Welcome to our dedicated page for AN2 Therapeutics news (Ticker: ANTX), a resource for investors and traders seeking the latest updates and insights on AN2 Therapeutics stock.
AN2 Therapeutics, Inc. (ANTX) is a clinical-stage biopharmaceutical company developing innovative treatments for serious infectious diseases. This news hub provides investors and stakeholders with timely updates on ANTX's progress in addressing conditions like non-tuberculous mycobacterial (NTM) lung disease through its investigational therapies.
Access authoritative information on clinical trial milestones, regulatory developments, and strategic partnerships. Our curated collection features official press releases and verified news about ANTX's drug pipeline, research advancements, and corporate announcements.
Key updates include progress on ANTX's lead oral therapeutic candidate, financial reporting disclosures, and collaborations advancing infectious disease treatment. Bookmark this page to stay informed about critical developments in ANTX's mission to transform patient outcomes through targeted biomedical innovation.
AN2 Therapeutics (ANTX) reported its Q4 and full year 2024 financial results, highlighting key pipeline developments. The company expects Phase 3 topline data for epetraborole in treatment-refractory MAC lung disease in Q2 2025. A Phase 1 study for AN2-502998 in Chagas disease is planned for mid-2025, while melioidosis trial data is expected in Q2 2025.
Financial highlights include cash position of $88.6 million as of December 31, 2024, expected to fund operations through 2027. Full-year 2024 R&D expenses were $40.5 million, down from $54.9 million in 2023. The company reported a net loss of $51.3 million for 2024, improved from $64.7 million in 2023.
The company amended its statistical analysis plan, selecting QOL-B respiratory domain as the primary efficacy endpoint for the Phase 3 epetraborole trial. Additionally, ANTX is advancing its boron chemistry platform with first oncology candidates expected in 2H25.
AN2 Therapeutics (Nasdaq: ANTX), a biopharmaceutical company specializing in boron chemistry platform-derived small molecule therapeutics, has announced its participation in the upcoming Leerink Partners Global Healthcare Conference.
Eric Easom, who serves as Co-Founder, Chairman, President and CEO, will deliver a corporate overview on March 12, 2025, at 2:20 pm ET. The management team will also be available for one-on-one meetings during the conference.
Investors and interested parties can access the presentation webcast through the Investors section of AN2 Therapeutics' website. The replay will remain available for a minimum of 30 days after the presentation.
AN2 Therapeutics (NASDAQ: ANTX) has announced a strategic update for its Phase 3 EBO-301 trial in treatment-refractory MAC lung disease. The company has submitted an amended statistical analysis plan to the FDA, selecting the Quality of Life – Bronchiectasis (QOL-B) respiratory domain patient reported outcome as the primary efficacy endpoint.
In the Phase 2 study, epetraborole showed nominal statistical superiority versus placebo, with a difference in least squares mean change from baseline of 6.90 (p=0.0365). The company plans to unblind Phase 3 data in Q2 2025, which includes 97 completed subjects. If Phase 3 data confirms Phase 2 findings, AN2 will discuss potential registrational pathways with the FDA for this highly refractory population.
This approach aligns with FDA's 2023 Guidance for Industry on NTM drug development and follows the precedent of Insmed's confirmatory Arikayce study in treatment-naïve MAC patients.
AN2 Therapeutics (Nasdaq: ANTX), a biopharmaceutical company specializing in boron chemistry platform-derived small molecule therapeutics, has announced its participation in two major investor conferences in March 2025.
At the TD Cowen 45th Annual Health Care Conference, Co-Founder, Chairman, President and CEO Eric Easom will deliver a corporate overview on March 3, 2025, at 2:30 pm ET. The management team will also be available for one-on-one meetings.
The company will also attend the Leerink Partners Global Healthcare Conference on March 12, 2025, where management will conduct one-on-one meetings. The TD Cowen conference presentation will be webcasted and accessible through AN2 Therapeutics' website, with a replay available for at least 30 days post-presentation.
