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Adicet Bio, Inc. - ACET STOCK NEWS

Welcome to our dedicated page for Adicet Bio news (Ticker: ACET), a resource for investors and traders seeking the latest updates and insights on Adicet Bio stock.

Adicet Bio, Inc. (Nasdaq: ACET) is a clinical-stage biotechnology company engaged in the discovery and development of novel allogeneic gamma delta T cell therapies for the treatment of autoimmune diseases and cancer. Leveraging advanced immunotherapy techniques, Adicet Bio is pioneering the use of gamma delta T cells engineered with chimeric antigen receptors (CARs) and T cell receptors (TCRs) to create 'off-the-shelf' therapies aimed at providing durable and effective treatments for patients.

Core Products and Pipeline:

  • ADI-001: A first-in-class allogeneic gamma delta T cell therapy expressing a CAR targeting CD20, currently in a Phase 1 clinical trial for relapsed or refractory aggressive B cell non-Hodgkin's lymphoma and autoimmune diseases such as lupus nephritis.
  • ADI-270: An armored gamma delta CAR T cell product candidate targeting CD70, in preclinical development for renal cell carcinoma and other CD70+ solid and hematological malignancies.

Recent Achievements and Collaborations:

  • FDA clearance of the Investigational New Drug (IND) application for ADI-001 in lupus nephritis and initiation of Phase 1 clinical trial expected in 2Q 2024.
  • Strategic collaboration with Regeneron Pharmaceuticals, Inc. to develop next-generation engineered immune-cell therapeutics.
  • Successful Series A financing round, raising $51 million led by Orbimed Partners, Orbimed Israel, and Novartis Ventures.
  • Inducement awards granted to new employees as material inducements for employment, signifying ongoing growth and talent acquisition within the company.
  • Presentation of promising preclinical data on ADI-270 at major scientific annual meetings, indicating robust anti-tumor activity and potential clinical benefits.

Financial Overview: Adicet Bio maintains a strong cash position with $247.6 million in cash and cash equivalents as of March 31, 2024, providing sufficient funding to support operations into the second half of 2026. The company continues to strategically invest in research and development, as well as in expanding its organizational capabilities.

Adicet Bio is at the forefront of innovation in the biotechnology space, striving to bring transformative therapies to patients with unmet medical needs. For more information, please visit Adicet Bio's official website.

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Adicet Bio, Inc. (Nasdaq: ACET) announced the granting of inducement awards on May 31, 2022, as part of its 2022 Inducement Plan to four employees hired in May 2022. The awards consist of non-qualified stock options for a total of 100,800 shares with an exercise price of $11.82 per share, the closing price on the grant date. The vesting schedule allows for one-fourth of the options to vest annually, with complete vesting occurring over four years, contingent on continued employment.

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Adicet Bio, Inc. (ACET) announced positive preliminary results from its Phase 1 trial of ADI-001 for relapsed/refractory B-cell Non-Hodgkin’s Lymphoma (NHL). As of February 14, 2022, the therapy showed a 67% complete response rate and a favorable safety profile, with no Grade ≥ 3 adverse events. Updated data will be presented at the ASCO Annual Meeting on June 6, 2022. Two patients maintained their complete response for over three months, despite one patient’s unrelated COVID-19 complications.

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Adicet Bio, Inc. (Nasdaq: ACET), a clinical stage biotechnology company, announced participation in two investor conferences in May and June 2022. The H.C. Wainwright Global Investment Conference will occur from May 23-26, with an on-demand presentation available from May 24 at 7:00 A.M. ET. The Jefferies Healthcare Conference runs from June 8-10, featuring a presentation by CEO Chen Schor on June 10 at 8:30 A.M. ET. Live webcasts will be accessible via Adicet’s Investors section on their website.

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Adicet Bio, Inc. (Nasdaq: ACET) announced its financial results for Q1 2022, reporting a net income of $4.6 million, compared to a net loss of $21.3 million in the same period last year. The company maintains a strong cash position with $277.9 million as of March 31, 2022. Significant operational highlights include the acceptance of interim data from the ADI-001 Phase 1 trial for oral presentation at the ASCO Annual Meeting and the granting of Fast Track Designation by the FDA for ADI-001 targeting Non-Hodgkin’s lymphoma. R&D expenses rose to $13.5 million.

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Adicet Bio, Inc. (Nasdaq: ACET) presented promising preclinical data for ADI-001 during the ISCT Annual Meeting. The study highlighted ADI-001's strong in vitro and in vivo tumor growth inhibition across various human lymphoma cell lines, showcasing its adaptive and innate anti-tumor mechanisms. Notably, the non-gene-edited ADI-001 CAR T cells exhibited enhanced resilience against host-mediated clearance compared to gene-edited alternatives. ADI-001 is currently undergoing a Phase 1 clinical trial aimed at treating relapsed or refractory B-cell Non-Hodgkin’s lymphoma.

