Arrowhead Files for Regulatory Clearance to Initiate Phase 1/2a Study of ARO-RAGE for Treatment of Asthma
Arrowhead Pharmaceuticals (NASDAQ: ARWR) has submitted an application to initiate a Phase 1/2a clinical trial for ARO-RAGE, an investigational RNA interference therapeutic aimed at treating asthma and inflammatory pulmonary diseases. This innovative treatment targets the receptor for advanced glycation end products (RAGE). The application has been sent to both a local Ethics Committee and New Zealand's Medicines Authority. The upcoming study will assess the safety, tolerability, and pharmacokinetics of ARO-RAGE in 64 healthy volunteers and 16 asthma patients.
- Submission of application for Phase 1/2a trial of ARO-RAGE indicates progress in drug development.
- ARO-RAGE targets RAGE, a key mediator in asthma inflammation, potentially offering a new treatment option.
- Use of innovative TRiM™ platform for pulmonary delivery of the RNAi therapeutic.
- None.
An application for approval of the clinical trial was submitted to a local Ethics Committee and to the
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