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Apellis Pharmaceuticals, Inc. - APLS STOCK NEWS

Welcome to our dedicated page for Apellis Pharmaceuticals news (Ticker: APLS), a resource for investors and traders seeking the latest updates and insights on Apellis Pharmaceuticals stock.

Apellis Pharmaceuticals, Inc. (Nasdaq: APLS) is a commercial-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of novel therapeutic compounds. The company's primary focus is on treating diseases with high unmet medical needs through the inhibition of the complement system, a crucial part of the immune system. Apellis targets the complement system at the level of C3, aiming to provide comprehensive disease control.

Apellis's flagship products include SYFOVRE® (pegcetacoplan injection) and EMPAVELI® (pegcetacoplan). SYFOVRE is the first-ever approved therapy for geographic atrophy (GA), a leading cause of blindness, while EMPAVELI is approved for treating paroxysmal nocturnal hemoglobinuria (PNH), a rare hematological disease. Both medicines reflect the company's innovative approach to complement immunotherapy.

In 2023, Apellis achieved significant milestones, including generating $397 million in revenue, with substantial contributions from SYFOVRE and EMPAVELI. The company has also presented positive data from its Phase 2 NOBLE study for systemic pegcetacoplan in rare kidney diseases at the European Renal Association Congress, highlighting the potential of pegcetacoplan to address complex medical conditions.

Looking ahead, Apellis anticipates regulatory developments, including the European Medicines Agency’s (EMA) review of the marketing authorization application (MAA) for SYFOVRE and the expected topline data from the Phase 3 VALIANT study of systemic pegcetacoplan in mid-2024. Financially robust, Apellis recently closed a $375 million funding deal with Sixth Street to buy out existing liabilities, significantly improving its liquidity profile and positioning the company for sustainable growth.

Apellis's commitment to advancing science is evident through its extensive pipeline and collaborations, such as its partnership with Sobi for systemic pegcetacoplan. The company's approach combines bold scientific endeavors with compassionate patient care, continually striving to bring life-changing therapies to those in need.

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Apellis Pharmaceuticals (Nasdaq: APLS) announced the approval of equity inducement awards to seven new employees on April 3, 2023. The awards, totaling 16,115 restricted stock units (RSUs), are designed to incentivize new hires as part of their employment acceptance. The RSUs will vest in increments of 25% annually over four years, contingent upon continued employment. This move aligns with Nasdaq Listing Rule 5635(c)(4) and reflects the company's strategy to attract talent in the biopharmaceutical sector, particularly in complement medicine.

As a leader in this field, Apellis aims to innovate therapies for rare and neurological diseases. The company is committed to developing transformative medicines and enhancing its workforce to support ongoing research and development efforts.

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Apellis Pharmaceuticals (Nasdaq: APLS) announced on March 6, 2023, the approval of equity awards for six new employees, granted on March 1, 2023. The awards, consisting of 19,495 restricted stock units (RSUs), are part of the 2022 Inducement Stock Incentive Plan and were essential for the employees’ acceptance of their positions. Each RSU will vest in increments of 25% annually, contingent on continuous employment. This move aligns with Nasdaq Listing Rule 5635(c)(4) and showcases Apellis’ commitment to attracting talent for advancing its work in complement medicine.

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Apellis Pharmaceuticals, a leader in complement medicine, announced its participation in two upcoming March investor conferences:

  • Cowen 43rd Annual Healthcare Conference: Fireside chat on March 8, 2023, at 9:10 a.m. ET.
  • Oppenheimer’s 33rd Annual Healthcare Conference: Virtual fireside chat on March 13, 2023, at 3:20 p.m. ET.

Both events will have live webcasts available on the company’s website, with replays accessible for 90 days. Apellis focuses on innovative therapies aimed at complex diseases, boasting two approved medications for targeting complement C3. For more details, visit apellis.com.

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Apellis Pharmaceuticals, Inc. (Nasdaq: APLS) has completed its underwritten public offering, raising approximately $402.5 million through the sale of 4,007,936 shares of common stock priced at $63.00 per share, along with pre-funded warrants for 2,380,956 shares. The offering includes an additional 833,333 shares due to underwriters' full exercise of their option. The funds will support Apellis' commitment to developing innovative therapies. J.P. Morgan, Goldman Sachs, and Evercore served as joint book-running managers for the offering, which was facilitated under an automatically effective shelf registration statement.

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Apellis Pharmaceuticals (Nasdaq: APLS) announced the pricing of its public offering of 3,174,603 shares of common stock at $63.00 per share, and 2,380,956 pre-funded warrants at $62.9999 each, totaling approximately $350 million gross proceeds before deductions. The offering is set to close on February 27, 2023, pending customary conditions. J.P. Morgan, Goldman Sachs, and Evercore are the joint book-running managers. The securities are offered under an automatically effective shelf registration statement filed with the SEC. This move aims to bolster Apellis's ability to develop innovative therapies targeting serious diseases.

