APPILI THERAPEUTICS INC - APLIF STOCK NEWS

Appili Therapeutics Inc. (TSX: APLI; OTCQX: APLIF) has completed patient enrollment in the viral shedding sub-study of its Phase 3 PRESECO trial for the antiviral drug Avigan®/Reeqonus™ (favipiravir) aimed at treating COVID-19. Over 550 patients are enrolled to assess the drug's efficacy against emerging variants, including Delta. The sub-study's results will be released alongside PRESECO's top-line results. The study, conducted in the U.S., Brazil, and Mexico, targets adults with mild-to-moderate COVID-19 symptoms.

Appili Therapeutics announced the results of its annual general meeting held on September 7, 2021, highlighting shareholder approval of all resolutions. Josef Vejvoda has been elected to the Board of Directors, bringing over 25 years of capital markets experience. Voting results indicate strong support for board members, including Ian Mortimer and Brian Bloom, with percentages of votes for exceeding 99%. Additionally, PricewaterhouseCoopers was reappointed as the independent auditor. Appili focuses on developing novel therapies for infectious diseases, including ongoing trials for the antiviral Avigan/Reeqonus.

Appili Therapeutics Inc. (TSX:APLI; OTCQX: APLIF) reported its financial results for Q1 2022, ending June 30, 2021. The company incurred a net loss of $7.4 million ($0.12 per share), up from $2.6 million ($0.05 per share) in Q1 2021, largely due to increased R&D expenses. Operationally, it completed an interim analysis for the Phase 3 PRESECO trial of Avigan®/Reeqonus™ for COVID-19, receiving a recommendation to continue. The trial has expanded into Latin America, and the company secured $3.5 million in funding for its pipeline.

Appili Therapeutics (TSX: APLI; OTCQX: APLIF) reported its fiscal year results for 2021, showing a net loss of $14.3 million, up from $5.4 million in 2020. Research and development expenses rose by $8.1 million. The company has $16.1 million in cash and working capital of $13.6 million. Appili is encouraged by the independent monitoring board's recommendation to continue its Phase 3 PRESECO trial for Avigan/Reeqonus, targeting COVID-19. The company aims to advance its pipeline, including a $6.3 million grant for its ATI-1701 vaccine program.

Appili Therapeutics (OTCQX: APLIF) expands its Phase 3 PRESECO clinical trial of Avigan®/Reeqonus™ (favipiravir) for COVID-19 by adding clinical research sites in Mexico and Brazil. This move aims to expedite enrollment and trials completion, with top-line data expected by Q3 2021. The study focuses on a potential home treatment for mild-to-moderate COVID-19 patients. An independent Data and Safety Monitoring Board has recommended proceeding without modifications. The CONTROL trial is ended to prioritize PRESECO, and a future Phase 3 PEPCO study is planned for post-exposure prophylaxis.

Appili Therapeutics (APLIF) announced that the independent Data and Safety Monitoring Board (DSMB) has endorsed the continuation of its Phase 3 PRESECO trial for Avigan/Reeqonus (favipiravir) without modifications. This trial is aimed at evaluating the drug as a potential treatment for mild-to-moderate COVID-19 patients. With approximately 600 subjects involved, Appili expects to report top-line results in Q3 2021. The drug has a well-established safety profile and is part of a consortium aimed at global development for COVID-19 treatment.

Appili Therapeutics (OTCQX:APLIF) announces that CEO Dr. Armand Balboni will present at the Bloom Burton & Co. Healthcare Investor Conference on April 21, 2021, at 10:00 AM ET. The conference is fully virtual, and Appili will conduct one-to-one meetings with attendees. A live webcast of the presentation will be available on the Company’s website, with a replay accessible afterward. Appili focuses on developing anti-infective drug candidates to combat urgent infections worldwide.

Appili Therapeutics (TSX: APLI; OTCQX: APLIF) will present at the Inaugural Emerging Growth Virtual Conference from March 17-19. CEO Dr. Armand Balboni will partake in a Fireside Chat on March 19 at 4:30 PM ET. The presentation is scheduled for March 19 at 2:30 PM ET, with opportunities for one-to-one meetings throughout the conference. Interested investors can register HERE. A replay will be available on Appili’s website after the event.

Appili Therapeutics (TSX: APLI; OTCQX: APLIF) announced a webinar series focusing on infectious diseases, featuring notable experts like Dr. Scott Gottlieb and Dr. Syra Madad. The first event, scheduled for March 3 at 1:00 p.m. ET, will discuss pandemic response strategies and future infectious outbreaks. This initiative aims to enhance understanding and investment in treatments and public health policies. The company continues to support late-stage clinical trials for its antiviral candidate, highlighting its commitment to addressing urgent healthcare needs.