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Alnylam Pharmaceuticals, Inc. - ALNY STOCK NEWS

Welcome to our dedicated page for Alnylam Pharmaceuticals news (Ticker: ALNY), a resource for investors and traders seeking the latest updates and insights on Alnylam Pharmaceuticals stock.

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY) is at the forefront of RNA interference (RNAi) therapeutics, pioneering a transformative class of medicines aimed at treating and potentially curing a wide range of diseases. Founded in 2002 and based in Cambridge, MA, Alnylam has translated Nobel Prize-winning science into five commercial products: ONPATTRO (patisiran), AMVUTTRA (vutrisiran), GIVLAARI (givosiran), OXLUMO (lumasiran), and Leqvio (inclisiran), developed and commercialized in partnership with Novartis. These breakthrough therapeutics address conditions such as hATTR amyloidosis, acute hepatic porphyria, primary hyperoxaluria type 1, and hypercholesterolemia.

Alnylam is dedicated to expanding its pipeline with several investigational medicines in late-stage development, focusing on genetic medicines, cardio-metabolic diseases, hepatic infectious diseases, and CNS/ocular diseases. The company’s commitment to sustainable innovation is reflected in its robust product pipeline and strategic collaborations with industry leaders like Roche and Regeneron.

Financially, Alnylam reported robust growth in 2023 with $1.24 billion in global net product revenues, a reflection of its strong commercial execution across its therapeutic products. The company maintains a strong cash position, bolstered by upfront fees from research partnerships and milestone achievements.

Alnylam is also dedicated to corporate responsibility, with initiatives aimed at reducing greenhouse gas emissions, promoting diversity and inclusion in clinical trials, and expanding global health equity through its Alnylam Challengers program. The company’s environmental impact data is third-party verified, underscoring its commitment to transparency and sustainability.

Looking ahead, Alnylam aims to sustain its leadership in RNAi therapeutics with the anticipated release of topline results from the HELIOS-B Phase 3 study and the continued development of promising candidates like zilebesiran for hypertension and mivelsiran for Alzheimer’s disease. For more details on Alnylam’s people, science, and pipeline, visit www.alnylam.com.

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Alnylam Pharmaceuticals (Nasdaq: ALNY) will present an overview and participate in a Q&A session at the 41st Annual J.P. Morgan Healthcare Conference on January 9, 2023, at 9:45 am PT (12:45 pm ET) in San Francisco. The presentation will include an update on unaudited global net product revenues for Q4 and full year 2022. A live audio webcast will be available on their website, with a replay accessible within 48 hours. Alnylam is known for pioneering RNA interference therapeutics aimed at treating rare diseases.

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Alnylam Pharmaceuticals (ALNY) has submitted a Clinical Trial Authorization application to Health Canada to initiate a Phase 1/2 study of ALN-KHK, an investigational RNAi therapeutic for Type 2 diabetes mellitus (T2DM). The study is set to enroll healthy and obese patients in early 2023, with initial results expected by late 2023. ALN-KHK targets ketohexokinase to potentially improve glycemic control. With T2DM affecting over 450 million globally, the need for effective treatments remains critical. Alnylam aims to innovate in the RNAi therapeutic space, leveraging new technologies.

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Alnylam Pharmaceuticals hosted its R&D Day, outlining goals for 2023, including a potential label expansion and plans to report ten clinical datasets from its RNAi platform. The company aims for strong commercial execution across four brands and anticipates FDA approval for Patisiran to treat cardiomyopathy associated with ATTR amyloidosis in late 2023. Alnylam also plans to advance investigational therapies for various conditions including hypertension, Alzheimer's, and Type 2 diabetes. The webcast of the event is available online.

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Alnylam Pharmaceuticals has submitted a supplemental New Drug Application (sNDA) to the FDA for patisiran, an investigational RNAi therapeutic aimed at treating transthyretin-mediated (ATTR) amyloidosis with cardiomyopathy. This follows positive results from the Phase 3 APOLLO-B study, which demonstrated significant improvements in functional capacity and quality of life at 12 months. The study also showed an encouraging safety profile, with most adverse events being mild to moderate. Patisiran is already FDA approved for polyneuropathy of hereditary ATTR amyloidosis.

