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Adaptive Biotechnologies Corporation - ADPT STOCK NEWS

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Adaptive Biotechnologies Corporation (Nasdaq: ADPT) is a commercial-stage biotechnology company dedicated to leveraging the intricate biology of the adaptive immune system to innovate in the diagnosis and treatment of diseases. The company's proprietary immune medicine platform combines high-throughput sequencing with cutting-edge computational infrastructure to offer detailed analyses of T- and B-cell repertoires, critical elements in the body's immune response. Adaptive focuses on two primary business areas: Minimal Residual Disease (MRD) and Immune Medicine.

One of Adaptive's flagship products is clonoSEQ®, a highly sensitive and standardized test authorized by the FDA for detecting minimal residual disease (MRD) in patients with multiple myeloma (MM), B-cell acute lymphoblastic leukemia (B-ALL), and chronic lymphocytic leukemia (CLL). The clonoSEQ test is also available as a CLIA-validated laboratory developed test (LDT) for other lymphoid cancers, such as diffuse large B-cell lymphoma (DLBCL). The MRD status measured by clonoSEQ serves as a powerful predictor of patient outcomes, aiding in personalized treatment and monitoring strategies.

Adaptive Biotechnologies has formed strategic partnerships with leading biopharmaceutical companies. For instance, it collaborates with Genentech on T-cell receptor (TCR) based therapeutic products, providing a neoantigen-specific T-cell receptor identified using Adaptive's TCR discovery platform. The company also signed a multi-year collaboration with BeiGene to use clonoSEQ technology in developing novel therapies for lymphoid malignancies.

In terms of financial achievements, for the year ended December 31, 2023, Adaptive reported a total revenue of $170.3 million, with the MRD revenue contributing significantly to this growth. The company achieved substantial progress in clonoSEQ test volume and introduced strategic updates to maximize the value of its MRD and Immune Medicine businesses.

Adaptive Biotechnologies operates from biotech hubs in Seattle, Washington, and South San Francisco, California. Their team of world-class scientists and open, collaborative culture drive continuous innovation. The company's clinical diagnostics and pipeline developments aim to transform the clinical landscape, offering new hope for treating cancers, autoimmune disorders, and infectious diseases.

Recently, Adaptive Biotechnologies announced significant progress and strategic decisions to enhance its business operations. They integrated clonoSEQ into Epic’s specialty diagnostics suite, easing MRD monitoring accessibility for healthcare providers. The company continues to focus on driving operational efficiencies, as reflected by a decrease in operating expenses while maintaining sustainable growth.

Adaptive Biotechnologies remains committed to leveraging the adaptive immune system's potent capabilities to develop and commercialize immune-driven clinical products tailored to individual patient needs. With a robust cash position, Adaptive aims for profitability in its MRD business while making targeted investments in Immune Medicine.

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Adaptive Biotechnologies Corporation (Nasdaq: ADPT) will participate in the 39th Annual J.P. Morgan Healthcare Conference on January 11, 2021, at 1:30 p.m. PT / 4:30 p.m. ET. The presentation will showcase the company's advancements in translating the genetics of the adaptive immune system into clinical products for disease diagnosis and treatment. Interested individuals can access a live and archived webcast via the company’s website. Adaptive Biotechnologies focuses on developing immune-driven clinical products aimed at treating various diseases including cancer and autoimmune conditions.

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Adaptive Biotechnologies presents new data on its clonoSEQ Assay for assessing minimal residual disease (MRD) in patients with multiple myeloma at the ASH Annual Meeting. This FDA-cleared test demonstrates high accuracy in detecting residual cancer cells post-treatment. A study showed that MRD-informed treatment decisions led to a median progression-free survival of 97 months versus 75 months without treatment adjustment (p=0.006). The clonoSEQ Assay not only enhances patient outcomes but also offers potential cost savings, estimated at $916,000 annually per patient.

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Adaptive Biotechnologies Corporation (Nasdaq: ADPT) will present over 35 abstracts regarding its clonoSEQ® Assay at the ASH virtual 62nd Annual Meeting from December 5-8, 2020. This FDA-cleared assay assesses minimal residual disease (MRD) in blood cancers, including chronic lymphocytic leukemia (CLL) and multiple myeloma. Research indicates that MRD measurement correlates with enhanced patient outcomes and healthcare savings. The presentations aim to reinforce clonoSEQ as a vital tool for improving treatment decisions and patient management in hematologic malignancies.

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Adaptive Biotechnologies (Nasdaq: ADPT) announced the upcoming launch of T-Detect™ COVID, a groundbreaking T-cell test for past SARS-CoV-2 infections. In a study, T-Detect identified 97% of past infections, significantly outperforming antibody tests which detected only 77%. The research highlights the importance of T-cells in immunity, with findings indicating that some individuals may not develop detectable antibodies. This innovative test aims to provide a more comprehensive understanding of immune responses and will be the first clinical T-cell based diagnostic for COVID-19 infections, set to launch this fall.

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Adaptive Biotechnologies (Nasdaq: ADPT) announced a collaboration with GlaxoSmithKline (GSK) to utilize its clonoSEQ® Assay for assessing minimal residual disease (MRD) in GSK's hematology portfolio. The partnership aims to enhance treatment response monitoring and patient outcomes. The clonoSEQ Assay is the only FDA-authorized MRD test for multiple myeloma, chronic lymphocytic leukemia, and B-cell acute lymphoblastic leukemia. Adaptive will receive upfront and potential future milestone payments, though specific financial terms remain undisclosed.

