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Armata Pharmaceuticals has completed its Phase 1b/2a SWARM-P.a. clinical trial assessing inhaled AP-PA02 for cystic fibrosis patients with chronic pulmonary Pseudomonas aeruginosa infection. This milestone was noted by the company's executives, highlighting its implications for further phage therapy research. The study aims to evaluate safety, tolerability, and dosing paradigms necessary to meet microbiological endpoints, with topline data expected in Q1 2023. Armata previously received significant funding from the Cystic Fibrosis Foundation to support the development of this candidate.
Armata Pharmaceuticals (NYSE American: ARMP) will participate in the H.C. Wainwright 1st Annual Investor Conference on Bacteriophage, scheduled for November 30, 2022, from 10:00-10:30 AM EST. This conference will be held virtually, focusing on the company's advancements in bacteriophage therapeutics aimed at treating antibiotic-resistant infections. Armata is developing a diverse pipeline of phage candidates, particularly for Pseudomonas aeruginosa and Staphylococcus aureus, and collaborates with Merck on synthetic phage candidates.
Armata Pharmaceuticals (NYSE American: ARMP) announced enhancements to its lead bacteriophage product candidate, AP-PA02, increasing its potency and coverage against Pseudomonas aeruginosa strains in cystic fibrosis and non-cystic fibrosis bronchiectasis patients. The new formulation introduces two additional phage genera, achieving over 90% coverage of tested isolates. Armata plans to enter a Phase 2 trial for non-cystic fibrosis bronchiectasis in 2022. The company is also developing a distinct phage cocktail for pneumonia. These advancements align with Armata's strategy to improve bacteriophage therapy effectiveness.
Armata Pharmaceuticals (NYSE American: ARMP) announced significant progress in its phage therapeutic development programs. The FDA has cleared its IND for the Phase 1b/2a trial of AP-SA02 targeting Staphylococcus aureus bacteremia, expected to start by year-end. Additionally, a $2 million milestone under the CF Foundation's Therapeutics Development Award has been achieved, raising the total to $3.75 million. The company is focused on combating drug-resistant bacterial infections with support from the Cystic Fibrosis Foundation and U.S. Department of Defense.
Armata Pharmaceuticals announced that its Vice President of Clinical Development, Mina Pastagia, will present at the 2021 World Antimicrobial Resistance Congress in Washington D.C. on November 8. The presentation, titled A genomics-based approach for developing phage therapeutics targeting respiratory infections, will take place during the Innovation Showcase session at 2:30 pm ET.
This congress, now in its seventh year, will draw over 400 attendees and feature more than 150 speakers, focusing on antimicrobial resistance.
Armata Pharmaceuticals (NYSE American: ARMP) announced receiving a $3.0 million equity investment from the Cystic Fibrosis Foundation, with an additional $4.0 million from Innoviva, a significant shareholder. This investment will support Armata's lead clinical candidate, AP-PA02, currently in a Phase 1b/2a trial for chronic Pseudomonas aeruginosa infections in cystic fibrosis patients. This follows a prior $5.0 million Therapeutics Development Award from the Foundation in March 2020, emphasizing the urgent need for new therapies against difficult bacterial infections.
Armata Pharmaceuticals (NYSE American: ARMP), a biotechnology firm focused on bacteriophage therapeutics for antibiotic-resistant infections, will present at the Ladenburg Thalmann 2021 Healthcare Conference on July 13, 2021, at 4:00 PM ET. The event will feature one-on-one investor meetings and further details about Armata's innovative pipeline targeting pathogens such as Pseudomonas aeruginosa and Staphylococcus aureus. Interested parties can access the presentation through a provided webcast link.
Armata Pharmaceuticals (NYSE American: ARMP) announced a securities purchase agreement with Innoviva (Nasdaq: INVA), securing approximately $20 million in gross proceeds. The funds will support Armata's bacteriophage development programs, including the FDA-cleared SWARM-P.a. study for AP-PA02 targeting Pseudomonas aeruginosa infections. The agreement includes the purchase of 6.2 million shares at $3.25 each and warrants, scheduled in two tranches. Armata aims to achieve significant clinical milestones in 2021 and 2022, advancing its pipeline for combatting antibiotic-resistant infections.
Armata Pharmaceuticals announced the election of Robin C. Kramer to its Board of Directors on December 8, 2020. Currently serving as the VP and Chief Accounting Officer at Biogen, Kramer's extensive financial leadership experience is expected to bolster Armata's strategic direction. Directors H. Stewart Parker and Jeremy Curnock Cook did not seek re-election. CEO Todd R. Patrick expressed confidence in the enhanced board leadership during a critical phase of the company’s clinical development initiatives, focusing on solutions for antibiotic-resistant infections.
