Angle PLC Announces Result of 2020 Annual General Meeting
ANGLE plc (OTCQX:ANPCY) successfully held its Annual General Meeting on August 27, 2020, where all proposed resolutions were passed. As a leader in liquid biopsy technology, ANGLE's Parsortix® system captures circulating tumor cells for further analysis, aiming for FDA clearance amidst ongoing clinical studies. The company continues to refine its ovarian cancer triage test, demonstrating impressive accuracy rates. Additionally, ANGLE maintains partnerships with notable corporations and cancer centers to advance its innovative solutions in cancer diagnostics.
- All resolutions passed at the Annual General Meeting.
- Successfully advancing clinical studies with favorable accuracy metrics (ROC-AUC of 95.1%).
- Partnerships with leading companies like Abbott, Philips, and QIAGEN to strengthen market position.
- None.
GUILDFORD, SURREY / ACCESSWIRE / August 27, 2020 / ANGLE plc (AIM:AGL)(OTCQX:ANPCY), a world-leading liquid biopsy company, announces that at the Annual General Meeting of the Company held earlier today, all resolutions were duly passed.
For further information ANGLE:
ANGLE plc | +44 (0) 1483 343434 |
finnCap Ltd (NOMAD and Joint Broker) | +44 (0)20 7220 0500 |
WG Partners (Joint Broker) | +44 (0) 203 705 9330 |
FTI Consulting | +44 (0) 203 727 1000 |
About ANGLE plc www.angleplc.com
ANGLE is a world leading liquid biopsy company with sample-to-answer solutions. ANGLE's proven patent protected platforms include a circulating tumor cell (CTC) harvesting technology and a downstream analysis system for cost effective, highly multiplexed analysis of nucleic acids and proteins.
ANGLE's cell separation technology is called the Parsortix® system, and it enables a liquid biopsy (a simple blood test) to be used to provide the cells of interest to the user in a format suitable for multiple types of downstream analyses. The system is based on a microfluidic device that captures cells based on a combination of their size and compressibility. The system is epitope independent and can capture all types of CTCs as well as CTC clusters in a viable form (alive). CTCs enable the complete picture of a cancer to be seen as being a complete cell they allow DNA, RNA and protein analysis and the live cells harvested can be cultured. The Parsortix technology is the subject of 24 granted patents in Europe, the United States, China, Australia, Canada, India, Japan and Mexico with three extensive families of patents are being progressed worldwide. The Parsortix system has a CE Mark in Europe for the indicated use and FDA clearance is in process for the United States with a 400 subject clinical study and associated analytical studies in metastatic breast cancer. ANGLE is seeking to be the first ever FDA cleared CTC harvesting system and only the third ever FDA cleared liquid biopsy test. ANGLE has already undertaken two separate 200 subject clinical studies under a program designed to develop an ovarian cancer pelvic mass triage test, with the results showing best in class accuracy (ROC-AUC) of
ANGLE's technology for the multiplex evaluation of proteins and nucleic acids of all types is called the HyCEADTM Ziplex® platform and is based on a patented flow through array technology. It provides for low cost, highly multiplexed, rapid and sensitive capture of targets from a wide variety of sample types. A proprietary chemistry approach (the HyCEAD method) allows for the capture and amplification of over 100 biomarkers simultaneously in a single reaction. The HyCEAD Ziplex system is extremely sensitive and is ideal for measuring gene expression and other markers directly from Parsortix harvests and was used in the ovarian cancer pelvic mass triage test to achieve best in class accuracy (ROC-AUC) of
ANGLE's proprietary technologies can be combined to provide automated, sample-to-answer results in both centralised laboratory and point-of-use cartridge formats.
ANGLE has established formal collaborations with world-class cancer centres and major corporates such as Abbott, Philips and QIAGEN, and works closely with leading CTC translational research customers. These Key Opinion Leaders (KOLs) are working to identify applications with medical utility (clear benefit to patients), and to secure clinical data that demonstrates that utility in patient studies. The body of evidence as to the benefits of the Parsortix system is growing rapidly from our own clinical studies in metastatic breast cancer and ovarian cancer and also from KOLs with 35 peer-reviewed publications and numerous publicly available posters, available on our website.
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SOURCE: ANGLE plc
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