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Adaptive Biotechnologies reported $26.3 million in revenue for Q3 2020, reflecting a 25% increase from Q2 2020 and a 1% year-over-year rise. Clinical sequencing volume surged 58%, totaling 4,023 tests. While development revenue grew by 5% to $15 million, sequencing revenue fell by 3% to $11.3 million. Operating expenses rose 44% to $63.3 million, contributing to a net loss of $36.7 million, up from $14 million in Q3 2019. The company refrained from providing financial guidance for 2020 due to ongoing COVID-19 uncertainties.

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Adaptive Biotechnologies (Nasdaq: ADPT) will release its third-quarter financial results on November 10, 2020, after market close. The company will host a conference call at 1:30 p.m. PT, with a webcast available via the Investors section of its website. Adaptive focuses on leveraging the adaptive immune system's genetics to develop clinical diagnostics and therapeutics, aiming to address diseases like cancer and autoimmune conditions. The firm currently has two commercial products and an expansive clinical pipeline.

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Adaptive Biotechnologies Corporation (Nasdaq: ADPT) will participate in the Morgan Stanley Virtual Healthcare Conference on September 15, 2020, at 10:15 a.m. PT / 1:15 p.m. ET. The company aims to decode the adaptive immune system for disease diagnosis and treatment, boasting two commercial products and a strong clinical pipeline. Interested parties can access a live and archived webcast of the presentation via the company's website. Adaptive Biotechnologies is focused on developing immune-driven clinical products tailored to individual patients.

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Adaptive Biotechnologies Corporation (Nasdaq: ADPT) announced participation in the UBS Genomics 2.0 and Medtech Innovations Virtual Summit on August 11, 2020. The management team will engage in a fireside chat at 11:00 a.m. Pacific Time, which will also be available via webcast on the company's website. Adaptive Biotechnologies focuses on leveraging the adaptive immune system to create diagnostics and treatments for diseases, including cancer and autoimmune conditions. The company aims to develop tailored immune-driven clinical products, backed by a robust clinical pipeline and two commercial offerings.

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Adaptive Biotechnologies has received FDA clearance for its clonoSEQ® Assay, the first assay approved for monitoring minimal residual disease (MRD) in chronic lymphocytic leukemia (CLL) patients using blood samples. This significant advancement expands previous FDA approvals for MRD detection in bone marrow for multiple myeloma and B-cell acute lymphoblastic leukemia (ALL). The assay's sensitivity allows for early detection of cancer recurrence, enhancing patient management. Medicare coverage supports access to this innovative testing method, crucial for the mostly elderly CLL patient population.

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FAQ

What is the current stock price of Adaptive Biotechnologies Corporation (ADPT)?

The current stock price of Adaptive Biotechnologies Corporation (ADPT) is $4.37 as of November 21, 2024.

What is the market cap of Adaptive Biotechnologies Corporation (ADPT)?

The market cap of Adaptive Biotechnologies Corporation (ADPT) is approximately 638.9M.

What is Adaptive Biotechnologies Corporation known for?

Adaptive Biotechnologies is known for its proprietary immune medicine platform that analyzes T- and B-cell repertoires to innovate in disease diagnosis and treatment, particularly through its clonoSEQ test for minimal residual disease (MRD).

What is clonoSEQ?

clonoSEQ is an FDA-authorized test for detecting minimal residual disease (MRD) in patients with multiple myeloma (MM), B-cell acute lymphoblastic leukemia (B-ALL), and chronic lymphocytic leukemia (CLL). It is also available as a laboratory-developed test (LDT) for other lymphoid cancers.

Who are some of Adaptive Biotechnologies' key partners?

Adaptive collaborates with leading biopharmaceutical companies like Genentech and BeiGene to develop innovative therapies, particularly focusing on T-cell receptor (TCR) based therapeutic products and MRD assessment.

What were Adaptive Biotechnologies' financial highlights for 2023?

Adaptive reported a total revenue of $170.3 million for the year ended December 31, 2023, with significant contributions from its MRD business. The company also achieved substantial progress in clonoSEQ test volume.

How does Adaptive Biotechnologies contribute to personalized medicine?

Adaptive's immune medicine platform and products like clonoSEQ enable personalized diagnosis, monitoring, and treatment of diseases by leveraging detailed immune system analyses to tailor clinical products to individual patient needs.

What recent strategic decisions has Adaptive Biotechnologies made?

Adaptive has focused on driving operational efficiencies, integrating clonoSEQ into Epic’s diagnostics suite for easier MRD monitoring, and enhancing the independence of its MRD and Immune Medicine businesses to maximize shareholder value.

Where are Adaptive Biotechnologies' main operations located?

Adaptive Biotechnologies operates from biotech hubs in Seattle, Washington, and South San Francisco, California.

What is the company culture at Adaptive Biotechnologies?

Adaptive's culture emphasizes hard work, collaboration, open communication, and innovation, driven by a passionate team committed to making a difference in the world.

What are some key clinical applications of clonoSEQ?

clonoSEQ is used for MRD assessment to predict patient outcomes, evaluate treatment response, and inform clinical decisions in diseases like multiple myeloma, B-ALL, CLL, and other lymphoid cancers.

What are Adaptive Biotechnologies' future goals?

Adaptive aims to continue developing and commercializing immune-driven clinical products tailored to individual patient needs while achieving profitability in its MRD business and advancing key programs in Immune Medicine through targeted investments.

Adaptive Biotechnologies Corporation

Nasdaq:ADPT

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Biotechnology
Biological Products, (no Disgnostic Substances)
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United States of America
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