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Alto Neuroscience Inc. - ANRO STOCK NEWS

Welcome to our dedicated page for Alto Neuroscience news (Ticker: ANRO), a resource for investors and traders seeking the latest updates and insights on Alto Neuroscience stock.

Alto Neuroscience Inc. (NYSE: ANRO) is a clinical-stage biopharmaceutical company dedicated to redefining psychiatry by leveraging neurobiology to develop personalized and highly effective treatment options. The company's innovative Precision Psychiatry Platform™ measures brain biomarkers by analyzing EEG activity, neurocognitive assessments, wearable data, and other factors to identify which patients are more likely to respond to their product candidates.

Alto's clinical-stage pipeline includes several promising drug candidates targeting various neuropsychiatric disorders such as depression, PTSD, schizophrenia, and cognitive impairments. Some of the key assets in their pipeline include ALTO-100, ALTO-202, ALTO-101, and ALTO-300, initially focusing on depressive disorders and schizophrenia populations as identified by brain-based biomarkers.

In recent news, Alto Neuroscience announced the pricing and closing of its upsized initial public offering (IPO) of over 9 million shares of common stock, generating approximately $147.9 million in gross proceeds. The company's stock began trading on the New York Stock Exchange on February 2, 2024, under the ticker symbol 'ANRO'.

Alto’s lead product candidates, ALTO-100 and ALTO-300, have shown positive Phase 2a results in major depressive disorder (MDD) trials. Enrollment is on track for Phase 2b studies, with expected data readouts in the second half of 2024 for ALTO-100 and the first half of 2025 for ALTO-300. Additionally, ALTO-101, a novel PDE4 inhibitor, has demonstrated favorable results in Phase 1, with plans to initiate a proof-of-concept study for cognitive impairment associated with schizophrenia (CIAS) in 2024.

With a robust cash position of approximately $206 million as of March 31, 2024, Alto Neuroscience is well-positioned to support its planned operations into 2027. The company is committed to advancing its mission of providing personalized treatment options for patients with neuropsychiatric conditions and delivering value to shareholders.

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Alto Neuroscience (NYSE: ANRO) announced its participation in the Jefferies Global Healthcare Conference in New York from June 5-6, 2024. Founder and CEO Amit Etkin, M.D., Ph.D., will engage in a fireside chat on June 6, 2024, at 2:30 p.m. ET. Additionally, the company's management will hold one-on-one meetings with investors. A live webcast of the discussion will be available on Alto's investor relations webpage, with a replay accessible afterward.

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Alto Neuroscience (NYSE: ANRO) has appointed Michael Hanley as its new Chief Operating Officer (COO). Hanley brings over 25 years of expertise in the life sciences industry, particularly in neuropsychiatric conditions like major depressive disorder and schizophrenia. His role will involve new product planning, portfolio strategy, and cross-functional leadership to enhance Alto's clinical-stage programs and biomarker platform. Hanley's extensive background includes leadership positions at Aeglea BioTherapeutics and Horizon Therapeutics. He holds a Bachelor of Business Administration from the University of Notre Dame and an MBA from Kellogg School of Management.

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Alto Neuroscience (NYSE: ANRO) announced its Q1 2024 financial results and recent business updates. The company initiated a Phase 2 study of ALTO-203 for MDD and anhedonia, and reported positive Phase 1 data for the transdermal formulation of ALTO-101, showing improved drug exposure and tolerability. Patient enrollment for ALTO-100 and ALTO-300 Phase 2b MDD studies is progressing well. The company has a strong cash position of approximately $206 million, expected to support operations into 2027.

Alto's ongoing studies include ALTO-100 and ALTO-300, both targeting MDD, and ALTO-101 for CIAS. The company also announced the initiation of a Phase 2 proof-of-concept study for ALTO-203 in patients with MDD and high levels of anhedonia. Financial highlights include a net loss of $13.4 million, an increase in R&D expenses to $10 million, and higher G&A expenses reaching $4.4 million. Alto completed an upsized IPO in February 2024, netting $133 million in proceeds.

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Alto Neuroscience, Inc. ('Alto') (ANRO) announced upcoming data presentations at the Society of Biological Psychiatry and American Society of Clinical Psychopharmacology Annual Meetings, showcasing its precision psychiatry pipeline. The company highlighted neurobiological markers linked to cognitive impairment in schizophrenia and the development of novel compounds for depression and schizophrenia. The ALTO-100 study identified memory-based cognitive markers predicting antidepressant response, while ALTO-101 showed significant effects on electrophysiological measures relevant to cognitive processing. ALTO-300 demonstrated EEG-based cognitive markers predicting greater response. The presentations aim to contribute to the scientific community and further develop treatment options for patients.

