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Alpha Cognition Inc. (CSE: ACOG, OTCQB: ACOGF) is a clinical-stage biopharmaceutical company dedicated to developing treatments for patients suffering from neurodegenerative diseases. The company is primarily focused on addressing conditions like Alzheimer’s disease and Cognitive Impairment with mild Traumatic Brain Injury (mTBI), which currently lack approved treatment options.
Alpha Cognition's flagship product, ALPHA-1062, is a patented new chemical entity in development as a next-generation acetylcholinesterase inhibitor for the treatment of mild-to-moderate Alzheimer’s disease. Designed to minimize gastrointestinal side effects, ALPHA-1062's active metabolite is differentiated from existing therapies like donepezil and rivastigmine. The compound binds to neuronal nicotinic receptors, notably the alpha-7 subtype, which is known to positively affect cognition. ALPHA-1062 is also being developed in combination with memantine for moderate to severe Alzheimer’s dementia and as an intranasal formulation for Cognitive Impairment with mTBI.
In recent developments, Alpha Cognition has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for ALPHA-1062, with an expected approval date in the second half of 2024. This milestone underscores the company's commitment to advancing patient care and highlights their robust pipeline of innovative treatments.
Alpha Cognition has also received significant recognition in the form of patents and grants. The company was recently awarded a $750,000 research and development grant from the U.S. Department of Defense to study ALPHA-1062's potential in treating mTBI. Additionally, the company holds multiple patents for ALPHA-1062, including a new composition-of-matter patent that extends protection into 2044.
The company's financial strategy includes successfully raising gross proceeds of $8.45 million through private placements, which will be used for research and development, general and administrative matters, and working capital. This funding is crucial for furthering the development and potential commercialization of their lead product, ALPHA-1062.
Alpha Cognition's commercialization strategy aims to initially target the Long Term Care (LTC) market, followed by the broader Neurology segment once payer reimbursement is established. This approach is expected to maximize the impact of ALPHA-1062 in the Alzheimer’s treatment landscape.
Overall, Alpha Cognition Inc. is poised for a transformational year with significant advancements in their pipeline, financial health, and strategic positioning to bring innovative therapies to market for neurodegenerative diseases.
Alpha Cognition Inc. (TSX-V:ACOG, OTCQB:ACOGF), a biopharmaceutical company focused on neurodegenerative disorders, will present at the Planet MicroCap Showcase: VEGAS 2023 on April 26, 2023, at 10:30 AM PST. CEO Michael McFadden will lead the presentation and answer questions afterward. Interested investors can attend live via webcast or schedule one-on-one meetings at the conference in Las Vegas. Alpha Cognition is developing ALPHA-1062, a new treatment aimed at Alzheimer's disease, designed to minimize gastrointestinal side effects. Further details can be found on the Planet MicroCap website.
Alpha Cognition Inc. (TSX-V: ACOG, OTCQB: ACOGF) has completed a second tranche of its private placement, issuing 6,952,427 units at $0.255 per unit, yielding gross proceeds of $1,772,869. This follows a first tranche, bringing total proceeds to $6,055,650 from 23,747,648 units. The funds will support clinical development programs, including a New Drug Application for ALPHA-1062, a new treatment for Alzheimer's disease. Securities are subject to a four-month hold period in Canada and a 12-month resale restriction in the U.S.
Alpha Cognition Inc. (TSX-V: ACOG, OTCQB: ACOGF) reported its financial results for Q4 and the full year ending December 31, 2022. The company is focused on submitting a New Drug Application (NDA) for ALPHA-1062, aimed at treating mild to moderate Alzheimer's disease, targeting a filing date in June/July 2023. Notably, R&D expenses increased to $8.8 million for 2022, driven by advancements in clinical studies. The company reported a net loss of $12.1 million for the year, with cash reserves of $2.1 million as of December 31, 2022. There is an ongoing effort to manage finances prudently and explore partnerships.
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