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Apellis Pharmaceuticals has initiated an underwritten public offering of $300 million in its common stock, with the possibility of a 15% over-allotment option for underwriters. The offering is managed by J.P. Morgan, Goldman Sachs, and Evercore, and will occur under an automatically effective shelf registration filed with the SEC on February 22, 2023. The final terms will be disclosed in a prospectus supplement. Apellis, recognized for its advancements in complement medicine, aims to leverage the funds for its ongoing development of therapies targeting critical diseases.

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Apellis Pharmaceuticals announced its fourth quarter and full year 2022 financial results, highlighting the FDA approval of SYFOVRE as the first treatment for geographic atrophy due to age-related macular degeneration. The company generated $65.1 million in EMPAVELI U.S. net product revenues for 2022. R&D expenses decreased to $387.2 million, attributed to completed trials and collaborations. However, general and administrative expenses rose to $277.2 million. Apellis reported a net loss of $652.2 million for 2022. The company anticipates launching SYFOVRE in the U.S. by March 2023 and continues to pursue further approvals internationally.

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Apellis Pharmaceuticals has announced FDA approval for SYFOVRE™ (pegcetacoplan injection), the first treatment for geographic atrophy (GA)12,000 injections over 24 months. SYFOVRE is expected to be available by early March through specialty distributors. A marketing application is also under review in Europe, with a decision expected in early 2024.

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Apellis Pharmaceuticals (Nasdaq: APLS) announced the grant of equity awards to 8 new employees, effective February 1, 2023. These equity inducement awards were granted outside the 2017 Stock Incentive Plan, under the terms of the 2022 Inducement Stock Incentive Plan. The new hires received options for 18,435 restricted stock units (RSUs), which will vest over four years, contingent upon their continued employment. This initiative aims to attract talent and support the company's growth in the biopharmaceutical sector, focusing on developing therapies for rare, retinal, and neurological diseases.

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Apellis Pharmaceuticals (APLS) announced the appointment of Caroline Baumal, M.D., as the new chief medical officer, replacing Federico Grossi, M.D., Ph.D., who will assist during the transition until February 28, 2023. Dr. Baumal brings over 25 years of experience in retina research and patient care, crucial for the upcoming launch of pegcetacoplan for geographic atrophy (GA). The company is preparing for a PDUFA date next month, with pegcetacoplan showing promise in clinical trials as the first treatment for GA, a leading cause of blindness affecting millions.

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FAQ

What is the current stock price of Apellis Pharmaceuticals (APLS)?

The current stock price of Apellis Pharmaceuticals (APLS) is $30.76 as of January 23, 2025.

What is the market cap of Apellis Pharmaceuticals (APLS)?

The market cap of Apellis Pharmaceuticals (APLS) is approximately 3.8B.

What does Apellis Pharmaceuticals, Inc. specialize in?

Apellis specializes in the discovery, development, and commercialization of novel therapeutic compounds aimed at treating diseases with high unmet medical needs through the inhibition of the complement system.

What are Apellis's primary products?

Apellis's primary products are SYFOVRE® (pegcetacoplan injection) for geographic atrophy and EMPAVELI® (pegcetacoplan) for paroxysmal nocturnal hemoglobinuria (PNH).

How did Apellis perform financially in 2023?

In 2023, Apellis generated $397 million in revenue, with significant contributions from SYFOVRE and EMPAVELI.

What is SYFOVRE® approved for?

SYFOVRE® is approved for the treatment of geographic atrophy (GA), a leading cause of blindness related to age-related macular degeneration.

What is EMPAVELI® approved for?

EMPAVELI® is approved for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) in the United States, European Union, and other countries globally.

What recent clinical data has Apellis presented?

Apellis recently presented positive data from its Phase 2 NOBLE study for systemic pegcetacoplan in treating C3 glomerulopathy (C3G) and primary immune complex membranoproliferative glomerulonephritis (IC-MPGN) at the European Renal Association Congress.

What is the latest financial development for Apellis?

Apellis recently closed a $375 million funding deal with Sixth Street to buy out existing SFJ Pharmaceuticals development liabilities, significantly improving its liquidity profile.

What are Apellis's expectations for 2024?

In 2024, Apellis anticipates regulatory developments from EMA and expects topline data from the Phase 3 VALIANT study for systemic pegcetacoplan in mid-2024.

Who is Apellis collaborating with for systemic pegcetacoplan?

Apellis is collaborating with Sobi for the global co-development and commercialization of systemic pegcetacoplan.

How is Apellis combining science and patient care?

Apellis combines bold scientific endeavors with compassionate patient care, striving to bring life-changing therapies to patients with serious diseases.
Apellis Pharmaceuticals, Inc.

Nasdaq:APLS

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3.78B
105.12M
13.94%
98.84%
16.09%
Biotechnology
Pharmaceutical Preparations
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