Welcome to our dedicated page for Actinium Pharmaceuticals news (Ticker: ATNM), a resource for investors and traders seeking the latest updates and insights on Actinium Pharmaceuticals stock.
Actinium Pharmaceuticals, Inc. (NYSE MKT: ATNM) is a New York-based biopharmaceutical company focused on developing innovative targeted radiotherapies for the treatment of advanced cancers. Leveraging its proprietary delivery platform, Actinium utilizes alpha-emitting Actinium-225 and Bismuth-213, as well as certain beta-emitting radiopharmaceuticals, in conjunction with monoclonal antibodies to target and kill cancer cells. The company’s leading product candidate, Iomab™-B, is designed to prepare patients for hematopoietic stem cell transplants (bone marrow transplants) by delivering targeted radiotherapy directly to the bone marrow. Iomab™-B is currently in a pivotal, multicenter Phase 3 clinical study for refractory and relapsed acute myeloid leukemia (AML) patients over the age of 55, focusing on durable complete remission as its primary endpoint.
Actinium's second key program, Actimab-A, is undergoing clinical development in Phase 1/2 trials for newly diagnosed AML patients. This program utilizes Actinium-225 and aims to improve outcomes for patients who have failed existing therapies. Actinium is also involved in numerous partnerships and collaborations, such as with Astellas Pharma, AVEO Oncology/LG Chem Life Sciences, and others, to expand its reach in the realm of radiotherapy for solid tumors.
The company has demonstrated promising results in various studies, including the Phase 3 SIERRA trial for Iomab™-B, which showed significant improvements in survival rates among high-risk AML patients, particularly those with TP53 mutations. Further, Actinium's proprietary cyclotron technology for producing Actinium-225 at commercial scale holds potential for reducing production costs and enhancing supply for clinical and commercial purposes. With a robust pipeline and a strong patent portfolio comprising over 230 patents and applications, Actinium Pharmaceuticals continues to make strides in the field of targeted radiotherapies.
For more information, visit Actinium Pharmaceuticals, Inc.
Actinium Pharmaceuticals, Inc. (NYSE: ATNM) will participate in the virtual Bio-Europe conference from November 2-4, 2022. The event is the largest biopharma partnering meeting in Europe, featuring over 4,000 attendees and 27,000 scheduled 1-on-1 meetings. Actinium's business development team will conduct individual meetings, which can be requested through the partneringONE® system. The company focuses on targeted radiotherapies for cancer treatment, with key products including I-131 apamistamab (Iomab-B) and Actimab-A, both undergoing clinical trials.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) has appointed several key executives to strengthen its leadership team. Jenny Hsieh joins as Chief Strategy Officer, having previously led corporate strategy at Immunomedics. Sunitha Lakshminarayanan takes on the role of Senior Vice President, Head of CMC and Product Development, bringing extensive experience from Bristol Myers Squibb. Stephen Dressel is appointed Vice President of Strategic Finance and Analysis, with a background in finance at Regeneron. These additions come as the company prepares for pivotal clinical data results from the Iomab-B SIERRA trial and Actimab-A CLAG-M combination trial.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) announced its participation at the Cantor Fitzgerald Oncology, Hematology & HemOnc Conference on September 28, 2022. Chief Medical Officer Dr. Avinash Desai will join a panel discussing "Addressing Challenges in Cell Therapy and Transplant" at 9:00 AM ET. The conference will be held at the Lotte New York Palace Hotel, where Actinium's executive team will also be available for one-on-one meetings. The company is focused on developing targeted radiotherapies to improve cancer treatment outcomes.
