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Aligos Therapeutics, Inc. - ALGS STOCK NEWS

Welcome to our dedicated page for Aligos Therapeutics news (Ticker: ALGS), a resource for investors and traders seeking the latest updates and insights on Aligos Therapeutics stock.

Aligos Therapeutics, Inc. (NASDAQ: ALGS) is a clinical-stage biopharmaceutical company headquartered in South San Francisco, California, and founded in 2018. The company is dedicated to developing novel therapeutics to address unmet medical needs in liver and viral diseases. Aligos is particularly focused on treatments for chronic hepatitis B (CHB) and metabolic dysfunction-associated steatohepatitis (MASH), as well as for coronaviruses.

The company’s lead candidate, ALG-010133, is a synthetic oligonucleotide currently in Phase I clinical trial for the treatment of CHB. Other promising candidates in their pipeline include ALG-000184, a capsid assembly modulator also targeting CHB, and ALG-055009, a small molecule thyroid hormone receptor beta (THR-ß) agonist for MASH. Initial studies on ALG-055009 have demonstrated enhanced potency and favorable pharmacokinetics.

Aligos is advancing its clinical programs, including the Phase 2a HERALD study of ALG-055009, which will assess the safety and efficacy of the drug in subjects with MASH, with topline data expected in Q4 2024. The study aims to enroll about 100 subjects and will evaluate multiple non-invasive biomarkers to track liver health improvements.

The company is also actively engaged in collaborations and partnerships to bolster its research efforts. Recently, Aligos presented positive data at the European Association for the Study of the Liver (EASL) Congress 2024, showcasing the sustained antiviral activity of ALG-000184 in both HBeAg-positive and HBeAg-negative CHB subjects. This data represents a significant advancement in viral load suppression and demonstrates Aligos' potential to deliver best-in-class treatments.

Besides its focus on liver diseases, Aligos is developing ALG-097558, a pan-coronavirus protease inhibitor showing promise in preclinical and early clinical trials. ALG-097558 has been well tolerated and does not require ritonavir boosting, addressing a critical need for effective, easily administered antiviral therapies.

Financially, Aligos reported cash, cash equivalents, and investments totaling $112.7 million as of March 31, 2024. The company continues to secure funding to support its operations and further its research projects, with a belief that its current cash balance will sustain operations through the end of 2025.

Aligos’ mission is to leverage its deep expertise and innovative approaches in drug development to become a leader in treating liver and viral diseases, ultimately improving patient outcomes and addressing high unmet medical needs worldwide.

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Aligos Therapeutics (ALGS) presented preliminary data for its S-antigen Transport-inhibiting Oligonucleotide Polymer, ALG-010133, at the EASL Digital International Liver Congress 2021. The Phase 1a/b trial showed that ALG-010133 was safe and well-tolerated in healthy volunteers, with no serious adverse events. Aligos also showcased additional CHB programs, indicating strong progress in chronic hepatitis B treatment development. The company plans to advance clinical trials for its candidates and expects to share further antiviral data in the second half of 2021.

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Aligos Therapeutics (Nasdaq: ALGS) is set to present five scientific abstracts at the EASL Digital International Liver Congress™ 2021 from June 23-26, 2021. The presentations will showcase their progress on chronic hepatitis B (CHB) treatments, including two candidates in Phase 1b studies. Both the STOPS™ molecule and CAPSID Assembly Modulator (CAM) are being evaluated in CHB patients, with preliminary data expected by H2 2021. Additionally, ASO and siRNA candidates are on track for clinical development in H2 2021 and H1 2022, respectively.

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Aligos Therapeutics, Inc. (Nasdaq: ALGS) announced promising results from its study on ALG-000184, presented at the HBV-TAG 2021 Conference. Subjects receiving 100 mg of ALG-000184 for 14 days showed a mean reduction of 2.9 log10 IU/mL in HBV DNA levels. Notably, 50% of subjects had HBV DNA below the lower limit of quantitation. The drug was well tolerated and demonstrated significant antiviral activity. Aligos plans to share more data later this year and continue developing its CHB programs.

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Aligos Therapeutics, a clinical stage biopharmaceutical company, announced that its CEO, Lawrence Blatt, will present at the Jefferies Virtual Healthcare Conference on June 3, 2021, from 2:00 to 2:25 PM ET. The presentation will include a virtual Q&A session. Interested parties can access the event via a webcast. The conference will feature over 400 companies and 3,000 investors discussing healthcare trends and investment opportunities.

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Aligos Therapeutics reported its Q1 2021 financial results, revealing a net loss of $27.7 million or $0.74 per share, up from a loss of $20.0 million or $7.56 per share in Q1 2020. R&D expenses increased to $22.9 million, driven by clinical trials for drug candidates ALG-010133 and ALG-000184. General and administrative expenses rose to $5.8 million. Cash reserves decreased from $243.5 million at the end of 2020 to $213.4 million. Despite pandemic challenges, Aligos remains on track with its clinical programs, aiming to commence trials for several candidates in the coming months.

