Welcome to our dedicated page for Alterity Therapeutics news (Ticker: ATHE), a resource for investors and traders seeking the latest updates and insights on Alterity Therapeutics stock.
Alterity Therapeutics Ltd (ATHE) is a clinical-stage biotechnology company pioneering treatments for neurodegenerative disorders including Parkinson's and Alzheimer's diseases. This page serves as the definitive source for verified updates on the company's therapeutic developments, research milestones, and strategic initiatives.
Investors and researchers will find timely updates on ATH434 clinical trials, partnership announcements with leading medical institutions, and regulatory progress for novel drug candidates. Our curated news collection provides essential context for understanding Alterity's approach to targeting iron dysregulation in neurological conditions and its broader research pipeline.
Key content includes updates on:
- Phase I/II clinical trial results
- Collaborative research initiatives
- Peer-reviewed study publications
- Regulatory pathway developments
- Scientific conference presentations
Bookmark this page for structured access to Alterity Therapeutics' latest advancements in neuroprotective therapies. Check regularly for objective reporting on the company's progress in addressing complex neurodegenerative challenges through innovative biomedical research.
Alterity Therapeutics (ASX: ATH, NASDAQ: ATHE) announced the granting of a new composition of matter patent from the USPTO, covering a class of iron chaperones aimed at redistributing excess iron in the central nervous system. This patent secures a monopoly over 150 pharmaceutical compositions targeting neurodegenerative diseases such as Alzheimer's and Parkinson's. The company plans to launch a Phase 2 trial for its lead candidate, ATH434, by year-end, which is developed for Multiple System Atrophy (MSA) and is expected to advance their drug development efforts.
Alterity Therapeutics has received positive guidance from the European Medicines Agency (EMA) for its Phase 2 clinical trial of ATH434 targeting Multiple System Atrophy (MSA). The EMA supports recruiting early-stage MSA patients and the use of biomarkers to identify them. Alterity aims to utilize the EMA's feedback to improve trial design, aiming to generate robust data for regulatory authorities. The trial is set to launch in the second half of the year, focusing on a disease modifying approach as no approved treatment currently exists for MSA.
Alterity Therapeutics Limited (NASDAQ: ATHE) reported a cash balance of $32.8M for Q3 FY21, with operational cash outflows of $5M. The company received a $495K grant from the Michael J. Fox Foundation for Parkinson's disease research related to its lead drug candidate, ATH434. Progress continues on the Phase 2 trial for ATH434, with 80% of the target population recruited in a related study at Vanderbilt University. Dr David Stamler was appointed CEO, succeeding Geoffrey Kempler.
Alterity Therapeutics (ASX: ATH, NASDAQ: ATHE) announced an oral presentation at the American Academy of Neurology conference on April 21, 2021, regarding its lead compound ATH434, aimed at treating Parkinsonian disorders. The presentation showed that ATH434 is neuroprotective, preserving neurons in critical brain regions and improving motor function in an animal model of Multiple System Atrophy (MSA). The findings provide further evidence of ATH434's potential as a disease-modifying treatment, supported by data showing reductions in toxic α-synuclein levels and improved coordination.
Alterity Therapeutics Limited (ASX: ATH, NASDAQ: ATHE) will present at the 7th International Congress of Multiple System Atrophy (MSA2021) on February 26-27, 2021. This premier virtual event focuses on MSA, a severe neurodegenerative disease without an approved treatment. Alterity will showcase data on ATH434, its lead candidate, highlighting its safety profile concerning blood pressure regulation—a critical factor in MSA. The company is also conducting a natural history study in partnership with Vanderbilt University to support future treatment studies.
Alterity Therapeutics (NASDAQ: ATHE) announced a grant of US$495,000 from The Michael J. Fox Foundation for Parkinson's Research on February 9, 2021. This funding aims to evaluate the pharmacologic profile of ATH434, targeting optimal dosing in future clinical trials for Parkinson's disease. This marks the second grant from the Foundation to support ATH434's development. ATH434 aims to modify alpha-synuclein misfolding, which could impact symptoms of Parkinson's disease and related disorders. The project will utilize primate models to determine dosing in upcoming trials.
Alterity Therapeutics announced the appointment of Dr. David Stamler as CEO, effective immediately. Dr. Stamler, who joined the company in June 2017, has extensive experience in pharmaceutical development, specifically in neurological treatments. He succeeds Geoffrey Kempler, who will transition to Non-Executive Chairman and remain as a consultant. This leadership change coincides with the advancement of Alterity's lead compound, ATH434, into Phase 2 clinical trials. ATH434 has been granted Orphan designation by the US FDA for treating Multiple System Atrophy.
Alterity Therapeutics (ASX: ATH, NASDAQ: ATHE) has secured an exclusive license from UniQuest to develop novel zinc ionophore technology aimed at fighting antimicrobial resistance to superbugs. This technology, which utilizes Alterity's PBT2, allows for the re-sensitization of bacteria to antibiotics, addressing a critical health issue. PBT2 has shown potential in reversing antibiotic resistance in preclinical studies and is patented until 2038. The partnership with UniQuest may significantly enhance Alterity's commercial prospects while maintaining focus on its primary program for ATH434.
Alterity Therapeutics (ATHE) announced the allowance of a new patent by the USPTO, covering over 150 novel compounds aimed at treating neurodegenerative diseases such as Parkinson's and Alzheimer's. This patent grants 20 years of exclusivity, bolstering the company's drug development portfolio. Alterity's lead candidate, ATH434, shows promise in clinical development, demonstrating favorable safety and efficacy in animal models. CEO Geoffrey Kempler emphasized the significance of this patent in pursuing innovative therapeutic options for serious brain diseases.
Alterity Therapeutics (ASX: ATH, NASDAQ: ATHE) announced the start of patient enrollment for its bioMUSE Study focusing on Multiple System Atrophy (MSA) on Oct. 26, 2020. The study, conducted in collaboration with Vanderbilt University Medical Center, aims to track disease progression in early-stage MSA patients. The bioMUSE study data will inform the upcoming Phase 2 clinical trial of Alterity's lead compound, ATH434, which has completed Phase 1 trials. MSA is a debilitating neurodegenerative condition with no approved therapies, making this study crucial for advancing treatment options.
