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Arrowhead Earns $10 Million Option Exercise Fee

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Arrowhead Pharmaceuticals (NASDAQ: ARWR) reported that Janssen Pharmaceuticals has exercised its option for ARO-JNJ1, leading to a $10 million option exercise fee for Arrowhead. This agreement, part of a collaboration initiated in 2018, allows Janssen to develop and commercialize ARO-JNJ1, an RNAi therapeutic candidate. Arrowhead anticipates additional milestone payments and royalties from the commercial sales of ARO-JNJ1. The CEO expressed optimism about the collaboration, highlighting its productivity in addressing chronic hepatitis B and potential future programs.

Positive
  • Arrowhead receives a $10 million option exercise fee from Janssen.
  • Janssen will develop and commercialize ARO-JNJ1, enhancing Arrowhead's revenue potential.
  • Potential for additional milestone payments and royalties on ARO-JNJ1 sales.
Negative
  • None.

Arrowhead Pharmaceuticals Inc. (NASDAQ: ARWR) today announced that Janssen Pharmaceuticals, Inc., (Janssen) part of the Janssen Pharmaceutical Companies of Johnson & Johnson, has delivered written notice of its intent to exercise its option right for ARO-JNJ1. Receipt of the option notice earns Arrowhead a $10 million option exercise fee and grants Janssen all rights, including licenses, and obligations to develop and commercialize ARO-JNJ1, an investigational RNAi therapeutic candidate which utilizes Arrowhead’s proprietary Targeted RNAi Molecule (TRiM) platform.

Chris Anzalone, Ph.D., president and chief executive officer at Arrowhead, said: “The collaboration with Janssen, which was executed in 2018, for ARO-HBV against chronic hepatitis B infection, and potentially three additional programs, has been highly productive and collaborative. We are thrilled that Janssen has decided to exercise its option on ARO-JNJ1 and move forward with clinical studies. We look forward to continued collaboration and progress as Janssen advances these potentially important new medicines.”

Arrowhead entered into a license and collaboration agreement, and into a research collaboration and option agreement, with Janssen in October 2018. Arrowhead is eligible for additional payments when future milestones are met and is also eligible for royalties on commercial sales of ARO-JNJ1.

About Arrowhead Pharmaceuticals

Arrowhead Pharmaceuticals develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

For more information, please visit www.arrowheadpharma.com, or follow us on Twitter @ArrowheadPharma. To be added to the Company's email list and receive news directly, please visit http://ir.arrowheadpharma.com/email-alerts.

Safe Harbor Statement under the Private Securities Litigation Reform Act:

This news release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Any statements contained in this release except for historical information may be deemed to be forward-looking statements. Without limiting the generality of the foregoing, words such as “may,” “will,” “expect,” “believe,” “anticipate,” “intend,” “plan,” “project,” “could,” “estimate,” or “continue” are intended to identify such forward-looking statements. In addition, any statements that refer to projections of our future financial performance, trends in our businesses, or other characterizations of future events or circumstances are forward-looking statements. These statements are based upon our current expectations and speak only as of the date hereof. Our actual results may differ materially and adversely from those expressed in any forward-looking statements as a result of numerous factors and uncertainties, including the continuing impact of the COVID-19 pandemic, the safety and efficacy of our product candidates, the duration and impact of regulatory delays in our clinical programs, our ability to finance our operations, the likelihood and timing of the receipt of future milestone and licensing fees, the future success of our scientific studies, our ability to successfully develop and commercialize drug candidates, the timing for starting and completing clinical trials, rapid technological change in our markets, the enforcement of our intellectual property rights, and the other risks and uncertainties described in our most recent Annual Report on Form 10-K, subsequent Quarterly Reports on Form 10-Q and other documents filed with the Securities and Exchange Commission from time to time. We assume no obligation to update or revise forward-looking statements to reflect new events or circumstances.

Source: Arrowhead Pharmaceuticals, Inc.

FAQ

What is the recent development involving Arrowhead Pharmaceuticals and Janssen Pharmaceuticals?

Janssen Pharmaceuticals has exercised its option for ARO-JNJ1, resulting in a $10 million option exercise fee for Arrowhead.

How much is Arrowhead Pharmaceuticals earning from the option exercise by Janssen?

Arrowhead Pharmaceuticals is earning a $10 million option exercise fee from Janssen.

What is ARO-JNJ1 in relation to Arrowhead Pharmaceuticals?

ARO-JNJ1 is an investigational RNAi therapeutic candidate developed under Arrowhead's proprietary Targeted RNAi Molecule (TRiM) platform.

When was the collaboration agreement between Arrowhead and Janssen established?

The collaboration agreement between Arrowhead and Janssen was established in October 2018.

What are the potential future financial benefits for Arrowhead Pharmaceuticals from the Janssen collaboration?

Arrowhead may receive additional milestone payments and royalties on the commercial sales of ARO-JNJ1.

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