AN2 Therapeutics (Nasdaq: ANTX), a biopharmaceutical company specializing in boron chemistry-based small molecule therapeutics, has announced its participation in the upcoming Oppenheimer 35th Annual Healthcare Life Sciences Conference.
Eric Easom, who serves as Co-Founder, Chairman, President and CEO, will deliver a corporate overview at the virtual event on Wednesday, February 12, 2025, at 3:20 PM ET. Interested parties can access the presentation through a webcast available on the Investors section of AN2 Therapeutics' website. The presentation recording will remain accessible for a minimum of 30 days after the event.
AN2 Therapeutics (Nasdaq: ANTX), a biopharmaceutical company specializing in boron chemistry-based small molecule therapeutics, has announced its participation in two major investor conferences this December. The company will present at the 7th Annual Evercore HealthCONx Conference (December 3-5, 2024), where CEO Eric Easom will deliver a corporate overview on December 4. Additionally, management will attend Oppenheimer's Movers in Rare Disease Summit on December 12, 2024, for one-on-one meetings.
The Evercore presentation will be available via webcast on AN2 Therapeutics' website, with a replay accessible for 30 days afterward.
AN2 Therapeutics (ANTX) reported Q3 2024 results and provided updates on its epetraborole program. The company's epetraborole-treated patients showed statistically significant clinical improvements in QOL-B respiratory domain and MACrO2 measures for treatment-refractory MAC lung disease. Financial highlights include cash position of $93.4M, expected to fund operations through 2027, and a 50% reduction in expenditures through restructuring. Q3 net loss was $12.7M compared to $16.7M in the same period 2023. The company plans to meet with FDA to discuss potential reinitiation of Phase 3 clinical study while advancing its boron chemistry pipeline in areas including Chagas disease, melioidosis, and oncology.
AN2 Therapeutics, Inc. (Nasdaq: ANTX) has received a second-year continuation of a research grant from the Bill & Melinda Gates Foundation to discover novel, boron-containing small molecules for the treatment of tuberculosis (TB) and malaria. The grant supports the discovery of novel inhibitors of aminoacyl-tRNA synthetases using AN2's proprietary boron chemistry platform.
The company aims to combat drug resistance and shorten treatment duration for these infectious diseases, which together cause nearly 2 million deaths per year worldwide. The program focuses on leucyl-tRNA synthetase, a validated human target in Mycobacteria and other bacteria and fungi, with potential applications in TB and nontuberculous Mycobacteria lung disease.
This research builds on AN2's scientific accomplishments in discovering novel leucyl-tRNA synthetase inhibitors, including epetraborole, tavaborole, and ganfeborole.
AN2 Therapeutics (Nasdaq: ANTX), a biopharmaceutical company specializing in novel small molecule therapeutics derived from boron chemistry, has announced its participation in the H.C. Wainwright 26th Annual Global Investment Conference. Eric Easom, the company's Co-Founder, Chairman, President, and CEO, will deliver a corporate overview on Tuesday, September 10 at 9:30am ET.
Investors and interested parties can access a webcast of the presentation through the Investors section of AN2 Therapeutics' website. The company will also provide an archived replay of the presentation, available for at least 30 days following the event. This conference appearance offers an opportunity for AN2 Therapeutics to showcase its progress and strategy in developing innovative therapeutics based on its proprietary boron chemistry platform.
AN2 Therapeutics (Nasdaq: ANTX) has adopted a duration stockholder rights plan set to expire on August 15, 2025. This decision comes after the company discovered a rapid accumulation of 19.3% of its common stock by BML Investment Partners, L.P. The plan aims to ensure fair treatment of all stockholders and protect against coercive tactics aimed at gaining control without paying a full premium.
Key points of the rights plan include:
- Distribution of one preferred stock purchase right per common stock share to stockholders of record on August 29, 2024
- Exercise price of $6.50 per right under certain circumstances
- Board's ability to redeem rights at $0.01 per right before 20% ownership threshold is reached
- Provisions for stockholders to purchase additional shares at a discount if a person or group acquires 20% or more of common stock