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Adicet Bio, Inc. (NASDAQ: ACET), a clinical-stage biotechnology company, announced the granting of inducement awards on April 29, 2022, to four newly hired employees. The awards include non-qualified stock options to purchase a total of 62,000 shares at an exercise price of $14.74 per share, equal to the stock's closing price on that date. The vesting schedule allows for one-fourth of the shares to vest after one year, with the remainder vesting in monthly installments over three years. These awards were granted under Adicet's 2022 Inducement Plan, adopted in January 2022.

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Adicet Bio, Inc. (NASDAQ: ACET) announced updated safety and efficacy data from the Phase 1 study of ADI-001 for treating relapsed or refractory B-cell Non-Hodgkin’s Lymphoma. This data will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting from June 3-7, 2022. The oral presentation, titled 'A phase 1 study of ADI-001: Anti-CD20 CAR-engineered allogeneic gamma delta T cells in adults with B-cell malignancies', is scheduled for June 6, 2022, at 8:00 AM CDT, featuring Sattva Neelapu, MD, from MD Anderson Cancer Center.

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Adicet Bio (Nasdaq: ACET) has announced that the FDA granted Fast Track Designation to its lead program ADI-001, targeting CD20 for treating relapsed or refractory B-cell Non-Hodgkin’s lymphoma. This investigational therapy is currently in a Phase 1 study assessing its safety and tolerability. The Fast Track status accelerates its development, addressing an unmet need in adult NHL. CEO Chen Schor expressed optimism about ADI-001’s unique approach and anticipates further data release from the trial in early 2022.

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Adicet Bio, Inc. (NASDAQ: ACET), a clinical-stage biotechnology firm, is advancing allogeneic gamma delta CAR T cell therapies for cancer. The company will participate in two investor conferences in April 2022. On April 14, CEO Chen Schor will join a panel at the Canaccord Genuity 2022 Horizons in Oncology Virtual Conference. Additionally, Adicet's management will conduct 1x1 meetings at the Jefferies Biotech on the Bay Summit in Miami, Florida on April 27, 2022. These events showcase Adicet's commitment to innovative cancer therapy development.

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Adicet Bio, Inc. (NASDAQ: ACET) announced the granting of inducement awards on March 31, 2022, to two new employees as part of its 2022 Inducement Plan. The awards consist of non-qualified stock options to purchase a total of 36,000 shares at an exercise price of $19.97 per share, which reflects the closing price on the Grant Date. The options will vest progressively over four years, subject to continued employment. This plan was approved by an independent compensation committee in compliance with Nasdaq Listing Rule 5635(c)(4).

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FAQ

What is the current stock price of Adicet Bio (ACET)?

The current stock price of Adicet Bio (ACET) is $0.914 as of November 21, 2024.

What is the market cap of Adicet Bio (ACET)?

The market cap of Adicet Bio (ACET) is approximately 78.3M.

What is Adicet Bio, Inc.?

Adicet Bio, Inc. is a clinical-stage biotechnology company focused on developing allogeneic gamma delta T cell therapies for the treatment of autoimmune diseases and cancer.

What are the key products in Adicet Bio's pipeline?

The key products include ADI-001, a CAR T cell therapy targeting CD20 for autoimmune diseases and aggressive B cell non-Hodgkin's lymphoma, and ADI-270, an armored CAR T cell candidate targeting CD70 for renal cell carcinoma.

What recent achievements has Adicet Bio made?

Recent achievements include FDA clearance for ADI-001 in lupus nephritis, successful strategic collaborations, significant financing rounds, and promising preclinical data presentations.

How is Adicet Bio financially positioned?

Adicet Bio has a strong cash position with $247.6 million in cash and equivalents as of March 31, 2024, funding operations into the second half of 2026.

What strategic collaborations has Adicet Bio entered into?

Adicet Bio has a strategic collaboration with Regeneron Pharmaceuticals to develop engineered immune-cell therapeutics using its gamma delta T cell allogeneic platform technology.

What is the focus of Adicet Bio's research and development?

Adicet Bio's R&D focuses on creating 'off-the-shelf' gamma delta T cell therapies engineered with CARs and TCRs for cancer and autoimmune diseases.

What are ADI-001 and ADI-270?

ADI-001 is a gamma delta T cell therapy targeting CD20 for non-Hodgkin's lymphoma and autoimmune diseases, while ADI-270 targets CD70 for renal cell carcinoma and other CD70+ cancers.

What makes Adicet Bio's approach unique?

Adicet Bio utilizes gamma delta T cells with CAR and TCR engineering, providing off-the-shelf, allogeneic therapies that offer durable and effective treatments for patients.

What is the significance of the FDA's fast track designation for ADI-001?

The fast track designation for ADI-001 by the FDA facilitates the development and expedites the review process for this promising therapy targeting lupus nephritis.

Where can I find more information about Adicet Bio?

For more information, visit Adicet Bio's official website at https://www.adicetbio.com.

Adicet Bio, Inc.

Nasdaq:ACET

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78.28M
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1.59%
76.44%
4.16%
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