Agilent Announces New Oligonucleotide Analysis Software for Biopharma Research

Rhea-AI Summary

Agilent Technologies Inc. (NYSE: A) launched MassHunter BioConfirm 12.0 software, enhancing analysis for oligonucleotides in drug development. This update supports high-resolution LC/MS data, significantly improving oligonucleotide purity and sequence confirmation assessments. The software's new features allow researchers to confirm sequences in minutes instead of days, demonstrating Agilent's commitment to biopharma solutions. The software will be showcased at the 70th ASMS Conference in Minneapolis, from June 5-9, 2022.

Positive

• Launch of MassHunter BioConfirm 12.0 improves oligonucleotide purity and sequence confirmation.
• Software reduces sequence confirmation time from days to minutes.
• Increased capabilities align with rising customer demand in the biopharma sector.

Negative

• None.

SANTA CLARA, Calif.--(BUSINESS WIRE)-- Agilent Technologies Inc. (NYSE: A) today announced the release of its MassHunter BioConfirm 12.0 software, which now supports data generated by Agilent high-resolution LC/MS for oligonucleotide purity analysis and sequence confirmation. MassHunter BioConfirm 12.0 will be on show at the 70th ASMS Conference on Mass Spectrometry and Allied Topics being held June 5 - 9, 2022 in Minneapolis, Minnesota.

Oligonucleotides are a class of molecules attracting increased interest as therapeutics in the biopharma industry. Oligonucleotides target gene expression through several mechanisms and offer considerable promise for addressing a wide range of diseases. However, challenges remain in developing oligonucleotide-based biotherapeutics, including finding ways to enhance their in vivo stability, more confidently and precisely target their delivery, and quickly confirm sequences.

Agilent MassHunter BioConfirm 12.0 software introduces enhancements to existing capabilities for protein analysis and adds support for oligonucleotide analysis. The addition of oligonucleotide support significantly extends the capabilities of MassHunter BioConfirm, adding critical functionality for assessing oligonucleotide purity and sequence confirmation – important analytical steps in the use of oligonucleotides for biotherapeutics and vaccine research and development.

"Customer requests for oligonucleotide analysis capabilities have been steadily increasing. With MassHunter BioConfirm 12.0, support for oligonucleotide analysis is available for the first time,” said Sudharshana Seshadri, vice president and general manager of Agilent’s Mass Spectrometry Division. “Agilent has a strong commitment to expanding its biopharma solutions, especially MS-based solutions. The addition of oligonucleotide support to MassHunter BioConfirm aligns with Agilent’s continued focus on the needs of our biopharma customers."

“I’m excited about the new oligonucleotide analysis package Agilent has developed. Identification of impurities and sequencing of oligonucleotides has previously been a slow and laborious process,” said Leo Joyce, Ph.D., senior chemist III at Arrowhead Pharmaceuticals. “The integrated BioConfirm 12.0 workflow is very easy to use and generates accurate results quickly. This software represents significant time and resource savings compared to the traditional approach.”

The new MassHunter BioConfirm 12.0 workflows allow researchers to identify full-length products and potential impurities. The innovative MS/MS-based sequence confirmation enables confirmation of oligonucleotide sequences in minutes instead of days or weeks of manual interpretation. MassHunter BioConfirm 12.0 also has the built-in flexibility for software customization to accommodate specific oligo nomenclatures and continues to provide support to ensure regulatory compliance and preservation of data integrity.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global leader in the life sciences, diagnostics, and applied chemical markets, delivering insight and innovation that advance the quality of life. Agilent’s full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers' most challenging questions. The company generated revenue of $6.32 billion in fiscal 2021 and employs 17,000 people worldwide. Information about Agilent is available at www.agilent.com. To receive the latest Agilent news, please subscribe to the Agilent Newsroom. Follow Agilent on LinkedIn, Twitter, and Facebook.

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Media Contact

Naomi Goumillout

Agilent Technologies

+1.781.266.2819

naomi.goumillout@agilent.com

Source: Agilent Technologies Inc.

FAQ

What is MassHunter BioConfirm 12.0?

MassHunter BioConfirm 12.0 is Agilent's software for enhancing oligonucleotide purity analysis and sequence confirmation.

When was MassHunter BioConfirm 12.0 launched?

MassHunter BioConfirm 12.0 was announced on June 6, 2022.

What are the benefits of MassHunter BioConfirm 12.0?

It allows for faster identification of oligonucleotide sequences and impurities, improving efficiency in biopharma research.

Where will MassHunter BioConfirm 12.0 be showcased?

It will be showcased at the 70th ASMS Conference in Minneapolis from June 5-9, 2022.

How does MassHunter BioConfirm 12.0 support biopharma development?

It provides critical functionality for oligonucleotide analysis, aiding in the development of targeted therapeutics.