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Alnylam Pharmaceuticals, Inc. - ALNY STOCK NEWS

Welcome to our dedicated page for Alnylam Pharmaceuticals news (Ticker: ALNY), a resource for investors and traders seeking the latest updates and insights on Alnylam Pharmaceuticals stock.

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY) is at the forefront of RNA interference (RNAi) therapeutics, pioneering a transformative class of medicines aimed at treating and potentially curing a wide range of diseases. Founded in 2002 and based in Cambridge, MA, Alnylam has translated Nobel Prize-winning science into five commercial products: ONPATTRO (patisiran), AMVUTTRA (vutrisiran), GIVLAARI (givosiran), OXLUMO (lumasiran), and Leqvio (inclisiran), developed and commercialized in partnership with Novartis. These breakthrough therapeutics address conditions such as hATTR amyloidosis, acute hepatic porphyria, primary hyperoxaluria type 1, and hypercholesterolemia.

Alnylam is dedicated to expanding its pipeline with several investigational medicines in late-stage development, focusing on genetic medicines, cardio-metabolic diseases, hepatic infectious diseases, and CNS/ocular diseases. The company’s commitment to sustainable innovation is reflected in its robust product pipeline and strategic collaborations with industry leaders like Roche and Regeneron.

Financially, Alnylam reported robust growth in 2023 with $1.24 billion in global net product revenues, a reflection of its strong commercial execution across its therapeutic products. The company maintains a strong cash position, bolstered by upfront fees from research partnerships and milestone achievements.

Alnylam is also dedicated to corporate responsibility, with initiatives aimed at reducing greenhouse gas emissions, promoting diversity and inclusion in clinical trials, and expanding global health equity through its Alnylam Challengers program. The company’s environmental impact data is third-party verified, underscoring its commitment to transparency and sustainability.

Looking ahead, Alnylam aims to sustain its leadership in RNAi therapeutics with the anticipated release of topline results from the HELIOS-B Phase 3 study and the continued development of promising candidates like zilebesiran for hypertension and mivelsiran for Alzheimer’s disease. For more details on Alnylam’s people, science, and pipeline, visit www.alnylam.com.

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Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY) achieved full year 2023 preliminary global net product revenues of $1,241 million for ONPATTRO, AMVUTTRA, GIVLAARI, and OXLUMO, representing 39% annual growth. The company maintained a strong balance sheet with a year-end cash and investments balance of approximately $2.4 billion.
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Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY) will present a company overview and participate in a Q&A session at the 42nd Annual J.P. Morgan Healthcare Conference on January 8, 2024. The presentation will include an update on unaudited fourth quarter and full year 2023 global net product revenues.
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Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY) presents positive initial Phase 1 results for ALN-TTRsc04 and ALN-KHK, with rapid knockdown and robust target engagement. The company anticipates IND applications for nine or more programs by the end of 2025, showcasing its R&D progress and platform innovation, as well as its product and pipeline goals for 2024.
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Alnylam Pharmaceuticals, Inc. (ALNY) to Webcast Virtual R&D Day Event on December 13, 2023
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Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY) has been ranked as the #1 Top Place to Work in the 'Largest Employer' category by The Boston Globe for the third consecutive year. This recognition is based on an anonymous survey completed by 137,000 employees across 347 different companies in Massachusetts, focusing on workplace environment, company direction, execution, connection, management, work, pay and benefits, and engagement.
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ALNY - Alnylam Pharmaceuticals, Inc. - announced positive results from the KARDIA-1 Phase 2 study of zilebesiran, an investigational RNAi therapeutic targeting liver-expressed angiotensinogen (AGT) for hypertension treatment. The study achieved a 16.7 mmHg placebo-adjusted reduction in 24-hour mean systolic blood pressure at 3 months. Zilebesiran also demonstrated consistent and sustained reductions in systolic blood pressure up to 6 months, supporting quarterly or biannual dosing. The study showed encouraging safety and tolerability in adult patients with mild-to-moderate hypertension.
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Alnylam Pharmaceuticals, Inc. will present company overviews at three upcoming healthcare conferences in November 2023, providing live audio webcasts and replays on their website.
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Alnylam Pharmaceuticals, Inc. reported Q3 2023 global net product revenues of $313 million, a 35% YoY growth. They received a Complete Response Letter from the FDA for a supplemental new drug application for Patisiran. The company remains on track to report topline results from the HELIOS-B Phase 3 study in early 2024. They also reported positive topline results from the KARDIA-1 Phase 2 study of Zilebesiran. Alnylam updated their 2023 revenue guidance and reiterated their guidance for combined net product revenues.
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Alnylam Pharmaceuticals has been ranked third in Science magazine’s Top Employer Survey for 2023, marking the fifth year the company has been featured in the top three. The survey included over 6,800 professionals in the biotechnology and biopharmaceutical industries, who rated companies based on 24 characteristics. Alnylam's top attributes included treating employees with respect, social responsibility, and work culture values aligned with personal values.
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Alnylam Pharmaceuticals announced results from the APOLLO-B Phase 3 study of patisiran in patients with ATTR amyloidosis. The study showed that patisiran preserved functional capacity and health status compared to placebo at 12 months. Patisiran also demonstrated favorable effects on cardiac biomarkers and measures of cardiac structure and function. The results support the potential of RNAi therapeutics in treating ATTR amyloidosis.
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FAQ