Actinium Pharmaceuticals (NYSE: ATNM) provided a corporate update on September 21, 2022, highlighting key upcoming milestones in its clinical pipeline. Key data releases expected include topline results from the pivotal Phase 3 SIERRA trial for Iomab-B and overall survival data from the Actimab-A CLAG-M combination trial, both anticipated in Q4 2022. The company reported approximately $116 million in cash and equivalents as of Q2 2022, sufficient to support operations through mid-2025, facilitating its commitment to advancing targeted radiotherapies for patients with high unmet medical needs.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) will participate in the H.C. Wainwright 24th Annual Global Investment Conference from September 12-14, 2022. The hybrid event will take place at the Lotte New York Palace Hotel and online. Management will conduct one-on-one meetings and an investor presentation will be accessible on the conference and company websites. Actinium specializes in targeted radiotherapies for cancer treatment, with notable projects like I-131 apamistamab aimed at enhancing patient outcomes and reducing treatment toxicities.
Actinium Pharmaceuticals, Inc. (NYSE AMERICAN: ATNM) presented pivotal data from its Phase 3 SIERRA trial of Iomab-B at the TCT Meeting. The trial demonstrated that 100% of patients receiving Iomab-B accessed bone marrow transplants (BMT) compared to only 18% in the control arm. Additionally, Iomab-B showed lower rates of transplant-related mortality and sepsis. Notably, 82% of the control arm did not achieve the primary endpoint of durable complete remission. Topline results are anticipated in Q3 2022, aiming to bolster Iomab-B's position as a critical therapy for acute myeloid leukemia (AML) patients.
Actinium Pharmaceuticals (ATNM) is set to present updated Phase 3 SIERRA trial data at the TCT Tandem Meetings from April 23-26, 2022. This trial focuses on Iomab-B, a targeted radiotherapy designed for elderly patients with relapsed or refractory acute myeloid leukemia (AML), aiming for successful bone marrow transplants. Early data indicates a 100% access rate to transplantation and improved outcomes compared to conventional therapies. The findings will be showcased by Boglarka Gyurkocza from Memorial Sloan Kettering Cancer Center, highlighting Iomab-B's potential to revolutionize patient treatment pathways.
Actinium Pharmaceuticals (NYSE AMERICAN: ATNM) has entered a licensing agreement with Immedica for Iomab-B, an antibody-radiation conjugate aimed at treating acute myeloid leukemia (AML). Actinium will receive an upfront payment of $35 million and could earn up to $452 million in milestone payments, plus mid-twenty percent royalties on sales. Iomab-B is expected to facilitate bone marrow transplants, addressing a significant medical need in Europe, the Middle East, and North Africa. The Phase 3 SIERRA trial's topline results are anticipated in Q3 2022.
Actinium Pharmaceuticals (NYSE: ATNM) announced promising preclinical results for its anti-HER3 antibody conjugated with Ac-225, aimed at treating HER3-positive non-small cell lung cancer (NSCLC). Studies demonstrated enhanced anti-tumor effects and improved survival in NSCLC models compared to traditional HER3 antibodies. The findings were presented at AACR 2022, emphasizing the potential of HER3-targeted radiotherapy as a novel treatment strategy. Actinium's collaboration with AVEO Oncology further supports the development of this radiotherapy.
Actinium Pharmaceuticals, Inc. (NYSE AMERICAN: ATNM) presented preclinical data at the AACR 2022 highlighting the efficacy of combining its Ac-225-HER3 antibody radiation conjugate with Gilead's magrolimab, an anti-CD47 antibody. The study demonstrated significant tumor control improvement in HER3-positive models compared to magrolimab alone. The data suggests enhanced phagocytosis and upregulation of calreticulin, indicating stronger anti-tumor responses. Actinium aims to further develop this combination for treating solid tumors and blood cancers, leveraging its technology and strategic collaborations.
FAQ
What is the current stock price of Actinium Pharmaceuticals (ATNM)?
What is the market cap of Actinium Pharmaceuticals (ATNM)?
What is Actinium Pharmaceuticals' primary focus?
What are the main product candidates of Actinium Pharmaceuticals?
What is unique about Actinium's delivery platform?
What are the recent achievements of Actinium Pharmaceuticals?
Who are some of Actinium Pharmaceuticals' key partners?
What are the benefits of Actinium's cyclotron technology?
What is Iomab™-B used for?
What is the significance of the SIERRA trial?
How extensive is Actinium's patent portfolio?
Where can I find more information about Actinium Pharmaceuticals?
