Akouos to Present at the American Society of Gene and Cell Therapy 25th Annual Meeting

Rhea-AI Summary

Akouos, Inc. (NASDAQ: AKUS), a precision genetic medicine company focused on gene therapies for disabling hearing loss, will present new nonclinical data at the American Society of Gene and Cell Therapy (ASGCT) 25th Annual Meeting in Washington, D.C., from May 16 to 19, 2022. Key presentations include an oral session on AK-OTOF for otoferlin gene-mediated hearing loss and a poster discussing microRNA target sites for gene expression regulation in the inner ear. These findings support the clinical development of innovative therapies aimed at restoring hearing.

BOSTON, May 03, 2022 (GLOBE NEWSWIRE) -- Akouos, Inc. (NASDAQ: AKUS), a precision genetic medicine company dedicated to developing potential gene therapies for individuals living with disabling hearing loss worldwide, today announced that new nonclinical data will be presented at the American Society of Gene and Cell Therapy (ASGCT) 25^th Annual Meeting, which will take place in Washington, D.C. (both in-person and virtually) from May 16 to 19, 2022.

The company will give two presentations at the meeting: an oral presentation that highlights nonclinical data that support the clinical development of AK-OTOF, a gene therapy intended for the treatment of otoferlin gene (OTOF)-mediated hearing loss; and a poster that highlights nonclinical data supporting the potential use of microRNA target sites (miR-TS) in AAVAnc80 vectors for regulated gene expression in the inner ear. Details are as follows:

Oral Presentation Title: Nonclinical In Vivo Expression, Durability of Effect, Biodistribution/Shedding, and Safety Evaluations Support Clinical Development of AK-OTOF (AAVAnc80-hOTOF Vector) for OTOF-mediated Hearing Loss
Session Title: Ophthalmic and Auditory Diseases
Date/Time: Thursday, May 19, 2022 from 11:15 a.m. to 11:30 a.m. EDT
Room: Salon G
Presenting Author: Ann E. Hickox, Ph.D.
Abstract Number: 1233

Poster Presentation Title: Evaluating miR-Target Sites as a Strategy to Allow AAV Vector-based De-targeting of Gene Expression in the Inner Ear
Date/Time: Tuesday, May 17, 2022 at 5:30 p.m. EDT
Presenting Author: Richard M. Churchill Jr.
Abstract Number: 532
Poster Board Number: Tu-37

About Akouos
Akouos is a precision genetic medicine company dedicated to developing gene therapies with the potential to restore, improve, and preserve high-acuity physiologic hearing for individuals living with disabling hearing loss worldwide. Leveraging its precision genetic medicine platform that incorporates a proprietary adeno-associated viral (AAV) vector library and a novel delivery approach, Akouos is focused on developing precision therapies for forms of sensorineural hearing loss. Headquartered in Boston, Akouos was founded in 2016 by leaders in the fields of neurotology, genetics, inner ear drug delivery, and AAV gene therapy.

Contacts

Media:
Katie Engleman, 1AB
katie@1abmedia.com

Investors:
Courtney Turiano, Stern Investor Relations
Courtney.Turiano@sternir.com

FAQ

What will Akouos present at the ASGCT 25th Annual Meeting?

Akouos will present new nonclinical data on AK-OTOF gene therapy for otoferlin gene-mediated hearing loss and a study on microRNA target sites for gene expression in the inner ear.

When is the ASGCT 25th Annual Meeting?

The ASGCT 25th Annual Meeting will take place from May 16 to 19, 2022, in Washington, D.C.

What is the focus of Akouos's presentations at the ASGCT Meeting?

Akouos's presentations will focus on supporting the clinical development of gene therapies for hearing loss, specifically AK-OTOF and microRNA strategies.

Who will present on AK-OTOF at the ASGCT Meeting?

Ann E. Hickox, Ph.D., will present on AK-OTOF during the oral session on May 19, 2022.

What is the significance of Akouos's research presented at the ASGCT Meeting?

The research presented by Akouos could lead to innovative treatments for individuals suffering from disabling hearing loss.