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Alto Neuroscience, Inc. (NYSE: ANRO) announces positive Phase 1 results for ALTO-101, a novel PDE4 inhibitor developed for cognitive impairment associated with schizophrenia. The study showed improved pharmacokinetics and tolerability with a transdermal delivery system, reducing adverse events. The company plans a proof-of-concept study for CIAS in 2024, with topline data expected in 2025.
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Alto Neuroscience, Inc. (NYSE: ANRO) initiates Phase 2 study for ALTO-203 in major depressive disorder patients with anhedonia, showing positive emotional and cognitive effects in Phase 1 trials. The study aims to evaluate its antidepressant potential.
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Alto Neuroscience, Inc. (ANRO) reported positive Phase 2a results for ALTO-100 and ALTO-300, highlighting response prediction using their Precision Psychiatry Platform™. The company is on track with patient enrollment for Phase 2b MDD studies. They successfully completed an oversubscribed IPO, with a cash position of $210 million as of February 29, 2024.
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Alto Neuroscience, Inc. (NYSE: ANRO) appoints Dr. Maha Radhakrishnan, an experienced industry executive, to its board of directors. Dr. Radhakrishnan brings decades of expertise in product development and global medical strategy from leading biotechnology and pharmaceutical companies. Her appointment signifies Alto's commitment to advancing precision psychiatry and personalized patient care.
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Alto Neuroscience, Inc. (ANRO) announced its participation in upcoming investor conferences, including Jefferies Biotech on the Bay Summit, UBS Virtual CNS Day, and Stifel 2024 Virtual CNS Days. Dr. Amit Etkin, the CEO, will be engaging in one-on-one meetings and fireside chats during the conferences, providing investors with valuable insights.
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Alto Neuroscience, Inc. (ANRO) CEO Amit Etkin to present at TD Cowen 44th Annual Healthcare Conference. The presentation will be available via live webcast and replay for 90 days.
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FAQ

What is the current stock price of Alto Neuroscience (ANRO)?

The current stock price of Alto Neuroscience (ANRO) is $4.52 as of November 15, 2024.

What is the market cap of Alto Neuroscience (ANRO)?

The market cap of Alto Neuroscience (ANRO) is approximately 119.2M.

What is the mission of Alto Neuroscience?

Alto Neuroscience aims to redefine psychiatry by leveraging neurobiology to develop personalized and highly effective treatment options.

What are some key products in Alto’s pipeline?

Key products include ALTO-100, ALTO-202, ALTO-101, and ALTO-300, focused on treating depressive disorders and schizophrenia.

What recent financial achievements has Alto Neuroscience announced?

Alto recently closed its upsized initial public offering, raising approximately $147.9 million in gross proceeds.

When can we expect data readouts for ALTO-100 and ALTO-300?

Topline data for ALTO-100 is expected in the second half of 2024, and for ALTO-300 in the first half of 2025.

What is ALTO-101 and its current development status?

ALTO-101 is a novel PDE4 inhibitor in Phase 1 development for cognitive impairment associated with schizophrenia, with a proof-of-concept study planned for 2024.

How does Alto's Precision Psychiatry Platform™ work?

The platform measures brain biomarkers by analyzing EEG activity, neurocognitive assessments, wearable data, and other factors to identify which patients are likely to respond to their treatments.

What is Alto’s financial condition as of early 2024?

As of March 31, 2024, Alto Neuroscience had a strong cash position of approximately $206 million, supporting operations into 2027.

Which institutions were involved in Alto’s initial public offering?

Jefferies, TD Cowen, Stifel, and William Blair were joint book-running managers, with Baird as the lead manager.

What is the focus of ALTO-300’s development?

ALTO-300 is being developed as an adjunctive treatment for major depressive disorder, particularly for patients who haven't responded well to standard antidepressants.

What significant appointments were made to Alto’s board in early 2024?

Maha Radhakrishnan, M.D., and Husseini Manji, M.D., Ph.D., both industry veterans, were appointed to the company's board of directors.

Alto Neuroscience Inc.

NYSE:ANRO

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119.16M
26.96M
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77.01%
19.85%
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