STOCK TITAN

Aileron Therapeutics Inc - ALRN STOCK NEWS

Welcome to our dedicated page for Aileron Therapeutics news (Ticker: ALRN), a resource for investors and traders seeking the latest updates and insights on Aileron Therapeutics stock.

Aileron Therapeutics Inc. (ALRN) is a clinical-stage biopharmaceutical company advancing novel therapies targeting p53 tumor suppression in oncology and orphan pulmonary diseases. This page serves as the definitive source for verified corporate announcements, clinical trial updates, and regulatory developments.

Investors and researchers will find timely updates on ALRN-6924's dual mdmx/mdm2 inhibition mechanism, pulmonary fibrosis candidate LTI-03, and other pipeline advancements. Our curated news collection includes earnings reports, partnership announcements, and scientific presentations - all essential for understanding the company's progress in stapled peptide therapeutics.

Content spans multiple categories including clinical trial milestones, FDA designations, financial disclosures, and peer-reviewed research publications. Bookmark this page for structured access to ALRN's evolving therapeutic pipeline and strategic business developments.

Rhea-AI Summary

Aileron Therapeutics (NASDAQ: ALRN) reported its Q1 2024 financial results, highlighting positive data from Cohort 1 of its Phase 1b trial for LTI-03 in idiopathic pulmonary fibrosis (IPF) patients. The trial showed statistical significance in three out of eight biomarkers, with promising safety and tolerability. Topline results from Cohort 2 are expected in Q3 2024. The company raised approximately $20 million from a direct offering in May 2024, potentially adding another $20 million from warrant exercises. Cash reserves were $12 million as of March 31, 2024, expected to fund operations into H2 2025. R&D expenses rose to $3.5 million from $1.8 million YoY, primarily due to the acquisition of Lung. G&A expenses increased to $3.7 million from $2.2 million. Net loss for the quarter was $7.1 million, compared to $4.8 million in Q1 2023.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-1.28%
Tags
-
Rhea-AI Summary

Aileron Therapeutics, Inc. announced that its President and CEO will present at two upcoming investor conferences, sharing insights on their pipeline of medicines targeting orphan pulmonary and fibrosis indications. The conferences are Citizens JMP Life Sciences Conference on May 13, 2024, and H.C. Wainwright 2nd Annual BioConnect Investor Conference on May 20, 2024.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-6.58%
Tags
conferences
-
Rhea-AI Summary

Aileron Therapeutics, Inc. announced the closing of an underwritten registered direct offering of approximately $40 million, with $20 million in initial funding and potential additional proceeds of $20 million from warrants. The offering included 4,273,505 shares of common stock and warrants at a combined public offering price of $4.68 per share. The warrants, exercisable immediately, have an exercise price of $4.68 per share and expire in three years. Titan Partners Group served as the book-running manager for the offering.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
5.05%
Tags
Rhea-AI Summary

Aileron Therapeutics, Inc. announced the pricing of an underwritten registered direct offering to raise up to $40 million under Nasdaq rules. The offering includes 4,273,505 shares of common stock and warrants to purchase an equal number of shares. The offering is expected to generate approximately $20 million in gross proceeds, with the potential for an additional $20 million from warrant exercises. The warrants have an exercise price of $4.68 per share and will expire three years from the date of issuance. The offering is subject to customary closing conditions and is expected to close on or about May 3, 2024.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-8.57%
Tags
-
Rhea-AI Summary

Aileron Therapeutics, Inc. announced positive data from Cohort 1 of the Phase 1b clinical trial of LTI-03 in IPF. Low-dose LTI-03 showed reductions in profibrotic proteins, increased expression of biomarkers, and was well-tolerated. Positive trends were observed in seven out of eight biomarkers. Data from Cohort 2 is expected in Q3 2024.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-8.57%
Tags
-
Rhea-AI Summary
Aileron Therapeutics, Inc. reported its financial results for the fourth quarter and full year 2023, highlighting the successful completion of the merger with Lung Therapeutics. The company's lead product candidate, LTI-03, is expected to deliver topline results from a Phase 1b study in the third quarter of 2024. Aileron's cash runway is projected to support operations and key milestones through the fourth quarter of 2024.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-9.78%
Tags
Rhea-AI Summary
Aileron Therapeutics, Inc. appoints Brian Windsor, Ph.D., as the new CEO, succeeding Manuel Aivado, M.D., Ph.D. The company focuses on developing first-in-class medicines for orphan pulmonary and fibrosis diseases. Dr. Windsor's appointment follows the acquisition of Lung Therapeutics, Inc. The transition aims to advance Aileron's pipeline of therapies for life-threatening pulmonary conditions.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-5.41%
Tags
none
-
Rhea-AI Summary
Aileron Therapeutics, Inc. announces topline results from Phase 1b study of LTI-03, a novel Caveolin-1-related peptide for idiopathic pulmonary fibrosis. The company will host a virtual key opinion leader event to discuss the treatment landscape and significant unmet needs in IPF.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
0.21%
Tags
none
-
Rhea-AI Summary
Aileron Therapeutics, Inc. will host a virtual key opinion leader event to discuss LTI-03, a novel Caveolin-1-related peptide for the treatment of idiopathic pulmonary fibrosis. The event will feature a panel discussion with pulmonary care medicine experts and will focus on emerging therapies, including LTI-03. Aileron's pipeline of first-in-class medicines aims to address unmet medical needs in orphan pulmonary and fibrosis indications.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
13.44%
Tags
conferences
Rhea-AI Summary
Aileron Therapeutics, Inc. has acquired Lung Therapeutics, Inc., a biopharmaceutical company focused on developing therapies for orphan pulmonary and fibrosis indications. The acquisition includes multiple clinical-stage candidates, including LTI-03 for the treatment of idiopathic pulmonary fibrosis (IPF). Aileron also entered into a private placement to raise approximately $18 million to fund the ongoing Phase 1b clinical study of LTI-03 and for general corporate purposes.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-4.1%
Tags
Aileron Therapeutics Inc

Nasdaq:ALRN

ALRN Rankings

ALRN Stock Data

45.72M
21.63M
0.65%
28.47%
1.08%
Biotechnology
Pharmaceutical Preparations
Link
United States
AUSTIN