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Aligos Therapeutics, Inc. (Nasdaq: ALGS) announced it will release its first quarter 2021 financial results on May 10, 2021, after market close. The company focuses on developing novel therapeutics for viral and liver diseases, particularly chronic hepatitis B and nonalcoholic steatohepatitis. Founded in 2018, Aligos aims to leverage its team's extensive drug development experience to advance its pipeline of targeted antiviral therapies.

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Aligos Therapeutics, Inc. (Nasdaq: ALGS) announced the appointment of James Scopa, J.D., MBA, to its board of directors on April 27, 2021. CEO Lawrence Blatt stated this addition supports Aligos' growth as it transitions towards mid-stage clinical trials for chronic hepatitis B. Scopa brings over 30 years of life sciences experience as an investor and advisor, positioning him to provide strategic guidance. He has previously held significant roles at MPM Capital and Deutsche Banc Alex. Brown, enhancing Aligos' leadership as it expands in viral and liver disease therapies.

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Aligos Therapeutics has commenced patient dosing in its ongoing study of ALG-000184, a drug candidate targeting chronic hepatitis B (CHB). This study evaluates ALG-000184's ability to inhibit viral replication by measuring HBV DNA and RNA levels. The company aims to combine ALG-000184 with other therapies to achieve better treatment outcomes. Preliminary data from previous trials indicate a favorable safety profile. Initial data on safety and antiviral activity are expected in the second half of 2021, contributing to Aligos' goal of improving CHB treatment regimens.

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Aligos Therapeutics (NASDAQ: ALGS) reported strong financial results for Q4 and the full year 2020, with cash reserves of $243.5 million following a successful IPO raising $167.2 million. The company advanced two drug candidates, ALG-010133 and ALG-000184, into clinical trials for Chronic Hepatitis B (CHB) and expects to generate safety and antiviral activity data in 2021. However, net losses reached $108.5 million for the year, up from $52.3 million in 2019, reflecting increased R&D expenses of $79.9 million.

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Aligos Therapeutics (Nasdaq: ALGS) has initiated dosing of its first drug candidate, ALG-010133, in chronic hepatitis B (CHB) patients as part of the ALG-010133-101 study. This proprietary molecule aims to reduce viral S-antigen levels, pivotal for HBV replication. Preclinical studies show promising inhibition of S-antigen. Currently, 72 healthy volunteers have been dosed, indicating an acceptable safety profile. Results from the initial patient cohorts are expected in the second half of 2021. Aligos aims to develop a treatment regimen that may lead to a functional cure for CHB.

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FAQ

What is the current stock price of Aligos Therapeutics (ALGS)?

The current stock price of Aligos Therapeutics (ALGS) is $43.42 as of January 3, 2025.

What is the market cap of Aligos Therapeutics (ALGS)?

The market cap of Aligos Therapeutics (ALGS) is approximately 148.2M.

What does Aligos Therapeutics focus on?

Aligos Therapeutics focuses on developing novel therapeutics for liver and viral diseases, particularly chronic hepatitis B (CHB) and metabolic dysfunction-associated steatohepatitis (MASH).

What is Aligos Therapeutics’ lead drug candidate?

The company’s lead drug candidate is ALG-010133, a synthetic oligonucleotide in Phase I clinical trial for the treatment of chronic hepatitis B (CHB).

What recent achievements has Aligos Therapeutics made?

Recent achievements include the initiation of the Phase 2a HERALD study for ALG-055009, and presenting positive data on ALG-000184 at the European Association for the Study of the Liver Congress 2024.

What is the Phase 2a HERALD study?

The Phase 2a HERALD study is a clinical trial evaluating ALG-055009 in subjects with metabolic dysfunction-associated steatohepatitis (MASH), with topline data expected in Q4 2024.

How is Aligos Therapeutics funded?

As of March 31, 2024, Aligos had cash, cash equivalents, and investments totaling $112.7 million, and aims to fund planned operations through the end of 2025.

Where is Aligos Therapeutics headquartered?

Aligos Therapeutics is headquartered in South San Francisco, California.

When was Aligos Therapeutics founded?

Aligos Therapeutics was founded in 2018.

What is ALG-097558?

ALG-097558 is a pan-coronavirus protease inhibitor developed by Aligos, which has shown promising results in preclinical and early clinical trials and does not require ritonavir boosting.

What are the financial results for Aligos Therapeutics’ first quarter 2024?

For Q1 2024, Aligos reported a net loss of $34.9 million, with cash, cash equivalents, and investments totaling $112.7 million as of March 31, 2024.

What is the mission of Aligos Therapeutics?

Aligos Therapeutics’ mission is to become a world leader in the treatment of liver and viral diseases, leveraging their expertise to develop best-in-class therapeutics for conditions like MASH and CHB.
Aligos Therapeutics, Inc.

Nasdaq:ALGS

ALGS Rankings

ALGS Stock Data

148.18M
2.85M
17.8%
48.86%
7.91%
Biotechnology
Biological Products, (no Disgnostic Substances)
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United States of America
SOUTH SAN FRANCISCO