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Alnylam Pharmaceuticals has announced a virtual R&D Day scheduled for December 15, 2022, at 8:30 am ET, which will be webcast on the company's website. A replay will be available within 48 hours post-event. Alnylam, a leader in RNA interference therapeutics, aims to transform treatments for rare and common diseases. The company has developed several commercial products and has a robust pipeline of investigational medicines. To learn more, visit www.alnylam.com.

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Alnylam Pharmaceuticals (Nasdaq: ALNY) has announced its participation in multiple healthcare conferences. On November 16, 2022, the company will present at both the Jefferies London Healthcare Conference and Stifel 2022 Healthcare Conference at 2:05 pm GMT and 1:15 pm ET, respectively. Additionally, Alnylam will engage in the Evercore ISI HealthCONx Conference on November 29, and the Piper Sandler Healthcare Conference on November 30. A live audio webcast of these events will be available on Alnylam's website.

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Alnylam Pharmaceuticals reported Q3 2022 global net product revenues of $232 million, a 39% increase year-over-year. AMVUTTRA achieved $25 million in revenue, driving a 30% increase in U.S. TTR growth from Q2. Positive results were announced from the APOLLO-B Phase 3 study of patisiran, with an sNDA submission planned by year-end. The company reiterated its 2022 combined net product revenue guidance of $870-$930 million. Research and development expenses rose, while cash and equivalents were $2.27 billion as of September 30, down from $2.44 billion at the year's start.

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Alnylam Pharmaceuticals (NASDAQ: ALNY) will report its third-quarter financial results on October 27, 2022, before U.S. market opening. The management will hold a conference call on the same date at 8:30 am ET to discuss the results and future expectations. A live audio webcast will be available on the company's investor website. Alnylam continues to lead in RNA interference therapeutics, offering products like ONPATTRO and GIVLAARI, and has a robust pipeline with six late-stage candidates. The firm is committed to developing innovative medicines for rare diseases.

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FAQ

What is the current stock price of Alnylam Pharmaceuticals (ALNY)?

The current stock price of Alnylam Pharmaceuticals (ALNY) is $245.44 as of December 20, 2024.

What is the market cap of Alnylam Pharmaceuticals (ALNY)?

The market cap of Alnylam Pharmaceuticals (ALNY) is approximately 30.7B.

What is Alnylam Pharmaceuticals known for?

Alnylam Pharmaceuticals is known for pioneering RNA interference (RNAi) therapeutics, which are innovative medicines designed to silence disease-causing genes.

What products has Alnylam commercialized?

Alnylam has commercialized ONPATTRO (patisiran), AMVUTTRA (vutrisiran), GIVLAARI (givosiran), OXLUMO (lumasiran), and Leqvio (inclisiran).

What diseases do Alnylam’s products treat?

Alnylam’s products treat conditions like hATTR amyloidosis, acute hepatic porphyria, primary hyperoxaluria type 1, and hypercholesterolemia.

What are the recent financial achievements of Alnylam?

In 2023, Alnylam reported $1.24 billion in global net product revenues, reflecting strong commercial execution and growth.

Who are Alnylam’s key strategic partners?

Key strategic partners include Roche, Regeneron, and Novartis, with collaborations focusing on various clinical programs and commercial products.

What environmental initiatives has Alnylam undertaken?

Alnylam has disclosed multiyear data on greenhouse gas emissions, energy, water, and waste management, with third-party verification to ensure transparency and sustainability.

What is the Alnylam Challengers program?

The Alnylam Challengers program is a global health equity initiative that partners with social entrepreneurs and non-profit organizations to address health and economic inequalities.

What are some key pipeline developments for Alnylam?

Key pipeline developments include the HELIOS-B Phase 3 study for vutrisiran in ATTR amyloidosis, and early-stage developments for mivelsiran in Alzheimer’s disease.

Where is Alnylam Pharmaceuticals headquartered?

Alnylam Pharmaceuticals is headquartered in Cambridge, Massachusetts.

How can I learn more about Alnylam Pharmaceuticals?

For more information, visit their official website at www.alnylam.com.

Alnylam Pharmaceuticals, Inc.

Nasdaq:ALNY

ALNY Rankings

ALNY Stock Data

30.67B
128.18M
0.43%
98.2%
2.9%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
CAMBRIDGE