What is the current stock price of Alnylam Pharmaceuticals (ALNY)?

The current stock price of Alnylam Pharmaceuticals (ALNY) is $245.44 as of December 20, 2024.

What is the market cap of Alnylam Pharmaceuticals (ALNY)?

The market cap of Alnylam Pharmaceuticals (ALNY) is approximately 30.7B.

What is Alnylam Pharmaceuticals known for?

Alnylam Pharmaceuticals is known for pioneering RNA interference (RNAi) therapeutics, which are innovative medicines designed to silence disease-causing genes.

What products has Alnylam commercialized?

Alnylam has commercialized ONPATTRO (patisiran), AMVUTTRA (vutrisiran), GIVLAARI (givosiran), OXLUMO (lumasiran), and Leqvio (inclisiran).

What diseases do Alnylam’s products treat?

Alnylam’s products treat conditions like hATTR amyloidosis, acute hepatic porphyria, primary hyperoxaluria type 1, and hypercholesterolemia.

What are the recent financial achievements of Alnylam?

In 2023, Alnylam reported $1.24 billion in global net product revenues, reflecting strong commercial execution and growth.

Who are Alnylam’s key strategic partners?

Key strategic partners include Roche, Regeneron, and Novartis, with collaborations focusing on various clinical programs and commercial products.

What environmental initiatives has Alnylam undertaken?

Alnylam has disclosed multiyear data on greenhouse gas emissions, energy, water, and waste management, with third-party verification to ensure transparency and sustainability.

What is the Alnylam Challengers program?

The Alnylam Challengers program is a global health equity initiative that partners with social entrepreneurs and non-profit organizations to address health and economic inequalities.

What are some key pipeline developments for Alnylam?

Key pipeline developments include the HELIOS-B Phase 3 study for vutrisiran in ATTR amyloidosis, and early-stage developments for mivelsiran in Alzheimer’s disease.

Where is Alnylam Pharmaceuticals headquartered?

Alnylam Pharmaceuticals is headquartered in Cambridge, Massachusetts.

How can I learn more about Alnylam Pharmaceuticals?

For more information, visit their official website at www.alnylam.com.

Alnylam Pharmaceuticals, Inc.

Nasdaq:ALNY

ALNY Rankings

ALNY Stock Data

30.67B
128.18M
0.43%
98.2%
2.9%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
CAMBRIDGE