of $764.4 million, the company is well-positioned to fund ongoing developments.
Atea Pharmaceuticals (Nasdaq: AVIR) will host a live conference call and audio webcast on February 28, 2022, at 4:30 p.m. ET. This event will report the fourth-quarter and full-year financial results for 2021, and provide a business update. Atea, focused on developing oral therapies for severe viral diseases, aims to address unmet medical needs, particularly for infections like COVID-19 and hepatitis C. Following the live call, an archived version will be accessible on the company’s website.
Atea Pharmaceuticals has appointed Nancy Gail Berry Agrawal, Ph.D., as Executive Vice President of Preclinical Development, enhancing its expertise in drug discovery and development. Dr. Agrawal, with over 25 years of experience at Merck, replaces Steven Good, who will retire this year. Her extensive background in developing antivirals aligns with Atea's mission to create oral therapies for severe viral diseases. The company is focused on expanding its pipeline, including treatments for COVID-19, hepatitis C, dengue, and RSV.
BOSTON, Feb. 09, 2022 – Atea Pharmaceuticals, Inc. (Nasdaq: AVIR) announced that CEO Jean-Pierre Sommadossi and the management team will present a business update at the 11th Annual SVB Leerink Global Healthcare Conference on February 17, 2022, at 2:20 p.m. ET. A live webcast of the event will be accessible on the company’s website, with a replay available for 90 days. Atea focuses on developing oral therapies for severe viral diseases, including SARS-CoV-2 and hepatitis C, utilizing a proprietary nucleotide prodrug platform.
Atea Pharmaceuticals has announced new findings published in Nature Communications regarding its antiviral drug bemnifosbuvir (AT-527). The data reveal that bemnifosbuvir's unique dual mechanism targets both chain termination and nucleotidylyltransferase inhibition, which may create a significant barrier to viral resistance. In Phase 2 trials, the drug has shown rapid antiviral activity and is generally safe for high-risk COVID-19 patients. This positions bemnifosbuvir as a promising option for treating COVID-19 and other viral diseases, according to Atea's leadership.
Atea Pharmaceuticals (AVIR) is advancing its clinical development strategy with plans for a global Phase 2 outpatient trial of bemnifosbuvir (AT-527) for COVID-19. The company has also secured exclusive worldwide rights to ruzasvir (RZR) from Merck, aiming to combine it with bemnifosbuvir for hepatitis C treatment. Furthermore, Atea is launching a Phase 2 proof-of-concept program for AT-752 targeting dengue fever. The Phase 2 COVID-19 trial will enroll 200 high-risk outpatients, with topline data expected in late 2022.
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