Agilent Announces Cell Analysis Workflow Automation for Immuno-Oncology, Virology, and Vaccine Development Markets

Rhea-AI Summary

Agilent Technologies (NYSE: A) announces the integration of its xCELLigence RTCA HT platform with the BioTek BioSpa 8 Automated Incubator, enhancing workflow automation in immuno-oncology and vaccine development. This combination allows for label-free, non-invasive analysis of cell proliferation, significantly increasing throughput and reducing sample sizes. The BioSpa 8 provides precise environmental controls, enabling researchers to automate assays with real-time data analysis. This innovative solution aims to expedite drug candidate screening amidst challenges in the evolving pharma landscape, reflecting Agilent's commitment to addressing critical health concerns.

Positive

• Integration of xCELLigence RTCA HT with BioTek BioSpa 8 enhances automation, increasing efficiency in drug candidate screening.
• Allows for label-free analysis, improving throughput and decreasing sample sizes, crucial for immuno-oncology and vaccine development.

Negative

• None.

New workflow integrates the xCELLigence RTCA HT with the BioTek BioSpa 8 Automated Incubator

SANTA CLARA, Calif.--(BUSINESS WIRE)-- Agilent Technologies Inc. (NYSE: A) today announced their xCELLigence RTCA HT (real-time cell analysis high-throughput) platform now integrates with the BioTek BioSpa 8 Automated Incubator. Developed in response to market needs, this combination enables a higher level of workflow automation that provides novel functionality for the development of label-free high-throughput potency assays for the immuno-oncology space and high-throughput viral cytopathic effects (CPE) assays for the vaccine market.

Faced with fierce competition to fulfill the promise of immuno-oncology therapeutics, pharma researchers are rapidly evolving the approaches used to accelerate clinical success. Similarly, vaccine developers are under unprecedented pressure in light of constantly shifting public health threats. Automated workflows offer the promise of increasing drug candidate screening as a means to more quickly and efficiently translate research into discovery. However, many existing automated workflow solutions still rely on substantial manual intervention steps that hinder throughput and limit the scope of assay development.

The xCELLigence RTCA HT - BioSpa 8 integration offers a label-free, non-invasive, kinetic readout of cell proliferation and cytotoxicity that allows researchers to analyze up to eight 384-well E-Plates, increasing throughput and decreasing sample sizes. The BioSpa 8 incubator provides real-time temperature and CO₂/O₂ control with humidity monitoring. The xCELLigence instrument is equipped with a heated cradle, so cells are protected against unnecessary perturbances and fluctuation of culture conditions during the automated transfer from the incubator. User-friendly software facilitates automated assays and data analysis, making this a true walk-away system for identifying therapeutics to fight disease and providing a degree of automation that is unique to this combination of technologies.

“This is an innovative solution for immuno-oncology therapeutic and vaccine development, demonstrating Agilent’s ongoing commitment to fight cancer and infectious diseases,” said Todd Christian, vice president and general manager of Agilent’s Cell Analysis Division. “Integrating our non-invasive and real-time cell analysis measurement capabilities and physiological incubation provides a simple, automated workflow for increased throughput and screening flexibility under physiological conditions.”

“The xCELLigence RTCA HT technology has been key to facilitating high-throughput, rapid, and quantitative cytopathic effect (CPE) monitoring as a tool to assess neutralizing activity and potency,” said Dr. Robert Carnahan, associate director of the Vanderbilt Vaccine Center at the Vanderbilt University Medical Center. “We were able to bypass a multitude of hands-on, multistep processes required by plaque or focus-forming assays to measure viral activity.”

Agilent provides products and services that facilitate drug discovery across a broad range of disciplines and approaches, including tools for real-time cell and metabolic analysis, as well as flow cytometric, plate-based, and imaging/microscopy platforms. Announcement of this new integrated solution reinforces our commitment as a partner for solving real-world challenges in the drug development space.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global leader in the life sciences, diagnostics, and applied chemical markets, delivering insight and innovation that advance the quality of life. Agilent’s full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers' most challenging questions. The company generated revenue of $6.85 billion in fiscal 2022 and employs 18,000 people worldwide. Information about Agilent is available at www.agilent.com. To receive the latest Agilent news, please subscribe to the Agilent Newsroom. Follow Agilent on LinkedIn and Facebook.

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MEDIA CONTACT

Naomi Goumillout

Agilent Technologies

+1.781.266.2819

naomi.goumillout@agilent.com

Source: Agilent Technologies Inc.

FAQ

What is Agilent Technologies' latest integration announcement regarding stock NYSE: A?

Agilent Technologies announced the integration of xCELLigence RTCA HT with BioTek BioSpa 8 Automated Incubator.

How does the new integration benefit researchers in the immuno-oncology sector?

The integration enhances automation and provides label-free, non-invasive analysis of cell proliferation, improving throughput and efficiency.

What are the key features of the BioTek BioSpa 8 Automated Incubator?

The BioTek BioSpa 8 offers real-time control of temperature, CO2/O2 levels, and humidity, facilitating optimal assay conditions.

When was the integration of xCELLigence RTCA HT and BioTek BioSpa 8 announced?

The integration was announced on February 24, 2023.

What revenue did Agilent Technologies report in fiscal 2022?

Agilent Technologies reported revenue of $6.85 billion in fiscal 2022.