Welcome to our dedicated page for Adicet Bio news (Ticker: ACET), a resource for investors and traders seeking the latest updates and insights on Adicet Bio stock.
Adicet Bio, Inc. (Nasdaq: ACET) is a clinical-stage biotechnology company engaged in the discovery and development of novel allogeneic gamma delta T cell therapies for the treatment of autoimmune diseases and cancer. Leveraging advanced immunotherapy techniques, Adicet Bio is pioneering the use of gamma delta T cells engineered with chimeric antigen receptors (CARs) and T cell receptors (TCRs) to create 'off-the-shelf' therapies aimed at providing durable and effective treatments for patients.
Core Products and Pipeline:
- ADI-001: A first-in-class allogeneic gamma delta T cell therapy expressing a CAR targeting CD20, currently in a Phase 1 clinical trial for relapsed or refractory aggressive B cell non-Hodgkin's lymphoma and autoimmune diseases such as lupus nephritis.
- ADI-270: An armored gamma delta CAR T cell product candidate targeting CD70, in preclinical development for renal cell carcinoma and other CD70+ solid and hematological malignancies.
Recent Achievements and Collaborations:
- FDA clearance of the Investigational New Drug (IND) application for ADI-001 in lupus nephritis and initiation of Phase 1 clinical trial expected in 2Q 2024.
- Strategic collaboration with Regeneron Pharmaceuticals, Inc. to develop next-generation engineered immune-cell therapeutics.
- Successful Series A financing round, raising $51 million led by Orbimed Partners, Orbimed Israel, and Novartis Ventures.
- Inducement awards granted to new employees as material inducements for employment, signifying ongoing growth and talent acquisition within the company.
- Presentation of promising preclinical data on ADI-270 at major scientific annual meetings, indicating robust anti-tumor activity and potential clinical benefits.
Financial Overview: Adicet Bio maintains a strong cash position with $247.6 million in cash and cash equivalents as of March 31, 2024, providing sufficient funding to support operations into the second half of 2026. The company continues to strategically invest in research and development, as well as in expanding its organizational capabilities.
Adicet Bio is at the forefront of innovation in the biotechnology space, striving to bring transformative therapies to patients with unmet medical needs. For more information, please visit Adicet Bio's official website.
Adicet Bio, Inc. (NASDAQ: ACET) announced the granting of inducement awards on February 28, 2023, to four employees hired in February 2023. These awards consist of non-qualified stock options totaling 105,400 shares at an exercise price of $7.88 per share, equal to the stock’s closing price on the grant date. Vesting is structured with 25% after one year and the remaining shares vesting in 36 equal monthly installments, dependent on continued employment. The awards were made under the company’s 2022 Inducement Plan, authorized by the board's independent compensation committee, in compliance with Nasdaq rules.
Adicet Bio, Inc. (Nasdaq: ACET) is set to have its President and CEO, Chen Schor, participate in a fireside chat at the 2023 Guggenheim Oncology Conference on February 9, 2023, at 2:10 p.m. ET. This conference focuses on the development of allogeneic gamma delta T cell therapies for cancer, which are engineered to enhance tumor targeting and boost immune responses. Investors can access the live audio webcast on Adicet's website, with an archived replay available for 30 days post-event. For further details on Adicet's innovative therapies, visit Adicet Bio's website.
Adicet Bio, Inc. (NASDAQ: ACET) announced on January 31, 2023, that it granted inducement awards to six new employees, comprising non-qualified stock options for 72,800 shares at an exercise price of $9.15. These options will vest over four years, with one-fourth vesting on the one-year anniversary of each employee's start date and the remainder vesting in thirty-six equal monthly installments. This award was granted pursuant to the 2022 Inducement Plan, amended in January 2023, endorsed by the independent compensation committee to attract talent in compliance with Nasdaq Listing Rule 5635(c)(4).
Adicet Bio, Inc. (ACET) reported positive Phase 1 trial results for its investigational therapy, ADI-001, targeting relapsed/refractory B-cell non-Hodgkin lymphoma (NHL). As of December 5, 2022, ADI-001 exhibited a 75% overall response rate (ORR) and a 69% complete response (CR) rate across all doses. Notably, in five patients previously treated with CAR T therapy, the ORR and CR were both 100%. The company aims to initiate pivotal studies in 2023, potentially leading to regulatory applications. No significant safety issues were reported, with treatment deemed well-tolerated.
Adicet Bio, Inc. (NASDAQ: ACET) will host a webcast on December 11, 2022, at 9:00 a.m. EST, to discuss the latest data from its Phase 1 study of ADI-001, targeting relapsed or refractory B-cell NHL. The presentation will feature Dr. Sattva Neelapu from MD Anderson Cancer Center, along with the Adicet management team. Participants can register on Adicet's website. An archived replay will be accessible for 30 days post-event. The company is focused on allogeneic gamma delta T cell therapies for cancer treatment.
Adicet Bio, Inc. (NASDAQ: ACET) announced on November 30, 2022, the grant of inducement awards to three new employees, totaling 38,400 stock options with an exercise price of $18.18 per share. Additionally, Dr. Nancy Boman, the company's newly appointed Senior VP and Chief Regulatory Officer, received an award for 136,000 stock options at the same exercise price. The options will vest over four years, contingent on continued employment. These grants were made outside the stockholder-approved equity plans, aligning with Nasdaq rules.
Adicet Bio, Inc. (NASDAQ: ACET) has announced that CEO Chen Schor will present at the virtual JMP Securities Hematology and Oncology Summit on December 6, 2022, at 9:40 a.m. ET. The presentation will focus on the company’s advancements in allogeneic gamma delta T cell therapies for cancer. Investors can access the live audio webcast on Adicet's website, with a replay available for 30 days post-event. Adicet is focused on engineered T cells aimed at enhancing anti-tumor responses, showcasing their innovative approach in oncology.
Adicet Bio, Inc. (NASDAQ: ACET) has appointed Nancy Boman, M.D., Ph.D., as Senior Vice President and Chief Regulatory Officer. Dr. Boman will lead the regulatory strategy to enhance Adicet's gamma delta T cell therapy pipeline, including the initiation of a pivotal program for ADI-001 in the first half of 2023 and an IND application for ADI-925 in the second half of 2023. With nearly 30 years of experience in regulatory affairs, Dr. Boman previously held key roles at Encoded Therapeutics and AveXis, overseeing successful marketing applications.
Adicet Bio (ACET) reported promising safety and efficacy data for its lead candidate, ADI-001, targeting relapsed or refractory B-cell non-Hodgkin’s lymphoma. As of September 30, 2022, cash and cash equivalents were $282.7 million, providing a runway into the first half of 2025. R&D expenses rose to $16.6 million from $11.9 million year-over-year, while the net loss was $22.0 million, or $0.53 per share. The company plans to present updated data at the ASH Annual Meeting in December 2022 and outline new pipeline candidates at an R&D webcast on November 10, 2022.
Adicet Bio (ACET) announces promising preclinical data from four new gamma delta T cell therapy programs, showcased at the Society for Immunotherapy of Cancer's 37th Annual Meeting. The company plans to submit Investigational New Drug applications in the second half of 2023. CEO Chen Schor highlighted these developments as vital for advancing innovative cancer treatments. Adicet aims to enhance tumor targeting with its engineered therapies, which have shown increased efficacy in preclinical models. A detailed webcast is scheduled for November 10, 2022, to discuss these findings further.
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